Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Elizabeth J. Penn"'
Autor:
Francisco J. Salguero, Andrew D. White, Gillian S. Slack, Susan A. Fotheringham, Kevin R. Bewley, Karen E. Gooch, Stephanie Longet, Holly E. Humphries, Robert J. Watson, Laura Hunter, Kathryn A. Ryan, Yper Hall, Laura Sibley, Charlotte Sarfas, Lauren Allen, Marilyn Aram, Emily Brunt, Phillip Brown, Karen R. Buttigieg, Breeze E. Cavell, Rebecca Cobb, Naomi S. Coombes, Alistair Darby, Owen Daykin-Pont, Michael J. Elmore, Isabel Garcia-Dorival, Konstantinos Gkolfinos, Kerry J. Godwin, Jade Gouriet, Rachel Halkerston, Debbie J. Harris, Thomas Hender, Catherine M. K. Ho, Chelsea L. Kennard, Daniel Knott, Stephanie Leung, Vanessa Lucas, Adam Mabbutt, Alexandra L. Morrison, Charlotte Nelson, Didier Ngabo, Jemma Paterson, Elizabeth J. Penn, Steve Pullan, Irene Taylor, Tom Tipton, Stephen Thomas, Julia A. Tree, Carrie Turner, Edith Vamos, Nadina Wand, Nathan R. Wiblin, Sue Charlton, Xiaofeng Dong, Bassam Hallis, Geoffrey Pearson, Emma L. Rayner, Andrew G. Nicholson, Simon G. Funnell, Julian A. Hiscox, Mike J. Dennis, Fergus V. Gleeson, Sally Sharpe, Miles W. Carroll
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Non-human primates are important animal models for studying SARS-CoV-2 infection. Here, Salguero et al. directly compare rhesus and cynomolgus macaques and show that both species represent COVID-19 disease of mild clinical cases, and provide a lung h
Externí odkaz:
https://doaj.org/article/87631802f4e34ba091e1f0a793783536
Autor:
Kathryn A. Ryan, Kevin R. Bewley, Susan A. Fotheringham, Gillian S. Slack, Phillip Brown, Yper Hall, Nadina I. Wand, Anthony C. Marriott, Breeze E. Cavell, Julia A. Tree, Lauren Allen, Marilyn J. Aram, Thomas J. Bean, Emily Brunt, Karen R. Buttigieg, Daniel P. Carter, Rebecca Cobb, Naomi S. Coombes, Steve J. Findlay-Wilson, Kerry J. Godwin, Karen E. Gooch, Jade Gouriet, Rachel Halkerston, Debbie J. Harris, Thomas H. Hender, Holly E. Humphries, Laura Hunter, Catherine M. K. Ho, Chelsea L. Kennard, Stephanie Leung, Stephanie Longet, Didier Ngabo, Karen L. Osman, Jemma Paterson, Elizabeth J. Penn, Steven T. Pullan, Emma Rayner, Oliver Skinner, Kimberley Steeds, Irene Taylor, Tom Tipton, Stephen Thomas, Carrie Turner, Robert J. Watson, Nathan R. Wiblin, Sue Charlton, Bassam Hallis, Julian A. Hiscox, Simon Funnell, Mike J. Dennis, Catherine J. Whittaker, Michael G. Catton, Julian Druce, Francisco J. Salguero, Miles W. Carroll
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
SARS-CoV-2 induces mild infection in ferret model. Here, Ryan et al. characterise optimal infection dosage inducing upper respiratory tract (UTR) viral shedding, progression time of viral shedding, and pathology in ferrets and finally provide evidenc
Externí odkaz:
https://doaj.org/article/a8afc90cbc2f4422be7dc5bc8923c3cf
Autor:
Kathryn A Ryan, Kevin R Bewley, Robert J Watson, Christopher Burton, Oliver Carnell, Breeze E Cavell, Amy Challis, Naomi S Coombes, Elizabeth R Davies, Jack Edun-Huges, Kirsty Emery, Rachel Fell, Susan A Fotheringham, Karen E Gooch, Kathryn Gowan, Alastair Handley, Debbie J Harris, Richard Hesp, Laura Hunter, Richard Humphreys, Rachel Johnson, Chelsea Kennard, Daniel Knott, Sian Lister, Daniel Morley, Didier Ngabo, Karen L Osman, Jemma Paterson, Elizabeth J Penn, Steven T Pullan, Kevin S Richards, Sian Summers, Stephen R Thomas, Thomas Weldon, Nathan R Wiblin, Emma L Rayner, Richard T Vipond, Bassam Hallis, Francisco J Salguero, Simon G P Funnell, Yper Hall
