Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Elizabeth K Asfaw"'
1
Integrins protect cardiomyocytes from ischemia/reperfusion injury
Autor: Yasuo Sugano, N. Chin Lai, Zheng Liu, Stephen J. Kaufman, Hideshi Okada, Derek J. Milner, Susan S. Taylor, Ana Maria Manso, Jorge Suarez, H. Kirk Hammond, Alexandre R. Gingras, Indroneal Banerjee, Sharon Israeli-Rosenberg, Elizabeth K. Asfaw, Wolfgang H. Dillmann, Jeffrey Copps, Seok Min Kang, Yoshitaka Kawaraguchi, Jan M. Schilling, Hemal H. Patel, Carol G. Au, Peter Liao, Guy Perkins, David M. Roth, Joshua I. Goldhaber, Robert S. Ross, Sunaho Okada-Maeda
Publikováno v: The Journal of clinical investigation, vol 123, iss 10
Ischemic damage is recognized to cause cardiomyocyte (CM) death and myocardial dysfunction, but the role of cell-matrix interactions and integrins in this process has not been extensively studied. Expression of α7β1D integrin, the dominant integrin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1fa54d4678fceb89e98e94cdae6845e
https://doi.org/10.1172/jci64216
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2
Abstract 320: Long-term Atorvastatin, But Not Pravastatin, Treatment Leads To Repressed Mitochondrial Gene Expression And Altered Cardiac Ultrastructure
Autor: Alice Zemljic-Harpf, Joseph C Godoy, Ingrid R Niesman, Jan M Schilling, Anna Schwarz, Elizabeth K Asfaw, Erika A Alvarez, Nancy D Dalton, Piyush M Patel, Brian P Head, John C Drummond, David M Roth, Georgios Kararigas, Hemal H Patel
Publikováno v: Circulation Research. 115
Statins reduce low-density lipoprotein cholesterol (LDL-C) and decrease cardiovascular events. Although statins are generally well tolerated, the FDA warns that statins may induce skeletal muscle side effects, cognitive changes and increased fasting
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fea85794f7f0d16e1eefe9d879ec7146
https://doi.org/10.1161/res.115.suppl_1.320
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3
Vinculin directly binds zonula occludens-1 and is essential for stabilizing connexin-43-containing gap junctions in cardiac myocytes
Autor: Joseph C. Godoy, Andrea A. Domenighetti, Elizabeth K. Asfaw, Anna R. Busija, Robert S. Ross, Oleksandr Platoshyn, Alice E. Zemljic-Harpf
Publikováno v: Journal of cell science. 127(Pt 5)
Vinculin (Vcl) links actin filaments to integrin and cadherin-based cellular junctions. Zonula occludens-1 (ZO-1) binds connexin-43 (Cx43), cadherin and actin. Vcl and ZO-1 anchor the actin cytoskeleton to the sarcolemma. Since loss of Vcl from cardi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec9ee4c5c09278cc01a42de318d8a62d
https://pubmed.ncbi.nlm.nih.gov/24413171
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7
Vinculin directly binds zonula occludens-1 and is essential for stabilizing connexin-43-containing gap junctions in cardiac myocytes
Autor: Alice E. Zemljic-Harpf, Anna R. Busija, Oleksandr Platoshyn, Robert S. Ross, Andrea A. Domenighetti, Elizabeth K. Asfaw, Joseph C. Godoy
Publikováno v: Development. 141:e708-e708
Vinculin (Vcl) links actin filaments to integrin- and cadherin-based cellular junctions. Zonula occludens-1 (ZO-1, also known as TJP1) binds connexin-43 (Cx43, also known as GJA1), cadherin and actin. Vcl and ZO-1 anchor the actin cytoskeleton to the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a1adb7c321a1260065bb7bcc2dacd430
https://doi.org/10.1242/dev.109553
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Plný text Recenzováno Digitální knihovna AV ČR
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