Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Elizabeth J Polvi"'
Autor:
Teresa R O'Meara, Matthew J O'Meara, Elizabeth J Polvi, M Reza Pourhaghighi, Sean D Liston, Zhen-Yuan Lin, Amanda O Veri, Andrew Emili, Anne-Claude Gingras, Leah E Cowen
Publikováno v:
PLoS Biology, Vol 17, Iss 7, p e3000358 (2019)
Hsp90 is a conserved molecular chaperone that assists in the folding and function of diverse cellular regulators, with a profound impact on biology, disease, and evolution. As a central hub of protein interaction networks, Hsp90 engages with hundreds
Externí odkaz:
https://doaj.org/article/b7738dbd09824335b714a967c9ef22d6
Autor:
Elizabeth J Polvi, Amanda O Veri, Zhongle Liu, Saif Hossain, Sabrina Hyde, Sang Hu Kim, Faiza Tebbji, Adnane Sellam, Robert T Todd, Jinglin L Xie, Zhen-Yuan Lin, Cassandra J Wong, Rebecca S Shapiro, Malcolm Whiteway, Nicole Robbins, Anne-Claude Gingras, Anna Selmecki, Leah E Cowen
Publikováno v:
PLoS Genetics, Vol 15, Iss 1, p e1007901 (2019)
Morphogenetic transitions are prevalent in the fungal kingdom. For a leading human fungal pathogen, Candida albicans, the capacity to transition between yeast and filaments is key for virulence. For the model yeast Saccharomyces cerevisiae, filamenta
Externí odkaz:
https://doaj.org/article/5f618964eca94d1e8ff2e9f2343fa25a
Autor:
Elizabeth J Polvi, Anna F Averette, Soo Chan Lee, Taeyup Kim, Yong-Sun Bahn, Amanda O Veri, Nicole Robbins, Joseph Heitman, Leah E Cowen
Publikováno v:
PLoS Genetics, Vol 12, Iss 10, p e1006350 (2016)
Fungal pathogens have evolved diverse strategies to sense host-relevant cues and coordinate cellular responses, which enable virulence and drug resistance. Defining circuitry controlling these traits opens new opportunities for chemical diversity in
Externí odkaz:
https://doaj.org/article/89815a9598c440b8a4db298d41a828d9
Autor:
Teresa R O'Meara, Amanda O Veri, Elizabeth J Polvi, Xinliu Li, Seyedeh Fereshteh Valaei, Stephanie Diezmann, Leah E Cowen
Publikováno v:
PLoS Genetics, Vol 12, Iss 6, p e1006142 (2016)
Candida albicans is a leading human fungal pathogen that causes life-threatening systemic infections. A key regulator of C. albicans stress response, drug resistance, morphogenesis, and virulence is the molecular chaperone Hsp90. Targeting Hsp90 prov
Externí odkaz:
https://doaj.org/article/ef8043648d084aaa88da390b0e6a57ef
Autor:
Tavia Caplan, Elizabeth J. Polvi, Jinglin L. Xie, Shoshana Buckhalter, Michelle D. Leach, Nicole Robbins, Leah E. Cowen
Publikováno v:
Cell Reports, Vol 23, Iss 8, Pp 2292-2298 (2018)
Summary: Candida albicans is a leading cause of death due to fungal infection. Treatment of systemic candidiasis often relies on echinocandins, which disrupt cell wall synthesis. Resistance is readily acquired via mutations in the drug target gene, F
Externí odkaz:
https://doaj.org/article/45f866759bfc4d2d8517cc9512a08484
Autor:
Erin B. Styles, Elizabeth J. Polvi
Publikováno v:
Teaching and Learning Inquiry. 10
The last class session of the academic term represents an excellent opportunity to solicit meaningful feedback from students who have just completed the course. To capitalize on the students’ first-hand knowledge of their own experiences with our c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9eca8a42753a0335a36f076d6f6c558e
https://doi.org/10.20343/teachlearninqu.10.28
https://doi.org/10.20343/teachlearninqu.10.28
Publikováno v:
Current Clinical Microbiology Reports. 8:139-151
Candida albicans is a common human fungal pathogen that was first described in the 1930s and is currently one of the major causes of invasive fungal infections, especially in immunocompromised patients. Since its first identification and association
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::caf07d8ea076fd90b773710efac02d57
https://doi.org/10.1007/s40588-021-00169-5
https://doi.org/10.1007/s40588-021-00169-5
Publikováno v:
J Biol Chem
Fungi inhabit extraordinarily diverse ecological niches, including the human body. Invasive fungal infections have a devastating impact on human health worldwide, killing ∼1.5 million individuals annually. The majority of these deaths are attributa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58bd2defa48b4ef6ceecf243f5c6fd25
https://doi.org/10.1074/jbc.rev120.013731
https://doi.org/10.1074/jbc.rev120.013731
Publikováno v:
Current Clinical Microbiology Reports. 9:9-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49124b77a5edd45edacd5326ae878316
https://doi.org/10.1007/s40588-022-00176-0
https://doi.org/10.1007/s40588-022-00176-0
Autor:
Shoshana Buckhalter, Tavia Caplan, Michelle D. Leach, Leah E. Cowen, Nicole Robbins, Elizabeth J. Polvi, Jinglin L. Xie
Publikováno v:
Cell Reports, Vol 23, Iss 8, Pp 2292-2298 (2018)
Summary: Candida albicans is a leading cause of death due to fungal infection. Treatment of systemic candidiasis often relies on echinocandins, which disrupt cell wall synthesis. Resistance is readily acquired via mutations in the drug target gene, F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0119269abfed920acb66919e56d71e53
http://www.sciencedirect.com/science/article/pii/S2211124718306430
http://www.sciencedirect.com/science/article/pii/S2211124718306430