Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Elizabeth J. Fisher"'
Autor:
Elizabeth J. Fisher, Susan V. McLennan, Alison K. Death, Dennis K. Yue, Sally Y. Martell, Paul F. Williams, J. Guy Lyons
Publikováno v:
Kidney International. 58:S81-S87
Effects of glucose on matrix metalloproteinase and plasmin activities in mesangial cells: Possible role in diabetic nephropathy. Diabetic nephropathy is characterized by an accumulation of mesangium matrix that correlates well with the loss of kidney
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5ad3dbea1185733d2b370ae989456c6
https://doi.org/10.1046/j.1523-1755.2000.07713.x
https://doi.org/10.1046/j.1523-1755.2000.07713.x
Publikováno v:
Nephron. 80:277-284
The important role of ascorbic acid (AA) as an anti-oxidant is particularly relevant in diabetes mellitus where plasma concentrations of AA are reduced. This study was conducted to evaluate the effects of treatment with AA or an aldose reductase inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8635871130c3078698b8d6d85e738bef
https://doi.org/10.1159/000045187
https://doi.org/10.1159/000045187
Publikováno v:
Diabetes Research and Clinical Practice. 37:101-108
Expansion of the glomerular mesangium is a consistent finding of diabetic nephropathy. Negatively charged proteoglycans are an integral part of the mesangium and their synthesis and degradation is disturbed in many forms of glomerulosclerosis. The me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8ab0ed54e9df2a6a1c9489494419abc
https://doi.org/10.1016/s0168-8227(97)00063-6
https://doi.org/10.1016/s0168-8227(97)00063-6
Publikováno v:
Microvascular Research. 53:173-178
Mesangium enlargement is a central feature of diabetic nephropathy and almost certainly plays a pathogenic role in this condition. Previous studies have shown that mesangium degradation is reduced in a high glucose mileau. Plasmin has been shown to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29beb2b36a90060da25b642d2c3b6b78
https://doi.org/10.1006/mvre.1996.2006
https://doi.org/10.1006/mvre.1996.2006
Publikováno v:
Diabetic Medicine. 13:758-763
Nephropathy is a serious microvascular complication of diabetes mellitus which is preceded by a period of microalbuminura. Increased loss of proteoglycan (PG) from glomerular basement (GBM) has been postulated to alter glomerular charge selectivity w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4612a521f897af7d253210fbae6d6067
https://doi.org/10.1002/(sici)1096-9136(199608)13:8<758::aid-dia160>3.0.co
https://doi.org/10.1002/(sici)1096-9136(199608)13:8<758::aid-dia160>3.0.co
Publikováno v:
Microvascular Research. 48:179-189
Abnormalities of retinal pericytes and endothelial cells are prominent features of diabetic retinopathy. In this study, we used cultures of bovine retinal cells to examine the regulation of cell-associated proteoglycans, a class of highly sulfated ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffea7ecfa2fdcc5af4092506cb5b0b4f
https://doi.org/10.1006/mvre.1994.1048
https://doi.org/10.1006/mvre.1994.1048
Autor:
Susan V. McLennan, Hisaya Tada, Dennis K. Yue, Elizabeth J. Fisher, Scott Heffernan, John R. Turtle
Publikováno v:
Diabetes. 40:371-376
Collagen and proteoglycans are two major constituents of the extracellular matrix, and their abnormalities have been incriminated in the pathogenesis of diabetic complications. A decrease of plasma ascorbic acid has been reported in diabetes and thus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::791613d3eb1a9b608c549e6af3c06ec6
https://doi.org/10.2337/diab.40.3.371
https://doi.org/10.2337/diab.40.3.371
Autor:
Margaret McGill, Scott Heffernan, Elizabeth J. Fisher, C. Capogreco, John R. Turtle, S. McLennan, Dennis K. Yue
Publikováno v:
Diabetes Research and Clinical Practice. 9:239-244
Ascorbic acid is required in the synthesis of collagen and is also an important anti-oxidant. In a previous study, plasma ascorbic acid concentration was found to be decreased in diabetic patients but there was no relationship with blood glucose leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04474c3be11512fe19631f01eb6354b0
https://doi.org/10.1016/0168-8227(90)90051-t
https://doi.org/10.1016/0168-8227(90)90051-t
Publikováno v:
Atherosclerosis. 168(2)
Diabetes is a major risk factor for atherosclerosis. Hyperglycemia is an underlying contributing factor; however, the mechanisms that mediate the vascular complications are not yet fully understood. In the present study, we provide evidence that elev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10b48496829c752be07c17a1c84b7a77
https://pubmed.ncbi.nlm.nih.gov/12801609
https://pubmed.ncbi.nlm.nih.gov/12801609
Autor:
Elizabeth J. Fisher, Dennis K. Yue, Susan V. McLennan, Carmela Capogreco, Scott Heffernan, John R. Turtle, Glynis R Ross
Publikováno v:
Diabetes. 38:257-261
It has been reported previously that the plasma concentration of ascorbic acid (AA) is reducedin streptozocin-induced diabetic rats and can be normalized by treatment with the aldose reductase inhibitor tolrestat. This study was designed to investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efb84f26ae3f8de9ff60bcb39db222ed
https://doi.org/10.2337/diab.38.2.257
https://doi.org/10.2337/diab.38.2.257