Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Elizabeth J. Robertson"'
Autor:
Mubeen Goolam, Maria-Eleni Xypolita, Ita Costello, John P. Lydon, Francesco J. DeMayo, Elizabeth K. Bikoff, Elizabeth J. Robertson, Arne W. Mould
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The transcriptional repressor Blimp1/PRDM1 regulates cell fate decisions in the developing embryo and adult tissues. Here the authors show that conditional inactivation within maternal uterine tissues results in a defective primary decidual zone barr
Externí odkaz:
https://doaj.org/article/28a1cda4aae6436bbc84b29955a20204
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
How Nodal and Bmp pathways interact during primordial germ cell (PGC) formation remains unclear. Here, the authors show Nodal signalling via Eomes in the epiblast, together with Smad2 in the visceral endoderm, regulates formation of the mouse PGC lin
Externí odkaz:
https://doaj.org/article/d165dcef375f4774be02535361889157
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
The role of stem/progenitor cell populations in mammary gland morphogenesis is not well understood. Here, the authors show that a transcriptional repressor, Blimp1, is expressed in a rare luminal stem cell population, which contribute to duct formati
Externí odkaz:
https://doaj.org/article/4aff0135d8cd4c069ea5ad5641f3cb92
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Trophoblast stem cells (TSCs) give rise to specialized cell types within the placenta. However, the regulatory mechanisms that guide trophoblast cell fate decisions during placenta development remain ill defined. Here we exploited ATAC-seq a
Externí odkaz:
https://doaj.org/article/26d028b01be84c588d0195e0202b97a3
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The zinc finger transcriptional repressor Prdm1/Blimp1 is essential for remodelling maternal blood vessels in a subset of trophoblast cells. Here, the authors perform single-cell RNA-seq analysis on this Blimp1+ lineage, identifying functionally dist
Externí odkaz:
https://doaj.org/article/358498be65c14cc6abf10e9beb7b5ac5
Autor:
Karuna Sampath, Elizabeth J. Robertson
Publikováno v:
Open Biology, Vol 6, Iss 1 (2016)
Nodal is an evolutionarily conserved member of the transforming growth factor-β (TGF-β) superfamily of secreted signalling factors. Nodal factors are known to play key roles in embryonic development and asymmetry in a variety of organisms ranging f
Externí odkaz:
https://doaj.org/article/a05000a561da490b85f98aae87180a0c
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
Nature Communications 7: Article number: 11414 (2016), Published 25 April 2016; Updated 23 November 2018 In the original version of this Article, the accession codes section within the Methods was inadvertently omitted. This section has now been adde
Externí odkaz:
https://doaj.org/article/c1334db1bad046c2abe8afda2f71d8e1
Autor:
Richard R. Behringer, Robert G. McKinnell, Dimitri Viza, Alan O. Perantoni, Elizabeth J. Robertson, Sally L. Dunwoodie, Mark Lewandoski
Publikováno v:
Differentiation. 130:28-31
The International Society of Differentiation was born from the First International Conference on Cell Differentiation conceived by D.V. and held in Nice, France in 1971. The conference also resulted in the creation of the journal of the Society named
Autor:
Claire S. Simon, Lucas Greder, Elizabeth J. Robertson, Anna D. Senft, Ivan Imaz-Rosshandler, Catherine Porcher, Luke T. G. Harland, Marella F. T. R. de Bruijn, John C. Marioni, Berthold Göttgens, Elizabeth K. Bikoff, Ita Costello
Publikováno v:
Nature cell biology
Extra-embryonic mesoderm (ExM)-composed of the earliest cells that traverse the primitive streak-gives rise to the endothelium as well as haematopoietic progenitors in the developing yolk sac. How a specific subset of ExM becomes committed to a haema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebea60a8636375dc06989f547165bfe6
Autor:
Elizabeth K. Bikoff, Francesco J. DeMayo, Mubeen Goolam, John P. Lydon, Elizabeth J. Robertson, Ita Costello, Arne W. Mould, Maria-Eleni Xypolita
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The transcriptional repressor Blimp1 controls cell fate decisions in the developing embryo and adult tissues. Here we describe Blimp1 expression and functional requirements within maternal uterine tissues during pregnancy. Expression is robustly up-r