Výsledky vyhledávání - "Elizabeth Jewlal"

Connexin 43 contributes to phenotypic robustness of the mouse skull

Autor: Elizabeth Jewlal, Kevin J. Barr, Katherine E. Willmore, Dale W. Laird

Publikováno v: Developmental dynamics : an official publication of the American Association of AnatomistsREFERENCES. 250(12)

Background We compared skull shape and variation among genetically modified mice that exhibit different levels of connexin43 (Cx43) channel function, to determine whether Cx43 contributes to craniofacial phenotypic robustness. Specifically, we used t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c0f8491e77c8eaf567d71ac59123da
https://pubmed.ncbi.nlm.nih.gov/34091987

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Effects of Reduced Connexin43 Function on Mandibular Morphology and Osteogenesis in Mutant Mouse Models of Oculodentodigital Dysplasia

Autor: Katherine E. Willmore, Dale W. Laird, Kevin J. Barr, Alyssa C. Moore, Jessica J. Wu, Elizabeth Jewlal

Publikováno v: Bone and Joint Institute

© 2020, Springer Science+Business Media, LLC, part of Springer Nature. Mutations in the gene encoding the gap-junctional protein connexin43 (Cx43) are the cause of the human disease oculodentodigital dysplasia (ODDD). The mandible is often affected

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4211433f2e82c4e40c8e9c20a78ce28
https://pubmed.ncbi.nlm.nih.gov/32902679

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Double deletion of Panx1 and Panx3 affects skin and bone but not hearing

Autor: Silvia Penuela, Elizabeth Jewlal, Brooke L. O’Donnell, Julia M. Abitbol, John J. Kelly, C. B. Wakefield, Katherine E. Willmore, Brian L. Allman, Kevin J. Barr

Publikováno v: Anatomy and Cell Biology Publications

© 2019, Springer-Verlag GmbH Germany, part of Springer Nature. Abstract: Pannexins (Panxs), large-pore channel forming glycoproteins, are expressed in a wide variety of tissues including the skin, bone, and cochlea. To date, the use of single knock-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::866752f20f0dad876252bbc916793add
https://ir.lib.uwo.ca/anatomypub/131

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When Pap Testing Fails to Prevent Cervix Cancer: A Qualitative Study of the Experience of Screened Women Under 50 with Advanced Cervix Cancer in Canada

Autor: David D'Souza, Heather Shaddick, Elizabeth Jewlal, Mark T. Corkum, Akira Sugimoto, Nikhilesh Patil, Eric Leung, Michel Prefontaine, Jacob McGee

Publikováno v: Cureus

Introduction: While Papanicolaou (Pap) smears have resulted in a significant decline in cervical cancer incidence and mortality, our clinical experience indicates some women still present with locally advanced cervical cancer (LACC) despite having re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d9b814d6138596a4d28e1300101c54
http://europepmc.org/articles/PMC6433450

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Effects of reduced connexin43 function on skull development in the Cx43I130T/+ mutant mouse that models oculodentodigital dysplasia

Autor: Katherine E. Willmore, Dale W. Laird, Elizabeth Jewlal, Sommer G.E. Jarvis, Gregory M. Kelly, Kevin J. Barr, Jae Eun Lee

Publikováno v: Bone. 136:115365

Oculodentodigital dysplasia (ODDD) is a disease caused by mutations in the GJA1 gene that encodes the gap-junctional protein connexin43 (Cx43). ODDD affects multiple organs, but craniofacial anomalies are typical. However, details on the timing of ph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ad8193b917786d79be678a4f51a7da69
https://doi.org/10.1016/j.bone.2020.115365

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