Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Elizabeth J. Ryan"'
Autor:
Vanessa Zaiatz-Bittencourt, Fiona Jones, Miriam Tosetto, Caitriona Scaife, Gerard Cagney, Evan Jones, Glen A. Doherty, Elizabeth J. Ryan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The gut microbiota regulates chronic inflammation and has been implicated in the pathogenesis of a broad spectrum of disease including autoimmunity and cancer. Microbial short-chain fatty acids (SCFAs) e.g., butyrate have demonstrated immuno
Externí odkaz:
https://doaj.org/article/7ea9284ffa394ea0a9f11c4623309226
Autor:
Alana Nash, Elizabeth J. Ryan
Publikováno v:
Tumour Virus Research, Vol 14, Iss , Pp 200246- (2022)
Herpesviruses evade host immunity to establish persistent lifelong infection with dormant latent and replicative lytic phases. Epstein-Barr virus (EBV) and Kaposi's Sarcoma-associated virus (KSHV) are double-stranded DNA herpesviruses that encode com
Externí odkaz:
https://doaj.org/article/096a9d59725a453a9dc6801361b37cf8
Autor:
Maria E. Morrissey, Róisín Byrne, Celina Nulty, Niamh H. McCabe, Niamh Lynam-Lennon, Clare T. Butler, Susan Kennedy, Dermot O’Toole, John Larkin, Paul McCormick, Brian Mehigan, Mary-Clare Cathcart, Joanne Lysaght, John V. Reynolds, Elizabeth J. Ryan, Margaret R. Dunne, Jacintha O’Sullivan
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Only 10–30% of oesophageal and rectal adenocarcinoma patients treated with neoadjuvant chemoradiotherapy have a complete pathological response. Inflammatory and angiogenic mediators in the tumour microenvironment (TME) may enabl
Externí odkaz:
https://doaj.org/article/eac61d4bd7544b4db891309c642d064c
Autor:
Alana Nash, Elizabeth J. Ryan
Publikováno v:
Animals, Vol 13, Iss 4, p 556 (2023)
The immune system of sea turtles is not completely understood. Sea turtles (as reptiles) bridge a unique evolutionary gap, being ectothermic vertebrates like fish and amphibians and amniotes like birds and mammals. Turtles are ectotherms; thus, their
Externí odkaz:
https://doaj.org/article/b2882936cfdf4dfe93ec9a6990f378f1
Autor:
Hannah K. Fitzgerald, Sinead A. O’Rourke, Eva Desmond, Nuno G. B. Neto, Michael G. Monaghan, Miriam Tosetto, Jayne Doherty, Elizabeth J. Ryan, Glen A. Doherty, Derek P. Nolan, Jean M. Fletcher, Aisling Dunne
Publikováno v:
Antioxidants, Vol 11, Iss 1, p 164 (2022)
The extracellular parasite and causative agent of African sleeping sickness Trypanosoma brucei (T. brucei) has evolved a number of strategies to avoid immune detection in the host. One recently described mechanism involves the conversion of host-deri
Externí odkaz:
https://doaj.org/article/daea71fc4daf47e5b167422d9b5c9366
Autor:
Jayne Doherty, Neil O Morain, Roisin Stack, Miriam Tosetto, Rosanna Inzitiari, Sophie O Reilly, Lili Gu, Juliette Sheridan, Garret Cullen, Edel Mc Dermott, Maire Buckley, Gareth Horgan, Hugh Mulcahy, Margaret Walshe, Elizabeth J Ryan, Virginie Gautier, John Prostko, Edwin Frias, David Daghfal, Peter Doran, Colm O Morain, Glen A Doherty
Publikováno v:
Journal of Crohn's and Colitis.
Background and Aims Patients with inflammatory bowel disease [IBD] have an attenuated response to initial COVID-19 vaccination. We sought to characterize the impact of IBD and its treatment on responses after the third vaccine against SARS-CoV-2. Met
Autor:
Fernanda Zamboni, Guang Ren, Mario Culebras, John O'Driscoll, Jack O'Dwyer, Elizabeth J. Ryan, Maurice N. Collins
Curcumin is a known naturally occurring anti-inflammatory agent derived from turmeric, and it is commonly used as a herbal food supplement. Here, in order to overcome the inherent hydrophobicity of curcumin (Cur), polylactic acid (PLA) nanoparticles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84ebcda16a639bebf98e3aed26afe0e
Autor:
Garret Cullen, Neil O' Morain, Roisin Stack, Cillian De Gascun, Jayne Doherty, Elizabeth J. Ryan, Glen A. Doherty, Sean Fennessy
Publikováno v:
Alimentary Pharmacology & Therapeutics
Summary Background Poor immune responses are frequently observed in patients with inflammatory bowel disease (IBD) receiving established vaccines; risk factors include immunosuppressants and active disease. Aims To summarise available information reg
Publikováno v:
Inflammatory Bowel Diseases
The cells of the immune system are highly dynamic, constantly sensing and adapting to changes in their surroundings. Complex metabolic pathways govern leukocytes’ ability to fine-tune their responses to external threats. Mammalian target of rapamyc
Publikováno v:
Journal of Crohn's & Colitis
Background and Aims Inflammatory bowel diseases [IBD], comprising Crohn’s disease [CD] and ulcerative colitis [UC], are chronic conditions characterized by severe dysregulation of innate and adaptive immunity resulting in the destruction of the int