Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Elizabeth J. Orwin"'
Autor:
Nancy K. Lape, Angie Lee, Albert Dato, Roberta M. Ewart, Christopher M. Clark, TJ Tsai, Lori Bassman, Elizabeth J. Orwin, Matthew Spencer, Erik Spjut, Joseph Betser, Laura Palucki-Blake
Publikováno v:
AIAA SPACE and Astronautics Forum and Exposition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6236bb4fa157118f851e1c6d21721b1
https://doi.org/10.2514/6.2017-5175
https://doi.org/10.2514/6.2017-5175
Publikováno v:
Tissue Engineering Part A. 19:1564-1572
Corneal disease is the fourth leading cause of blindness. According to the World Health Organization, roughly 1.6 million people globally are blind as a result of this disease. The only current treatment for corneal opacity is a corneal tissue transp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ddb7cc09ff8aa75a92ad8899f49dd2c
https://doi.org/10.1089/ten.tea.2012.0084
https://doi.org/10.1089/ten.tea.2012.0084
Publikováno v:
Biotechnology and Bioengineering. 109:3189-3198
Mechanical strain is an important signal that influences the behavior and properties of cells in a wide variety of tissues. Physiologically similar mechanical strain can revert cultured cells to a more normal phenotype. Here, we have demonstrated tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cac6f3878fbf998c3ad45022980aa26
https://doi.org/10.1002/bit.24587
https://doi.org/10.1002/bit.24587
Publikováno v:
Tissue Engineering Part A. 17:799-807
Corneal blindness is a significant problem treated primarily by corneal transplants. Donor tissue supply is low, creating a growing need for an alternative. A tissue-engineered cornea made from patient-derived cells and biopolymer scaffold materials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cbd72b9435846d55797c06dec394df2
https://doi.org/10.1089/ten.tea.2009.0724
https://doi.org/10.1089/ten.tea.2009.0724
Publikováno v:
Pediatric Research. 63:535-544
The field of corneal tissue engineering has made many strides in recent years. The challenges of engineering a biocompatible, mechanically stable, and optically transparent tissue are significant. To overcome these challenges, researchers have adopte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e53bff3241461837338967910cdc4d3c
https://doi.org/10.1203/pdr.0b013e31816bdf54
https://doi.org/10.1203/pdr.0b013e31816bdf54
Publikováno v:
Journal of Biomechanical Engineering. 125:439-444
Cell matrix interactions are important in understanding the healing characteristics of the cornea after refractive surgery or transplantation. The purpose of this study was to characterize in more detail the evolution of biomechanical and optical pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdd2769ed7ceddb8759ce6bb4fa1ed09
https://doi.org/10.1115/1.1589773
https://doi.org/10.1115/1.1589773
Autor:
Alanna L. Weisberg, Elizabeth J. Orwin, Theodore B. DuBose, Nathaniel J. H. Bean, Richard C. Haskell
Publikováno v:
SPIE Proceedings.
Excessive nonspecific binding often occurs when labeling cells with immuno-labeled gold nanoparticles (IgG-AuNPs). We have investigated the physical properties of IgG-AuNPs assembled with three different protocols in an attempt to understand and elim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff411a04aabd613148e01abe292609dc
https://doi.org/10.1117/12.2041714
https://doi.org/10.1117/12.2041714
Autor:
Donna Phu, Elizabeth J. Orwin
Publikováno v:
2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.
The cornea is responsible for functional optical activity of the mammalian eye, as it must remain transparent in order to focus light onto the retina. Corneal disease is the second leading cause worldwide of vision loss [1]. Human donor tissue transp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23544dbc33a918e27a979aae0da94a22
https://doi.org/10.1109/iembs.2009.5332702
https://doi.org/10.1109/iembs.2009.5332702
Autor:
Lindsay Wray, Elizabeth J. Orwin
Publikováno v:
Tissue engineering. Part A. 15(7)
A viable tissue-engineered corneal replacement needs to be transparent and mechanically resilient. One necessary element for achieving this level of functionality is a scaffolding material that minimizes backscattered light, supports cellular growth,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b95f332720be12f2f7ac8c8e5c991a
https://pubmed.ncbi.nlm.nih.gov/19193140
https://pubmed.ncbi.nlm.nih.gov/19193140
We have met all of the milestones outlined in this grant, except demonstration that the electrospun conduit supports cell growth. Composite gels are a more promising method for the brain patch therapy due to greater degree of control over shape of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edbec9f41f0dfabe6c519485b054904a
https://doi.org/10.21236/ada482999
https://doi.org/10.21236/ada482999
