Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Elizabeth J Ryan"'
Autor:
Margaret eDunne, Ciara eRyan, Miriam eTosetto, Bláthnaid eNolan, Robert eGeraghty, Des C Winter, Ronan eO'Connell, John eHyland, Glen A Doherty, Kieran eSheahan, Elizabeth J Ryan, Jean M Fletcher
Publikováno v:
Frontiers in Oncology, Vol 6 (2016)
T cell infiltration into colorectal tumours has been shown to correlate with improved patient outcomes. However, more detailed information on the make-up and relationships between the infiltrating T cell subsets is lacking. We therefore correlated th
Externí odkaz:
https://doaj.org/article/5d7d01c0a28f4ce3aa6c15c8d6ade311
Publikováno v:
Frontiers in Oncology, Vol 5 (2015)
Upon binding their cognate receptors, ERα (ESR1) and ERβ (ESR2), estrogens activate intracellular signaling cascades that have important consequences for cellular behavior. Historically linked to carcinogenesis in reproductive organs, estrogens hav
Externí odkaz:
https://doaj.org/article/6c014af28fbf4ac29e7de0e143971d96
Autor:
Adriana J Michielsen, Andrew E Hogan, Joseph Marry, Miriam Tosetto, Fionnuala Cox, John M Hyland, Kieran D Sheahan, Diarmuid P O'Donoghue, Hugh E Mulcahy, Elizabeth J Ryan, Jacintha N O'Sullivan
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27944 (2011)
Inflammatory mediators in the tumour microenvironment promote tumour growth, vascular development and enable evasion of anti-tumour immune responses, by disabling infiltrating dendritic cells. However, the constituents of the tumour microenvironment
Externí odkaz:
https://doaj.org/article/1fa55522fd5248f3ba6a2700a7b5a095
Autor:
Ceara E Walsh, Elizabeth J Ryan, Cliona O'Farrelly, Lucy Golden-Mason, Oliver FitzGerald, Douglas J Veale, Barry Bresnihan, Ursula Fearon
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27182 (2011)
ObjectiveTNF inhibitors (TNFi) have revolutionised the treatment of rheumatoid arthritis (RA). Natural killer (NK) cells and Natural Killer Cell Receptor+ T (NKT) cells comprise important effector lymphocytes whose activity is tightly regulated throu
Externí odkaz:
https://doaj.org/article/26294b28a0c041b9b489ec5455461129
Autor:
Vanessa Zaiatz-Bittencourt, Fiona Jones, Miriam Tosetto, Caitriona Scaife, Gerard Cagney, Evan Jones, Glen A. Doherty, Elizabeth J. Ryan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The gut microbiota regulates chronic inflammation and has been implicated in the pathogenesis of a broad spectrum of disease including autoimmunity and cancer. Microbial short-chain fatty acids (SCFAs) e.g., butyrate have demonstrated immuno
Externí odkaz:
https://doaj.org/article/7ea9284ffa394ea0a9f11c4623309226
Autor:
Alana Nash, Elizabeth J. Ryan
Publikováno v:
Tumour Virus Research, Vol 14, Iss , Pp 200246- (2022)
Herpesviruses evade host immunity to establish persistent lifelong infection with dormant latent and replicative lytic phases. Epstein-Barr virus (EBV) and Kaposi's Sarcoma-associated virus (KSHV) are double-stranded DNA herpesviruses that encode com
Externí odkaz:
https://doaj.org/article/096a9d59725a453a9dc6801361b37cf8
Autor:
Alana Nash, Elizabeth J. Ryan
Publikováno v:
Animals, Vol 13, Iss 4, p 556 (2023)
The immune system of sea turtles is not completely understood. Sea turtles (as reptiles) bridge a unique evolutionary gap, being ectothermic vertebrates like fish and amphibians and amniotes like birds and mammals. Turtles are ectotherms; thus, their
Externí odkaz:
https://doaj.org/article/b2882936cfdf4dfe93ec9a6990f378f1
Autor:
Jayne Doherty, Neil O Morain, Roisin Stack, Miriam Tosetto, Rosanna Inzitiari, Sophie O Reilly, Lili Gu, Juliette Sheridan, Garret Cullen, Edel Mc Dermott, Maire Buckley, Gareth Horgan, Hugh Mulcahy, Margaret Walshe, Elizabeth J Ryan, Virginie Gautier, John Prostko, Edwin Frias, David Daghfal, Peter Doran, Colm O Morain, Glen A Doherty
Publikováno v:
Journal of Crohn's and Colitis.
Background and Aims Patients with inflammatory bowel disease [IBD] have an attenuated response to initial COVID-19 vaccination. We sought to characterize the impact of IBD and its treatment on responses after the third vaccine against SARS-CoV-2. Met
Autor:
Fernanda Zamboni, Guang Ren, Mario Culebras, John O'Driscoll, Jack O'Dwyer, Elizabeth J. Ryan, Maurice N. Collins
Curcumin is a known naturally occurring anti-inflammatory agent derived from turmeric, and it is commonly used as a herbal food supplement. Here, in order to overcome the inherent hydrophobicity of curcumin (Cur), polylactic acid (PLA) nanoparticles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84ebcda16a639bebf98e3aed26afe0e
Autor:
Garret Cullen, Neil O' Morain, Roisin Stack, Cillian De Gascun, Jayne Doherty, Elizabeth J. Ryan, Glen A. Doherty, Sean Fennessy
Publikováno v:
Alimentary Pharmacology & Therapeutics
Summary Background Poor immune responses are frequently observed in patients with inflammatory bowel disease (IBD) receiving established vaccines; risk factors include immunosuppressants and active disease. Aims To summarise available information reg