Publikováno v:
PLoS Pathogens, Vol 19, Iss 4, p e1011293 (2023)
The mutation profile of the SARS-CoV-2 Omicron (lineage BA.1) variant posed a concern for naturally acquired and vaccine-induced immunity. We investigated the ability of prior infection with an early SARS-CoV-2 ancestral isolate (Australia/VIC01/2020
Externí odkaz:
https://doaj.org/article/53f97256995a48939823b3b8dfbb9267
Autor:
Helen Parry, Gokhan Tut, Rachel Bruton, Sian Faustini, Christine Stephens, Philip Saunders, Christopher Bentley, Katherine Hilyard, Kevin Brown, Gayatri Amirthalingam, Sue Charlton, Stephanie Leung, Emily Chiplin, Naomi S Coombes, Kevin R Bewley, Elizabeth J Penn, Cathy Rowe, Ashley Otter, Rosie Watts, Silvia D'Arcangelo, Bassam Hallis, Andrew Makin, Alex Richter, Jianmin Zuo, Paul Moss
Publikováno v:
eLife, Vol 10 (2021)
Age is the major risk factor for mortality after SARS-CoV-2 infection and older people have received priority consideration for COVID-19 vaccination. However, vaccine responses are often suboptimal in this age group and few people over the age of 80
Externí odkaz:
https://doaj.org/article/f03f1cad0695471492d26dc7d9bac0ad
Autor:
Naomi Coombes, Lorna McInroy, Lauren Allen, Greg Kulnis, Luc Gagnon, Emily Brunt, Natalie St-Amant, Karen R. Buttigieg, Kevin R. Bewley, Kelly M. Thomas, Simon G. P. Funnell, Holly E. Humphries, Miles W. Carroll, Sue Charlton, Phillip Brown, Kerry J Godwin, Elizabeth J Penn, Bassam Hallis, Julien R St-Jean, Stephanie Leung, Natalie Baker, Imam Shaik
Publikováno v:
Nature Protocols. 16:3114-3140
Virus neutralization assays measure neutralizing antibodies in serum and plasma, and the plaque reduction neutralization test (PRNT) is considered the gold standard for measuring levels of these antibodies for many viral diseases. We have developed p
Autor:
Nadina Wand, Irene Taylor, Didier Ngabo, Vanessa Lucas, Rebecca Cobb, Rachel Halkerston, Susan A. Fotheringham, Stephanie Leung, Alexandra L. Morrison, Tom Tipton, Holly E. Humphries, Bassam Hallis, Phillip Brown, Kerry J Godwin, Stephen Thomas, Isabel García-Dorival, Emily Brunt, Robert J. Watson, Thomas Hender, Charlotte Nelson, Laura Hunter, Andrew White, Gillian S. Slack, Michael J. Elmore, Owen Daykin-Pont, Nathan R Wiblin, Miles W. Carroll, Breeze E. Cavell, Charlotte Sarfas, Simon G. P. Funnell, Francisco J. Salguero, Karen R. Buttigieg, Carrie Turner, Kevin R. Bewley, Jade Gouriet, Yper Hall, Marilyn Aram, Kathryn A. Ryan, Adam Mabbutt, Steve Pullan, Konstantinos Gkolfinos, Julia A. Tree, Geoffrey Pearson, Lauren Allen, Debbie J Harris, Andrew G. Nicholson, Sue Charlton, Alistair C. Darby, Naomi Coombes, Edith Vamos, Daniel Knott, Karen E. Gooch, Catherine M K Ho, Stephanie Longet, Chelsea L Kennard, Julian A. Hiscox, Xiaofeng Dong, Jemma Paterson, Mike Dennis, Emma Rayner, Fergus V. Gleeson, Elizabeth J Penn, Sally Sharpe, Laura Sibley
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
NATURE COMMUNICATIONS
Nature Communications
