Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Elizabeth J. Want"'
Autor:
Blerina Ahmetaj-Shala, Michael Olanipekun, Abel Tesfai, Niall MacCallum, Nicholas S. Kirkby, Gregory J. Quinlan, Chih-Chin Shih, Ryota Kawai, Sharon Mumby, Mark Paul-Clark, Elizabeth J. Want, Jane A. Mitchell
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Externí odkaz:
https://doaj.org/article/9334704285f14cf0b336bf208608e733
Autor:
Anke Nijhuis, Arti Sikka, Orli Yogev, Lili Herendi, Cristina Balcells, Yurui Ma, Evon Poon, Clare Eckold, Gabriel N. Valbuena, Yuewei Xu, Yusong Liu, Barbara Martins da Costa, Michael Gruet, Chiharu Wickremesinghe, Adrian Benito, Holger Kramer, Alex Montoya, David Carling, Elizabeth J. Want, Yann Jamin, Louis Chesler, Hector C. Keun
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The prognosis of high-risk neuroblastoma is poor despite the availability of multimodal treatment. Here the authors show that high-risk neuroblastoma is sensitive to indisulam, a selective degrader of the splicing factor RBM39 through the dual target
Externí odkaz:
https://doaj.org/article/c91ed6203d624310b8e94805ee7888bd
Autor:
Rachel Pilla, Tsz Hong Law, Yuanlong Pan, Brian M. Zanghi, Qinghong Li, Elizabeth J. Want, Jonathan A. Lidbury, Joerg M. Steiner, Jan S. Suchodolski, Holger Andreas Volk
Publikováno v:
Frontiers in Veterinary Science, Vol 7 (2020)
Consumption of diets containing medium chain triglycerides have been shown to confer neuroprotective and behavior modulating effects. We aimed to identify metabolic and microbiome perturbations in feces that are associated with consumption of a mediu
Externí odkaz:
https://doaj.org/article/695e4dfb427d40e586486a9c9b6153e6
Autor:
Chung-Ho E. Lau, Alexandros P. Siskos, Léa Maitre, Oliver Robinson, Toby J. Athersuch, Elizabeth J. Want, Jose Urquiza, Maribel Casas, Marina Vafeiadi, Theano Roumeliotaki, Rosemary R. C. McEachan, Rafaq Azad, Line S. Haug, Helle M. Meltzer, Sandra Andrusaityte, Inga Petraviciene, Regina Grazuleviciene, Cathrine Thomsen, John Wright, Remy Slama, Leda Chatzi, Martine Vrijheid, Hector C. Keun, Muireann Coen
Publikováno v:
BMC Medicine, Vol 16, Iss 1, Pp 1-19 (2018)
Abstract Background Environment and diet in early life can affect development and health throughout the life course. Metabolic phenotyping of urine and serum represents a complementary systems-wide approach to elucidate environment–health interacti
Externí odkaz:
https://doaj.org/article/a3108acadba449b3bdef3df4e9758ac4
Autor:
Sandrine P. Claus, Sandrine L. Ellero, Bernard Berger, Lutz Krause, Anne Bruttin, Jérôme Molina, Alain Paris, Elizabeth J. Want, Isabelle de Waziers, Olivier Cloarec, Selena E. Richards, Yulan Wang, Marc-Emmanuel Dumas, Alastair Ross, Serge Rezzi, Sunil Kochhar, Peter Van Bladeren, John C. Lindon, Elaine Holmes, Jeremy K. Nicholson
Publikováno v:
mBio, Vol 2, Iss 2 (2011)
ABSTRACT The gut microbiota enhances the host’s metabolic capacity for processing nutrients and drugs and modulate the activities of multiple pathways in a variety of organ systems. We have probed the systemic metabolic adaptation to gut colonizati
Externí odkaz:
https://doaj.org/article/db513350cc2244e59716cf1ce1fa7ee3
Publikováno v:
Current Treatment Options in Gastroenterology. 19:380-397
Purpose of review Cirrhosis is one of the most important global public health problems. Patients with cirrhosis risk progression to acute-on-chronic liver failure (ACLF), associated with high mortality rates, and development of hepatocellular carcino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55603555826311c644d3782e88b15fb6
https://doi.org/10.1007/s11938-021-00347-w
https://doi.org/10.1007/s11938-021-00347-w
Autor:
Virag Sagi-Kiss, Yufeng Li, Matthew R. Carey, Sarah J. Grover, Karsten Siems, Francesca Cirulli, Alessandra Berry, Chiara Musillo, Ian D. Wilson, Elizabeth J. Want, Jacob G. Bundy
Publikováno v:
Journal of proteome research. 21(6)
Liquid chromatography coupled to mass spectrometry is a key metabolomics/metabonomics technology. Reversed-phase liquid chromatography (RPLC) is very widely used as a separation step, but typically has poor retention of highly polar metabolites. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff9b1d8340ac5b6a69aacfcbf596ec4d
https://pubmed.ncbi.nlm.nih.gov/35536659
https://pubmed.ncbi.nlm.nih.gov/35536659
Autor:
Ian D. Wilson, Francesca Cirulli, Karsten Siems, Alessandra Berry, Jacob G. Bundy, Elizabeth J. Want, Yufeng Li, Sarah Grover, Virag Sagi-Kiss, Chiara Musillo, Matthew Carey
Liquid chromatography coupled to mass spectrometry is a key metabolomics technology. Reversed-phase liquid chromatog-raphy (RPLC) is very widely used as a separation step, possessing excellent characteristics with respect to reproducibility and relia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c524f35716f6308fc0a1c200b79dffd5
https://doi.org/10.33774/chemrxiv-2021-j9w16-v2
https://doi.org/10.33774/chemrxiv-2021-j9w16-v2
Autor:
Gonçalo Graça, Yuheng Cai, Chung-Ho E. Lau, Panagiotis A. Vorkas, Matthew R. Lewis, Elizabeth J. Want, David Herrington, Timothy M. D. Ebbels
Untargeted metabolomics and lipidomics LC-MS experiments produce complex datasets, usually containing tens of thousands of features from thousands of metabolites whose annotation requires additional MS/MS experiments and expert knowledge. All-ion fra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63fe6df04eab3c46a462cb45eca14312
http://hdl.handle.net/10044/1/93070
http://hdl.handle.net/10044/1/93070
Publikováno v:
Analytical Chemistry. 91:6541-6548
[Image: see text] Burn injury can be a devastating traumatic injury, with long-term personal and social implications for the patient. The many complex local and disseminating pathological processes underlying burn injury’s clinical challenges are o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a7d439cb30efaf52ab43b470eb5368
https://doi.org/10.1021/acs.analchem.8b05615
https://doi.org/10.1021/acs.analchem.8b05615