Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Elizabeth J. Tanner"'
Publikováno v:
PLoS Genetics, Vol 12, Iss 5, p e1005986 (2016)
Rapidly evolving viruses are a major threat to human health. Such viruses are often highly pathogenic (e.g., influenza virus, HIV, Ebola virus) and routinely circumvent therapeutic intervention through mutational escape. Error-prone genome replicatio
Externí odkaz:
https://doaj.org/article/b3e949fd1b084a80b1624bf4549432e9
Autor:
Elizabeth J Tanner, Hong-mei Liu, M Steven Oberste, Mark Pallansch, Marc S Collett, Karla Kirkegaard
Publikováno v:
eLife, Vol 3 (2014)
The emergence of drug resistance can defeat the successful treatment of pathogens that display high mutation rates, as exemplified by RNA viruses. Here we detail a new paradigm in which a single compound directed against a ‘dominant drug target’
Externí odkaz:
https://doaj.org/article/0571cfd5f2bc468a80a3125ae20d5046
Autor:
M. Steven Oberste, Karla Kirkegaard, Elizabeth J. Tanner, Mark A. Pallansch, Hong-Mei Liu, Marc S. Collett
Publikováno v:
eLife, Vol 3 (2014)
eLife
eLife
The emergence of drug resistance can defeat the successful treatment of pathogens that display high mutation rates, as exemplified by RNA viruses. Here we detail a new paradigm in which a single compound directed against a ‘dominant drug target’
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e3d3ab359708689ebcfefb1ad1bdbc6
https://elifesciences.org/articles/03830
https://elifesciences.org/articles/03830
Autor:
Jeannie F. Spagnolo, Esther Bullitt, Elizabeth J. Tanner, Karla Kirkegaard, Andres B. Tellez, Jing Wang
Catalytic activities can be facilitated by ordered enzymatic arrays that co-localize and orient enzymes and their substrates. The purified RNA-dependent RNA polymerase from poliovirus self-assembles to form two-dimensional lattices, possibly facilita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::300d35098acd5d0fccaf72ead6136f85
https://europepmc.org/articles/PMC3249232/
https://europepmc.org/articles/PMC3249232/
Autor:
Elizabeth J. Tanner, Larissa A. Singletary, Janet L. Gibson, Gregory J. McKenzie, Caleb Gonzalez, Susan M. Rosenberg, Peter L. Lee
Publikováno v:
Journal of bacteriology. 191(24)
The Escherichia coli chromosome encodes seven demonstrated type 2 toxin-antitoxin (TA) systems: cassettes of two or three cotranscribed genes, one encoding a stable toxin protein that can cause cell stasis or death, another encoding a labile antitoxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdcafbf5a812ca35f0883a651cf2a2e2
https://pubmed.ncbi.nlm.nih.gov/19837801
https://pubmed.ncbi.nlm.nih.gov/19837801