NATURE COMMUNICATIONS
Nature Communications
A novel coronavirus, SARS-CoV-2, has been identified as the causative agent of the current COVID-19 pandemic. Animal models, and in particular non-human primates, are essential to understand the pathogenesis of emerging diseases and to assess the saf
Autor:
Kathryn A. Ryan, Robert J. Watson, Kevin R. Bewley, Christopher Burton, Oliver Carnell, Breeze E. Cavell, Amy Challis, Naomi S. Coombes, Kirsty Emery, Rachel Fell, Susan A. Fotheringham, Karen E. Gooch, Kathryn Gowan, Alastair Handley, Debbie J. Harris, Richard Humphreys, Rachel Johnson, Daniel Knott, Sian Lister, Daniel Morley, Didier Ngabo, Karen L. Osman, Jemma Paterson, Elizabeth J. Penn, Steven T. Pullan, Kevin S. Richards, Imam Shaik, Sian Summers, Stephen R. Thomas, Thomas Weldon, Nathan R. Wiblin, Richard Vipond, Bassam Hallis, Simon G. P. Funnell, Yper Hall
The mutation profile of the SARS-CoV-2 Omicron variant poses a concern for naturally acquired and vaccine-induced immunity. We investigated the ability of prior infection with an early SARS-CoV-2, 99.99% identical to Wuhan-Hu-1, to protect against di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc142a0855eea8d783ac8d7353547ed8
https://doi.org/10.1101/2021.12.24.474081
https://doi.org/10.1101/2021.12.24.474081
Autor:
Holly E. Humphries, Lauren Allen, Frances Alexander, Andrew Gorringe, Rachel Halkerston, Elodie Lesne, Stephen Taylor, Emily Brunt, Stephen Thomas, Elizabeth J Penn, Breeze E. Cavell, Stephanie Leung
Publikováno v:
Methods in Molecular Biology ISBN: 9781071618998
Complement is a key component of functional immunological assays used to evaluate vaccine-mediated immunity to a range of bacterial and viral pathogens. However, standardization of these assays is complicated due to the availability of a human comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93838579e3eb77b55c1ea5e0b3aafabc
https://doi.org/10.1007/978-1-0716-1900-1_18
https://doi.org/10.1007/978-1-0716-1900-1_18
Autor:
Cathy Rowe, Christine Stephens, Emily Chiplin, Christopher Bentley, Katherine Hilyard, Sue Charlton, Naomi Coombes, Gokhan Tut, Bassam Hallis, Gayatri Amirthalingam, Alex G. Richter, Ashley Otter, Rachel Bruton, Elizabeth J Penn, Andrew Makin, Jianmin Zuo, Philip Saunders, Kevin R. Bewley, Stephanie Leung, Helen Parry, Rosie Watts, Sian E Faustini, Paul Moss, Silvia D'Arcangelo, Kevin E. Brown
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Age is the major risk factor for mortality after SARS-CoV-2 infection and older people have received priority consideration for COVID-19 vaccination. However, vaccine responses are often suboptimal in this age group and few people over the age of 80
Autor:
Helen Parry, Gokhan Tut, Rachel Bruton, Sian Faustini, Christine Stephens, Philip Saunders, Christopher Bentley, Katherine Hilyard, Kevin Brown, Gayatri Amirthalingam, Sue Charlton, Stephanie Leung, Emily Chiplin, Naomi S Coombes, Kevin R Bewley, Elizabeth J Penn, Cathy Rowe, Ashley Otter, Rosie Watts, Silvia D'Arcangelo, Bassam Hallis, Andrew Makin, Alex Richter, Jianmin Zuo, Paul Moss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef5a30e591856bc35532205e025dd37e
https://doi.org/10.7554/elife.69375.sa2
https://doi.org/10.7554/elife.69375.sa2