Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Elizabeth J. Kemp"'
Autor:
Roy Ward, David J. Kavanagh, Robin J. Winney, Anna Richards, Elizabeth Mayland, Jeremy S. Duffield, Timothy H.J. Goodship, Graham Warwick, Elizabeth J. Kemp, Judith A. Goodship
Publikováno v:
Journal of the American Society of Nephrology. 16:2150-2155
Mutations in the plasma complement regulator factor H (CFH) and the transmembrane complement regulator membrane co-factor protein (MCP) have been shown to predispose to atypical hemolytic uremic syndrome (HUS). Both of these proteins act as co-factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa655dd94d10f0502c56cca93c5681dd
https://doi.org/10.1681/asn.2005010103
https://doi.org/10.1681/asn.2005010103
Autor:
Lisa Strain, Timothy H.J. Goodship, Chantal Loirat, Elizabeth J. Kemp, Hong-Wen Deng, Marie-Agnès Dragon-Durey, Véronique Frémeaux-Bacchi, Judith A. Goodship
Publikováno v:
Journal of Medical Genetics. 42:852-856
Background: In both familial and sporadic atypical haemolytic-uraemic syndrome (aHUS), mutations have been reported in regulators of the alternative complement pathway including factor H (CFH), membrane cofactor protein (MCP), and the serine protease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a99432cc8d92deaf8b71f90c9742118
https://doi.org/10.1136/jmg.2005.030783
https://doi.org/10.1136/jmg.2005.030783
Autor:
Martha Diaz-Torres, Judith A. Goodship, Elizabeth J. Kemp, Lisa Strain, Timothy H.J. Goodship
Publikováno v:
Journal of Thrombosis and Haemostasis. 3:2128-2130
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55c591f1c0444550620ec55add0da585
https://doi.org/10.1111/j.1538-7836.2005.01548.x
https://doi.org/10.1111/j.1538-7836.2005.01548.x
Autor:
Stefan Heinen, Judith A. Goodship, Santiago Rodríguez de Córdoba, Christine Skerka, Michael S. Jackson, T. Sakari Jokiranta, Pierre Robitaille, Lisa Strain, Timothy H.J. Goodship, Elizabeth J. Kemp, Pilar Sánchez-Corral, Kevin E.C. Meyers, Jorge Esparza-Gordillo, Eric Wagner, Peter F. Zipfel
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scopus-Elsevier
instname
Scopus-Elsevier
3 páginas, 4 figuras, 2 apéndices -- PAGS nros. 292-293
Many of the complement regulatory genes within the RCA cluster (1q32) have arisen through genomic duplication and the resulting high degree of sequence identity is likely to predispose to
Many of the complement regulatory genes within the RCA cluster (1q32) have arisen through genomic duplication and the resulting high degree of sequence identity is likely to predispose to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8988db3a81b9a1b2a3fd4830ee29b84
https://pubmed.ncbi.nlm.nih.gov/16470555
https://pubmed.ncbi.nlm.nih.gov/16470555
Autor:
David J. Kavanagh, Anna Richards, Elizabeth Mayland, Rachel M. Burgess, Timothy H.J. Goodship, Judith Goodship, Elizabeth J. Kemp
Publikováno v:
Molecular immunology. 43(7)
Atypical haemolytic uraemic syndrome (aHUS) is a disorder of complement dysregulation. Because complement factor B (fB) carries the catalytic site of the alternative pathway convertase we examined it as both a potential candidate gene and modifier in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb15920a4a26bbb6288bb2863a3c244
https://pubmed.ncbi.nlm.nih.gov/16061287
https://pubmed.ncbi.nlm.nih.gov/16061287
Autor:
Anna Richards, M. Kathryn Liszewski, John P. Atkinson, Elizabeth J. Kemp, Timothy H.J. Goodship
Publikováno v:
Trends in molecular medicine. 10(5)
Membrane cofactor protein (MCP, CD46) is a widely expressed transmembrane complement regulator. As does the soluble regulator factor H, it inhibits complement activation by inactivating the C3b that is deposited on target membranes. Factor H mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02015dbeb90437c5ff6210b0ce158303
https://pubmed.ncbi.nlm.nih.gov/15121049
https://pubmed.ncbi.nlm.nih.gov/15121049
Autor:
Salih Kavukcu, Judith A. Goodship, M Hamza Müslümanoğlu, John P. Atkinson, Ronny Decorte, Yves Pirson, M. Kathryn Liszewski, Guido Filler, Elizabeth J. Kemp, Anna Richards, Timothy H.J. Goodship, AK Lampe, Leana S. Wen
Membrane cofactor protein (MCP; CD46) is a widely expressed transmembrane complement regulator. Like factor H it inhibits complement activation by regulating C3b deposition on targets. Factor H mutations occur in 10-20% of patients with hemolytic ure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e3ec2eb1121fb6dacc1885ea694529e
https://avesis.deu.edu.tr/publication/details/09a7b351-4afa-464d-937e-0e7ce55cfb5d/oai
https://avesis.deu.edu.tr/publication/details/09a7b351-4afa-464d-937e-0e7ce55cfb5d/oai
