Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Elizabeth J. Youngs"'
1
The Influence of Method of Administration and Covariates on the Pharmacokinetics of Propofol in Adult Volunteers
Autor: Elizabeth J. Youngs, Thomas W. Schnider, David B. Goodale, Corina Andresen, Charles F. Minto, Pedro L. Gambús, Steven L. Shafer
Publikováno v: Anesthesiology. 88:1170-1182
Background Unresolved issues with propofol include whether the pharmacokinetics are linear with dose, are influenced by method of administration (bolus vs. infusion), or are influenced by age. Recently, a new formulation of propofol emulsion, contain
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d35647dcc4f1448f9ac25026b9c1f3c
https://doi.org/10.1097/00000542-199805000-00006
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2
Influence of Age and Gender on the Pharmacokinetics and Pharmacodynamics of Remifentanil
Autor: Valerie Billard, Charles F. Minto, Thomas W. Schnider, Jaap W. Mandema, Talmage D. Egan, David J. Hermann, John F. Hoke, Steven L. Shafer, Pedro L. Gambús, Harry J. M. Lemmens, Katherine H. P. Moore, Keith T. Muir, Elizabeth J. Youngs
Publikováno v: Anesthesiology. 86:10-23
Background Previous studies have reported conflicting results concerning the influence of age and gender on the pharmacokinetics and pharmacodynamics of fentanyl, alfentanil, and sufentanil. The aim of this study was to determine the influence of age
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8b10b85f154bca0381b04a14764242b3
https://doi.org/10.1097/00000542-199701000-00004
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3
Multicenter Study of Target-Controlled Infusion of Propofol-Sufentanil or Sufentanil-Midazolam for Coronary Artery Bypass Graft Surgery
Autor: Simon C. Body, Richard L. Wolman, Joseph P. Mathew, Robert Wilson, Adam Zhang, Christina Mora Mangano, Uday Jain, Wayne H. Bellows, Dennis T. Mangano, Elizabeth J. Youngs
Publikováno v: Anesthesiology. 85:522-535
Background The use of target-controlled infusions of anesthetics for coronary artery bypass graft surgery has not been studied in detail. The effects of target-controlled infusions of propofol or sufentanil, supplemented by infusions of sufentanil or
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::96fdc0a7ac37be00a3f83ce81063b6ce
https://doi.org/10.1097/00000542-199609000-00011
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4
Pharmacokinetics of intravenous dynorphin A(1-13) in opioid-naive and opioid-treated human volunteers
Autor: Thomas W. Schnider, Valerie Billard, Steven L. Shafer, Günther Hochhaus, William G. Brose, Elizabeth J. Youngs, Pedro L. Gambús, Charles F. Minto
Publikováno v: Clinical pharmacology and therapeutics. 64(1)
Background Dynorphin A(1–13) is a fragment of the endogenous opioid neuropeptide dynorphin A. Previous research suggested that intravenously administered dynorphin A(1–13) has the ability to modulate morphine-induced analgesia. We designed this s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42431efcf40e770d58209c4b09e37c43
https://pubmed.ncbi.nlm.nih.gov/9695716
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5
Pharmacokinetic parameters relevant to recovery from opioids
Autor: Steven L. Shafer, Elizabeth J. Youngs
Publikováno v: Anesthesiology. 81(4)
Several recent studies have suggested that the terminal half-lives of many drugs do not predict the rate of washout of drug after the relatively short durations of infusions used in anesthesia. Many anesthetic drugs fit a three-compartment mamillary
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d6a34920a2103e41af81558d705066
https://pubmed.ncbi.nlm.nih.gov/7943834
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