Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Elizabeth J, Soilleux"'
Autor:
Elizabeth J. Soilleux, Daniel T. Rodgers, Jinlong J. Situ, Shelley C. Evans, Venkata N. Konda, Han-Chieh Yang, Jianxiong Pang, Isabella Gilbey Smith, Pete Rajesh, Maryam Salimi, Soo Weei Ng, Julia Jones, Jodi L. Miller, Rachel Etherington, Margaret Ashton-Key, Graham Ogg
Publikováno v:
Diagnostics, Vol 14, Iss 22, p 2479 (2024)
Background/Objectives: T-cell lymphomas are often histologically indistinguishable from benign T-cell infiltrates, and diagnosis typically relies on slow, complex, and expensive multiplexed PCR reactions, requiring significant training and experience
Externí odkaz:
https://doaj.org/article/e6a2c6b212a24342a8501376bc0f3ffe
Autor:
Mark J Arends, Andrew Robinson, Kishore Gopalakrishnan, Eve Fryer, Betania Mahler-Araujo, Sonali Natu, Elizabeth J Soilleux, Gerald Langman, Kathryn J Kirkwood, EMYR W BENBOW, Caroline A Hughes, Yee Wah Tsang, James Denholm, Benjamin A Schreiber, Florian Jaeckle, Mike N Wicks, Tim S Bracey, James Y H Chan, Lorant Farkas, Raymond F T McMahon, Khun La Win Myint, Ashraf Sanduka, Katharine A Sheppard
Publikováno v:
BMJ Open Gastroenterology, Vol 11, Iss 1 (2024)
Objective Coeliac disease (CD) diagnosis generally depends on histological examination of duodenal biopsies. We present the first study analysing the concordance in examination of duodenal biopsies using digitised whole-slide images (WSIs). We furthe
Externí odkaz:
https://doaj.org/article/f255879a5c044f40853761bffd7965cc
Autor:
Anna Fowler, Michael FitzPatrick, Aberami Shanmugarasa, Amro Sayed Fadel Ibrahim, Hannah Kockelbergh, Han-Chieh Yang, Amelia Williams-Walker, Kim Ngan Luu Hoang, Shelley Evans, Nicholas Provine, Paul Klenerman, Elizabeth J. Soilleux
Publikováno v:
Biomolecules, Vol 13, Iss 12, p 1707 (2023)
Coeliac disease (CeD) is a T-cell mediated enteropathy triggered by dietary gluten which remains substantially under-diagnosed around the world. The diagnostic gold-standard requires histological assessment of intestinal biopsies taken at endoscopy w
Externí odkaz:
https://doaj.org/article/965f330abc59469c9e7f54cb7024adb4
Autor:
Liam D. Cassidy, Andrew R. J. Young, Christopher N. J. Young, Elizabeth J. Soilleux, Edward Fielder, Bettina M. Weigand, Anthony Lagnado, Rebecca Brais, Nicholas T. Ktistakis, Kimberley A. Wiggins, Katerina Pyrillou, Murray C. H. Clarke, Diana Jurk, Joao F. Passos, Masashi Narita
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Autophagy declines with age, yet it is unclear if restoration of autophagy extends lifespan. Here, the authors demonstrate in murine models that the inhibition of Atg5 induces ageing phenotypes and reduces lifespan, whilst autophagy restoration parti
Externí odkaz:
https://doaj.org/article/08d9c43fad6f4fa996ca4382c883b9dc
Autor:
Hannah Kockelbergh, Shelley Evans, Tong Deng, Ella Clyne, Anna Kyriakidou, Andreas Economou, Kim Ngan Luu Hoang, Stephen Woodmansey, Andrew Foers, Anna Fowler, Elizabeth J. Soilleux
Publikováno v:
Diagnostics, Vol 12, Iss 5, p 1222 (2022)
Measuring immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 19 (COVID-19), can rely on antibodies, reactive T cells and other factors, with T-cell-mediated responses appearing to have
Externí odkaz:
https://doaj.org/article/a605ddd53774465089836aebf8546fc6
Autor:
Yuri Hirayama, Natasha Faye Daniels, Shelley Evans, David Clarke, Stephenie Purvis, Charlotte Oliver, Stephen Woodmansey, Joy Staniforth, Elizabeth J. Soilleux
Publikováno v:
Diagnostics, Vol 11, Iss 9, p 1703 (2021)
