Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Elizabeth J Myers"'
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175367 (2017)
Nicotine modulates multiple inflammatory responses in the lung through the nicotinic acetylcholine receptor subtype alpha7 (α7). Previously we reported that α7 modulates both the hematopoietic and epithelium responses in the lung to the bacterial i
Externí odkaz:
https://doaj.org/article/6184f33eb6f34ec1bbc690dc3c8a6092
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187773 (2017)
Cigarette smoking (CS) is a principal contributor to a spectrum of devastating lung diseases whose occurrence and severity may vary between individuals and not appear for decades after prolonged use. One explanation for the variability and delay in d
Externí odkaz:
https://doaj.org/article/b0fc045f62d24e86b4f4c7e7116b8bf0
Autor:
Diego A. López, Aleah Griffin, Lorena Moreno Aguilar, Cassandra Deering-Rice, Elizabeth J. Myers, Kristi J. Warren, Robert S. Welner, Anna E. Beaudin
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114365- (2024)
Summary: Here, we examine how prenatal inflammation shapes tissue function and immunity in the lung by reprogramming tissue-resident immune cells from early development. Maternal, but not fetal, type I interferon-mediated inflammation provokes expans
Externí odkaz:
https://doaj.org/article/75d547fead484bd6b82cb0c6c13f5eb6
Autor:
Elena Y Enioutina, Elizabeth J Myers, Petr Tvrdik, John R Hoidal, Scott W Rogers, Lorise C Gahring
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121128 (2015)
The nicotinic acetylcholine receptor alpha7 (α7) is expressed by neuronal and non-neuronal cells throughout the body. We examined the mechanisms of the lung inflammatory response to intranasal (i.n.) lipopolysaccharide (LPS) regulated by α7. This w
Externí odkaz:
https://doaj.org/article/1da234aa146a450c8b6f7638010dd6e6
Autor:
Lorise C Gahring, Elena Y Enioutina, Elizabeth J Myers, Gerald J Spangrude, Olga V Efimova, Todd W Kelley, Petr Tvrdik, Mario R Capecchi, Scott W Rogers
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57481 (2013)
How inflammatory responses are mechanistically modulated by nicotinic acetylcholine receptors (nAChR), especially by receptors composed of alpha7 (α7) subunits, is poorly defined. This includes a precise definition of cells that express α7 and how
Externí odkaz:
https://doaj.org/article/d1ef7d8b58034a3d89f3176649d9eed0
Autor:
Tom P. Huecksteadt, Elizabeth J. Myers, Samuel E. Aamodt, Shubhanshi Trivedi, Kristi J. Warren
Publikováno v:
Viruses, Vol 16, Iss 3, p 472 (2024)
SARS-CoV-2 infection has claimed just over 1.1 million lives in the US since 2020. Globally, the SARS-CoV-2 respiratory infection spread to 771 million people and caused mortality in 6.9 million individuals to date. Much of the early literature showe
Externí odkaz:
https://doaj.org/article/e14319279575450282fa99995817391d
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 315:L553-L562
Eosinophilia (EOS) is an important component of airway inflammation and hyperresponsiveness in allergic reactions including those leading to asthma. Although cigarette smoking (CS) is a significant contributor to long-term adverse outcomes in these l
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology
Nicotine acts as a potent modulator of normal cellular responses through the nicotinic acetylcholine receptor subtype alpha7. In a mouse genetic model of alpha7 receptor dysfunction, alpha7E260A:G, 85 percent of 18 month-old mice exhibit an age-assoc
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Nicotine of unprecedented concentrations and purity is being inhaled by those using commercially available electronic nicotine delivery systems (ENDS). The consequences of this route of self-administration on the immunological response to inhaled all
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187773 (2017)
PLoS ONE
PLoS ONE
Cigarette smoking (CS) is a principal contributor to a spectrum of devastating lung diseases whose occurrence and severity may vary between individuals and not appear for decades after prolonged use. One explanation for the variability and delay in d