Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Elizabeth J. Ampleford"'
Autor:
Jessica D. Gereige, Hanfei Xu, Victor E. Ortega, Michael H. Cho, Ming Liu, Phuwanat Sakornsakolpat, Edwin K. Silverman, Terri H. Beaty, Bruce E. Miller, Per Bakke, Amund Gulsvik, Craig P. Hersh, Jarrett D. Morrow, Elizabeth J. Ampleford, Gregory A. Hawkins, Eugene R. Bleecker, Deborah A. Meyers, Stephen P. Peters, Juan C. Celedón, Kelan Tantisira, Jiang Li, Josée Dupuis, George T. O'Connor
Publikováno v:
ERJ Open Research, Vol 8, Iss 2 (2022)
Introduction Bronchodilator response (BDR) is a measurement of acute bronchodilation in response to short-acting β2-agonists, with a heritability between 10 and 40%. Identifying genetic variants associated with BDR may lead to a better understanding
Externí odkaz:
https://doaj.org/article/d544fb2373e94b09b25c86585985dd8e
Autor:
Xingnan Li, Victor E. Ortega, Elizabeth J. Ampleford, R. Graham Barr, Stephanie A. Christenson, Christopher B. Cooper, David Couper, Mark T. Dransfield, Mei Lan K. Han, Nadia N. Hansel, Eric A. Hoffman, Richard E. Kanner, Eric C. Kleerup, Fernando J. Martinez, Robert Paine, Prescott G. Woodruff, Gregory A. Hawkins, Eugene R. Bleecker, Deborah A. Meyers, for the SPIROMICS Research Group
Publikováno v:
BMC Medical Genetics, Vol 19, Iss 1, Pp 1-10 (2018)
Abstract Background The aim of this study is to identify genetic loci associated with post-bronchodilator FEV1/FVC and FEV1, and develop a multi-gene predictive model for lung function in COPD. Methods Genome-wide association study (GWAS) of post-bro
Externí odkaz:
https://doaj.org/article/ed6ec0ac214248fa803e91c92095ce3f
Autor:
Loren C. Denlinger, Jerry A. Krishnan, Maria Pino-Yanes, Hengameh Raissy, Wayne J. Morgan, Manuela Cernadas, Michael D. Cabana, Daniel J. Jackson, J. Tod Olin, David Kantor, Julian Solway, Nicole Grossman, Elizabeth J. Ampleford, Jonathan M. Gaffin, Ronina Covar, Corey Cox, Michael E. Wechsler, James F. Chmiel, Elliot Israel, Kathleen C. Barnes, Steven R. White, Lisa Sullivan-Vedder, Stephen C. Lazarus, Fernando Holguin, Gregory A. Hawkins, Anne M. Fitzpatrick, Jason E. Lang, Vernon M. Chinchilli, Harsha Kumar, Jacqueline A. Pongracic, Max A. Seibold, Njira L Lugogo, Esteban G. Burchard, Angel C.Y. Mak, Fernando D. Martinez, Esther Herrera-Luis, Stephen P. Peters, James N. Moy, Lewis J. Smith, Victor E. Ortega, Sachin Baxi, Craig F. LaForce, Perdita Permaul, Marissa Hautpman, John J. Lima, Wanda Phipatanakul, Tarig Ali-Dinar, Michelle Daya, Juan Carlos Cardet, Kristie Ross, Nizar N. Jarjour, Christine A. Sorkness, Celeste Eng, Robert F. Lemanske, Susan J. Kunselman, Monica Kraft, Rachel G. Robison, Stanley J. Szefler, Deborah A. Meyers, Deborah Gentile, Mario Castro, Satria P Sajuthi, Dayna Long, Dave Mauger, Margee Louisias, Elizabeth Burke-Roberts, Donglei Hu, Ross E. Myers, Sally E. Wenzel, Kathryn V. Blake, Avraham Beigelman, Lakeia Wright, Mindy Benson, Leonard B. Bacharier, Eugene R. Bleecker, Wendy C. Moore, Emily DiMango, Loretta Que, Edward T. Naureckas, Lisa Bartnikas, William Sheehan
Publikováno v:
The Lancet. Child & adolescent health, vol 5, iss 12
Lancet Child Adolesc Health
Lancet Child Adolesc Health