A high prevalence of hepatic pathology (in 17 of 19 cases) was reported in post-mortem (PM) examinations of COVID-19 patients, undertaken between March 2020 and February 2021 by a single autopsy pathologist in two English Coronial jurisdictions. The
Externí odkaz:
https://doaj.org/article/1e18667d0ba14c07b66c97fa0c3e09c2
Autor:
Charlotte J. Imianowski, Sarah K. Whiteside, Teresa Lozano, Alexander C. Evans, Jayme D. Benson, Christina J.F. Courreges, Firas Sadiyah, Colleen M. Lau, Nordin D. Zandhuis, Francis M. Grant, Martijn J. Schuijs, Panagiota Vardaka, Paula Kuo, Elizabeth J. Soilleux, Jie Yang, Joseph C. Sun, Tomohiro Kurosaki, Klaus Okkenhaug, Timotheus Y.F. Halim, Rahul Roychoudhuri
Publikováno v:
Journal of Experimental Medicine. 219
Natural killer (NK) cells are critical to immune surveillance against infections and cancer. Their role in immune surveillance requires that NK cells are present within tissues in a quiescent state. Mechanisms by which NK cells remain quiescent in ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fecacc7251e7923f5e10f96d7c256dc8
https://doi.org/10.1084/jem.20211476
https://doi.org/10.1084/jem.20211476
Autor:
Yikun Yao, Ping Du Jiang, Brittany N. Chao, Deniz Cagdas, Satoshi Kubo, Arasu Balasubramaniyam, Yu Zhang, Bella Shadur, Adeeb NaserEddin, Les R. Folio, Benjamin Schwarz, Eric Bohrnsen, Lixin Zheng, Matthew Lynberg, Simone Gottlieb, Michael A. Leney-Greene, Ann Y. Park, Ilhan Tezcan, Ali Akdogan, Rahsan Gocmen, Sevgen Onder, Avi Rosenberg, Elizabeth J. Soilleux, Errin Johnson, Peter K. Jackson, Janos Demeter, Samuel D. Chauvin, Florian Paul, Matthias Selbach, Haydar Bulut, Menna R. Clatworthy, Zewen K. Tuong, Hanlin Zhang, Benjamin J. Stewart, Catharine M. Bosio, Polina Stepensky, Simon Clare, Sundar Ganesan, John C. Pascall, Oliver Daumke, Geoffrey W. Butcher, Andrew J. McMichael, Anna Katharina Simon, Michael J. Lenardo
Inborn errors of immunity (IEIs) unveil regulatory pathways of human immunity. We describe a new IEI caused by mutations in the GTPase of the immune-associated protein 6 (GIMAP6) gene in patients with infections, lymphoproliferation, autoimmunity, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e875cafd6e83da3c9610e843fba1a87e
http://edoc.mdc-berlin.de/21629/1/21629oa.pdf
http://edoc.mdc-berlin.de/21629/1/21629oa.pdf
Autor:
Georgina S. F. Anderson, Jose Ballester-Beltran, George Giotopoulos, Jose A. Guerrero, Sylvanie Surget, James C. Williamson, Tsz So, David Bloxham, Anna Aubareda, Ryan Asby, Ieuan Walker, Lesley Jenkinson, Elizabeth J. Soilleux, James P. Roy, Ana Teodósio, Catherine Ficken, Leah Officer-Jones, Sara Nasser, Sheri Skerget, Jonathan J. Keats, Peter Greaves, Yu-Tzu Tai, Kenneth C. Anderson, Marion MacFarlane, James E. Thaventhiran, Brian J. P. Huntly, Paul J. Lehner, Michael A. Chapman
Publikováno v:
Blood. 139(16)
The accessibility of cell surface proteins makes them tractable for targeting by cancer immunotherapy, but identifying suitable targets remains challenging. Here we describe plasma membrane profiling of primary human myeloma cells to identify an unpr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f883fef44de4c75033f62b27c05299
https://pubmed.ncbi.nlm.nih.gov/35446380
https://pubmed.ncbi.nlm.nih.gov/35446380
Autor:
Michael E Reschen, Kyle J Gaulton, Da Lin, Elizabeth J Soilleux, Andrew J Morris, Susan S Smyth, Christopher A O'Callaghan
Publikováno v:
PLoS Genetics, Vol 11, Iss 4, p e1005061 (2015)
Genome-wide association studies (GWAS) have identified over 40 loci that affect risk of coronary artery disease (CAD) and the causal mechanisms at the majority of loci are unknown. Recent studies have suggested that many causal GWAS variants influenc
Externí odkaz:
https://doaj.org/article/e4ab5a295c9c4824b1024f6c1da003d8