Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Elizabeth J. Klemm"'
Autor:
Sandra Van Puyvelde, Derek Pickard, Koen Vandelannoote, Eva Heinz, Barbara Barbé, Tessa de Block, Simon Clare, Eve L. Coomber, Katherine Harcourt, Sushmita Sridhar, Emily A. Lees, Nicole E. Wheeler, Elizabeth J. Klemm, Laura Kuijpers, Lisette Mbuyi Kalonji, Marie-France Phoba, Dadi Falay, Dauly Ngbonda, Octavie Lunguya, Jan Jacobs, Gordon Dougan, Stijn Deborggraeve
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Invasive non-typhoidal Salmonella (iNTS) infections are dominated by antibiotic resistant isolates of the sequence type (ST) 313. Here, the authors identify the ST313 sublineage II.1 in the Democratic Republic of the Congo exhibiting extensive drug r
Externí odkaz:
https://doaj.org/article/d03041f0c2d4477dbba22683cea763a0
Autor:
Edna M. Ondari, Elizabeth J. Klemm, Chisomo L. Msefula, Moataz Abd El Ghany, Jennifer N. Heath, Derek J. Pickard, Lars Barquist, Gordon Dougan, Robert A. Kingsley, Calman A. MacLennan
Publikováno v:
Wellcome Open Research, Vol 4 (2019)
Background: Salmonella Typhimurium ST313 exhibits signatures of adaptation to invasive human infection, including higher resistance to humoral immune responses than gastrointestinal isolates. Full resistance to antibody-mediated complement killing (s
Externí odkaz:
https://doaj.org/article/e76cf5de64bc47299dbe1bae4d6deefa
Autor:
Elizabeth J. Klemm, Sadia Shakoor, Andrew J. Page, Farah Naz Qamar, Kim Judge, Dania K. Saeed, Vanessa K. Wong, Timothy J. Dallman, Satheesh Nair, Stephen Baker, Ghazala Shaheen, Shahida Qureshi, Mohammad Tahir Yousafzai, Muhammad Khalid Saleem, Zahra Hasan, Gordon Dougan, Rumina Hasan
Publikováno v:
mBio, Vol 9, Iss 1 (2018)
ABSTRACT Antibiotic resistance is a major problem in Salmonella enterica serovar Typhi, the causative agent of typhoid. Multidrug-resistant (MDR) isolates are prevalent in parts of Asia and Africa and are often associated with the dominant H58 haplot
Externí odkaz:
https://doaj.org/article/83d1da76553346da82eb5ef1f2ae6c0b
Autor:
Sadia Isfat Ara Rahman, Zoe A Dyson, Elizabeth J Klemm, Farhana Khanam, Kathryn E Holt, Emran Kabir Chowdhury, Gordon Dougan, Firdausi Qadri
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 2, p e0008036 (2020)
BackgroundMulti-drug resistant typhoid fever remains an enormous public health threat in low and middle-income countries. However, we still lack a detailed understanding of the epidemiology and genomics of S. Typhi in many regions. Here we have under
Externí odkaz:
https://doaj.org/article/891ddf95062c4fb98ddf29a869284e0e
Autor:
Mark R, Davies, Sebastian, Duchene, Mary, Valcanis, Aaron P, Jenkins, Adam, Jenney, Varanisese, Rosa, Andrew J, Hayes, Aneley Getahun, Strobel, Liam, McIntyre, Jake A, Lacey, Elizabeth J, Klemm, Vanessa K, Wong, Aalisha, Sahukhan, Helen, Thomson, Andrew, Page, Dianna, Hocking, Nancy, Wang, Litia, Tudravu, Eric, Rafai, Gordon, Dougan, Benjamin P, Howden, John A, Crump, Kim, Mulholland, Richard A, Strugnell
Publikováno v:
The Lancet regional health. Western Pacific. 24
Typhoid fever is endemic in some Pacific Island Countries including Fiji and Samoa yet genomic surveillance is not routine in such settings. Previous studies suggested imports of the global H58 clade ofGenomic sequencing approaches were implemented t
Autor:
Jennifer Cable, Rino Rappuoli, Elizabeth J. Klemm, Gagandeep Kang, Ankur Mutreja, Gavin J. Wright, Mariagrazia Pizza, Sowmya Ajay Castro, Joseph P. Hoffmann, Galit Alter, Andrea Carfi, Andrew J. Pollard, Florian Krammer, Ravindra K. Gupta, Caroline E. Wagner, Viviane Machado, Kayvon Modjarrad, Lawrence Corey, Peter B. Gilbert, Gordon Dougan, Nicole Lurie, Pamela J. Bjorkman, Christopher Chiu, Elisa Nemes, Stephen B. Gordon, Andrew C. Steer, Thomas Rudel, Catherine A. Blish, John Tyler Sandberg, Kiva Brennan, Keith P. Klugman, Lynda M. Stuart, Shabir A. Madhi, Christopher L. Karp
Publikováno v:
Annals of the New York Academy of Sciences
The rapid development of COVID-19 vaccines was the result of decades of research to establish flexible vaccine platforms and understand pathogens with pandemic potential, as well as several novel changes to the vaccine discovery and development proce
Publikováno v:
PloS one. 17(5)
Background The “Ending Cholera: A Global Roadmap to 2030” (Roadmap) was launched in October 2017. Following its launch, it became clear that additional evidence is needed to assist countries in controlling cholera and that a prioritized list of r
Autor:
Elizabeth J. Klemm, Nicholas Henschke, Mical Paul, Hanna Bergman, Becky Skidmore, Gemma Villanueva, Chantelle Garritty, Brian S Buckley
Publikováno v:
Clinical Microbiology and Infection. 25:1213-1225
Background Vaccines may reduce antibiotic use and the development of resistance. Objectives To provide a comprehensive, up-to-date assessment of the evidence base relating to the effect of vaccines on antibiotic use. Data sources Ovid MEDLINE, Embase
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Multiple drug (antibiotic) resistance (MDR) has become a major threat to the treatment of typhoid and other infectious diseases. Since the 1970s, this threat has increased in Salmonella enterica serovar Typhi, driven in part by the emergence of succe
Autor:
Mark R. Davies, Sebastian Duchene, Mary Valcanis, Aaron P. Jenkins, Adam Jenney, Varanisese Rosa, Andrew J. Hayes, Aneley Getahun Strobel, Liam McIntyre, Jake A. Lacey, Elizabeth J. Klemm, Vanessa K. Wong, Aalisha Sahukhan, Helen Thomson, Andrew Page, Dianna Hocking, Nancy Wang, Litia Tudravu, Eric Rafai, Gordon Dougan, Benjamin P. Howden, John A. Crump, Kim Mulholland, Richard A. Strugnell
Publikováno v:
The Lancet Regional Health - Western Pacific. 24:100488