Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Elizabeth J. Coulson"'
Autor:
Lei Qian, Oliver Rawashdeh, Leda Kasas, Michael R. Milne, Nicholas Garner, Kornraviya Sankorrakul, Nicola Marks, Matthew W. Dean, Pu Reum Kim, Aanchal Sharma, Mark C. Bellingham, Elizabeth J. Coulson
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Sleep-disordered breathing is a risk factor for Alzheimer’s disease. Here the authors use mesopontine tegmentum lesion to model sleep disordered breathing in a mouse model of Alzheimer’s disease, and find that some features of the Alzheimer’s d
Externí odkaz:
https://doaj.org/article/22de7d61738d47849857fbf106da033e
Autor:
Jeremy Hunt, Elizabeth J. Coulson, Rajendram Rajnarayanan, Henrik Oster, Aleksandar Videnovic, Oliver Rawashdeh
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-21 (2022)
Abstract The use of animals as models of human physiology is, and has been for many years, an indispensable tool for understanding the mechanisms of human disease. In Parkinson’s disease, various mouse models form the cornerstone of these investiga
Externí odkaz:
https://doaj.org/article/39d0f9dfbaba41c3ac518ba6802b0e84
Autor:
Ying Xia, Eamonn Eeles, Jurgen Fripp, Donna Pinsker, Paul Thomas, Melissa Latter, Vincent Doré, Amir Fazlollahi, Pierrick Bourgeat, Victor L. Villemagne, Elizabeth J. Coulson, Stephen Rose
Publikováno v:
NeuroImage: Clinical, Vol 34, Iss , Pp 102992- (2022)
Dysfunction of the cholinergic basal forebrain (BF) neurotransmitter system, including cholinergic axon denervation of the cortex, plays an important role in cognitive decline and dementia. A validated method to directly quantify cortical cholinergic
Externí odkaz:
https://doaj.org/article/9c1dc99e779e4e3c99ae91c62c2c552d
Autor:
Yan Zhao, Elizabeth J. Coulson, Xingli Su, Junfeng Zhang, Baoyong Sha, Hao Xu, Yating Deng, Yulong Chen, Jian Cao, Yunpeng Wang, Shuang Wang
Publikováno v:
iScience, Vol 24, Iss 2, Pp 102043- (2021)
Summary: Major depression is a prevalent and long-lasting psychiatric illness with severe functional impairment and high suicide rate. We have previously shown that the ventrolateral orbital cortex (VLO) plays a key role in the stress responses in mi
Externí odkaz:
https://doaj.org/article/3ce11a93a0ef42a2b7fdc812f9950a13
Autor:
Nádia P. Gonçalves, Simin Mohseni, Marwa El Soury, Maj Ulrichsen, Mette Richner, Junhua Xiao, Rhiannon J. Wood, Olav M. Andersen, Elizabeth J. Coulson, Stefania Raimondo, Simon S. Murray, Christian B. Vægter
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Schwann cell reprogramming and differentiation are crucial prerequisites for neuronal regeneration and re-myelination to occur following injury to peripheral nerves. The neurotrophin receptor p75NTR has been identified as a positive modulator for Sch
Externí odkaz:
https://doaj.org/article/e730f8d20bf64674989c26d7b2e763df
Autor:
Tong Wang, Sally Martin, Tam H. Nguyen, Callista B. Harper, Rachel S. Gormal, Ramon Martínez-Mármol, Shanker Karunanithi, Elizabeth J. Coulson, Nick R. Glass, Justin J. Cooper-White, Bruno van Swinderen, Frédéric A. Meunier
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Signalling endosomes are known to be essential for neuronal survival. Here the authors show that, in cultured hippocampal neurons and live Drosophilalarval motor neurons, neuronal activity increases the retrograde flux of signalling endosomes, and th
Externí odkaz:
https://doaj.org/article/be42e86f725a40bf81556fbeac83c206
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Degeneration of basal forebrain cholinergic neurons (BFCNs) precedes hippocampal degeneration and pathological amyloid-beta (Aβ) accumulation, and underpins the development of cognitive dysfunction in sporadic Alzheimer’s disease (AD). We hypothes
Externí odkaz:
https://doaj.org/article/704920360754404cb02cc93e4f74a758
Autor:
Linda M. May, Victor Anggono, Helen M. Gooch, Se E. Jang, Dusan Matusica, Georg M. Kerbler, Frederic A. Meunier, Pankaj Sah, Elizabeth J. Coulson
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2017)
Alzheimer's disease is characterized by cognitive decline, neuronal degeneration, and the accumulation of amyloid-beta (Aβ). Although, the neurotoxic Aβ peptide is widely believed to trigger neuronal dysfunction and degeneration in Alzheimer's dise
Externí odkaz:
https://doaj.org/article/f7507f00ca724778ab8ecb390f70026e
Autor:
Tong Wang, Sally Martin, Tam H. Nguyen, Callista B. Harper, Rachel S. Gormal, Ramon Martínez-Mármol, Shanker Karunanithi, Elizabeth J. Coulson, Nick R. Glass, Justin J. Cooper-White, Bruno van Swinderen, Frédéric A. Meunier
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-1 (2016)
Nature Communications 7: Article number: 12976 doi: (2016); Published: 30 September 2016; Updated: 23 November 2016 In Fig. 3 of this Article, an image attribution was inadvertently omitted. The drawing of a Drosophila larva in Fig. 3a is reproduced
Externí odkaz:
https://doaj.org/article/630dbcd8152746cfa31d141ae271bd1e
Autor:
Ivana eGazova, Jan eLaczó, Eva eRubinova, Ivana eMokrisova, Eva eHyncicova, Ross eAndel, Martin eVyhnalek, Katerina eSheardova, Elizabeth J. Coulson, Jakub eHort
Publikováno v:
Frontiers in Aging Neuroscience, Vol 5 (2013)
Older age is associated with changes in the brain, including the medial temporal lobe, which may result in mild spatial navigation deficits, especially in allocentric navigation. The aim of the study was to characterize the profile of real-space allo
Externí odkaz:
https://doaj.org/article/bd37cc4a2fae468d9fc35e83ecb7bc72