BACKGROUND Pharmacogenetic studies in asthma cohorts, primarily made up of White people of European descent, have identified loci associated with response to inhaled beta agonists and corticosteroids (ICSs). Differences exist in how individuals from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34215da576a7d9499f7161c5b4881d4e
https://escholarship.org/uc/item/2x5116nm
https://escholarship.org/uc/item/2x5116nm
Autor:
Brian Rector, Chad Steele, Wendy C. Moore, Elizabeth J. Ampleford, Annette T. Hastie, Michelle Marks, Eugene R. Bleecker, Deborah A. Meyers
Publikováno v:
Thorax
Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) reportedly promotes, or conversely, resolves inflammation in asthma. In this study of TRAIL and cell receptors in sputum, bronchoalveolar lavage and biopsy from subjects in the Severe A
Autor:
Mizuki Nishino, Shwu Fan Ma, John D. Newell, Brian D. Hobbs, Purnema Madahar, Ani Manichaikul, Deborah A. Meyers, Vilmundur Gudnason, Tetsuro Araki, Gunnar Gudmundsson, Anna J. Podolanczuk, R. Graham Barr, David J. Lederer, George R. Washko, Victor E. Ortega, Justin M. Oldham, R. Gisli Jenkins, David A. Schwartz, Jerome I. Rotter, Gudny Eiriksdottir, Hanfei Xu, Stephen S. Rich, Louise V. Wain, Toby M. Maher, Imre Noth, Stephen P. Peters, Michael H. Cho, Tasha E. Fingerlin, Rachel K. Putman, Richard J. Allen, Hiroto Hatabu, Elizabeth J. Ampleford, George T. O'Connor, Wanda K. O'Neal, Josée Dupuis, Ivan O. Rosas, Gary M. Hunninghake, Nuno Rodrigues Zilhao Nogueira, Eugene R. Bleecker, Jennifer N. Nguyen, Richard Hubbard, Edwin K. Silverman
Publikováno v:
Am J Respir Crit Care Med
Rationale: Interstitial lung abnormalities (ILAs) are associated with the highest genetic risk locus for idiopathic pulmonary fibrosis (IPF); however, the extent to which there are unique associations among individuals with ILAs or additional overlap
Autor:
Wendy C. Moore, Elizabeth J. Ampleford, Eugene R. Bleecker, Gregory A. Hawkins, Stephen P. Peters, Kathleen C. Barnes, Victor E. Ortega, Deborah A. Meyers, Michelle Daya
Publikováno v:
Airway pharmacology and treatment.
Autor:
Rajesh Kumar, Meghan E. McGarry, Pedro C. Avila, Shannon Thyne, Ryan D. Hernandez, Max A. Seibold, Dara G. Torgerson, Jean G. Ford, Jose R. Rodriguez-Santana, Maria Pino-Yanes, Melissa L. Spear, Rocio Chapela, Donglei Hu, Neeta Thakur, Joshua Galanter, Angel C.Y. Mak, Adam Davis, Deborah A. Myers, Marquitta J. White, Celeste Eng, L. Keoki Williams, Emerita Brigino-Buenaventura, Albert M. Levin, Harold J. Farber, Eugene R. Bleecker, Stephen P. Peters, Andres Moreno Estrada, Denise Serebrisky, Scott Huntsman, Esteban G. Burchard, Sam S. Oh, Victor E. Ortega, Kelley Meade, William Rodriguez Cintron, Elizabeth J. Ampleford, Cheryl A. Winkler, Karla Sandoval, Michael A. LeNoir
Publikováno v:
The pharmacogenomics journal, vol 19, iss 3
The pharmacogenomics journal
The pharmacogenomics journal
Short-acting β2-adrenergic receptor agonists (SABAs) are the most commonly prescribed asthma medications worldwide. Response to SABAs is measured as bronchodilator drug response (BDR), which varies among racial/ethnic groups in the United States. Ho
Autor:
Jessica Lasky-Su, Ann Chen Wu, Michael J. McGeachie, Elizabeth J. Ampleford, Joanne E. Sordillo, Victor E. Ortega, Kelan G. Tantisira, Kirsten Voorhies, Amber Dahlin, Alberta L. Wang, Sharon M. Lutz, Rachel S. Kelly
Publikováno v:
Journal of Personalized Medicine, Vol 11, Iss 59, p 59 (2021)
Journal of Personalized Medicine
Volume 11
Issue 1
Journal of Personalized Medicine
Volume 11
Issue 1
An unaddressed and important issue is the role age plays in modulating response to short acting &beta
2-agonists in individuals with asthma. The objective of this study was to identify whether age modifies genetic associations of single nucleoti
2-agonists in individuals with asthma. The objective of this study was to identify whether age modifies genetic associations of single nucleoti
Autor:
Russell P. Bowler, Serpil C. Erzurum, Wendy C. Moore, Robert Paine, Suresh Garudadri, Xingnan Li, Sally E. Wenzel, Prescott G. Woodruff, John V. Fahy, Eric A. Hoffman, Elliot Israel, Jerry A. Krishnan, Loren C. Denlinger, Christopher B. Cooper, Nhlbi SubPopulations, Silva Kasela, Elizabeth J. Ampleford, Tuuli Lappalainen, MeiLan K. Han, Kristina L. Buschur, Charles Langelier, David Couper, Stephanie A. Christenson, Jenna Nguyen, Joe Zein, R. Graham Barr, Molly Martorella, InteRmediate Outcome Measures In Copd Study, Fernando J. Martinez, Nizar N. Jarjour, Srilaxmi Nerella, Jeffrey L. Curtis, Stephen P. Peters, Alejandro P. Comellas, Deborah A. Meyers, Victor E. Ortega, Nadia N. Hansel, Igor Barjaktarevic, Bruce D. Levy, Mario Castro, Gerard J. Criner, Merry-Lynn McDonald, Robert J. Kaner, Eugene R. Bleecker, Anu Pasanen
Publikováno v:
Genome medicine, vol 13, iss 1
Genome Medicine, Vol 13, Iss 1, Pp 1-17 (2021)
Genome Medicine
Genome Medicine, Vol 13, Iss 1, Pp 1-17 (2021)
Genome Medicine
Background The large airway epithelial barrier provides one of the first lines of defense against respiratory viruses, including SARS-CoV-2 that causes COVID-19. Substantial inter-individual variability in individual disease courses is hypothesized t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b11fe7cdc9fb2dff006e35e8372031
https://doi.org/10.1101/2020.10.01.20202820
https://doi.org/10.1101/2020.10.01.20202820
Autor:
Xiuqing Guo, Annette T. Hastie, Russell P. Bowler, Paul L. Auer, Elaine Cornell, Clary B. Clish, W. Craig Johnson, Alejandro P. Comellas, Michael Miller, Yongmei Liu, Stephen S. Rich, Debby Ngo, Claire M. Doerschuk, Victor E. Ortega, George J. Papanicolaou, Hong Dang, Alexander P. Reiner, Igor Barjaktarevic, Christine M. Freeman, Russell P. Tracy, Jerome I. Rotter, Kent D. Taylor, Peter Durda, Robert E. Gerszten, Lucas A. Gillenwater, Jeffrey L. Curtis, Claire Emson, Elizabeth J. Ampleford, Wassim W. Labaki, Katherine A. Pratte, Stephen P. Peters, Patricia V. Basta, Laura M. Raffield, Sean Jacobson, Gregory A. Hawkins, Julio Herrera, Wanda K. O'Neal, Brett Masters
Publikováno v:
Proteomics, vol 20, iss 12
Proteomics
Proteomics
Novel proteomics platforms, such as the aptamer-based SOMAscan platform, can quantify large numbers of proteins efficiently and cost-effectively and are rapidly growing in popularity. However, comparisons to conventional immunoassays remain underexpl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a116c4f47776cf969b22cab0dfee6d83
https://escholarship.org/uc/item/69r5f1rm
https://escholarship.org/uc/item/69r5f1rm