Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Elizabeth Ilett"'
Autor:
Timothy Kottke, Jason Tonne, Laura Evgin, Christopher B. Driscoll, Jacob van Vloten, Victoria A. Jennings, Amanda L. Huff, Brady Zell, Jill M. Thompson, Phonphimon Wongthida, Jose Pulido, Matthew R. Schuelke, Adel Samson, Peter Selby, Elizabeth Ilett, Mark McNiven, Lewis R. Roberts, Mitesh J. Borad, Hardev Pandha, Kevin Harrington, Alan Melcher, Richard G. Vile
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Oncolytic viruses, such as vesicular stomatitis virus (VSV), are a promising class of cancer therapeutics. Here the authors report that a mutation in the CSDE1 gene renders cancer cells resistant to VSV replication and oncolysis, but a mutation-deriv
Externí odkaz:
https://doaj.org/article/0057781c39ce43a79a6659f6e847a415
Autor:
Julia V. Cockle, Anke Brüning-Richardson, Karen J. Scott, Jill Thompson, Timothy Kottke, Ewan Morrison, Azam Ismail, Angel M. Carcaboso, Ailsa Rose, Peter Selby, Joe Conner, Susan Picton, Susan Short, Richard Vile, Alan Melcher, Elizabeth Ilett
Publikováno v:
Molecular Therapy: Oncolytics, Vol 5, Iss C, Pp 75-86 (2017)
Pediatric high-grade glioma (pHGG) and diffuse intrinsic pontine glioma (DIPG) are invasive tumors with poor survival. Oncolytic virotherapy, initially devised as a direct cytotoxic treatment, is now also known to act via immune-mediated mechanisms.
Externí odkaz:
https://doaj.org/article/6daa5830e2af4d63a0235f4c00e305f7
Publikováno v:
Cancers, Vol 12, Iss 11, p 3219 (2020)
Oncolytic virotherapy (OVT) has received significant attention in recent years, especially since the approval of talimogene Laherparepvec (T-VEC) in 2015 by the Food and Drug administration (FDA). Mechanistic studies of oncolytic viruses (OVs) have r
Externí odkaz:
https://doaj.org/article/1171ea491fb447f396daf015508bb2f8
Autor:
Angela S. Attwood, Kayleigh E. Easey, Michael N. Dalili, Andrew L. Skinner, Andy Woods, Lana Crick, Elizabeth Ilett, Ian S. Penton-Voak, Marcus R. Munafò
Publikováno v:
Royal Society Open Science, Vol 4, Iss 5 (2017)
High trait anxiety has been associated with detriments in emotional face processing. By contrast, relatively little is known about the effects of state anxiety on emotional face processing. We investigated the effects of state anxiety on recognition
Externí odkaz:
https://doaj.org/article/79bb73aaa0f349fb9d396299e74a151c
Autor:
Tim Kottke, Kevin G Shim, Vanesa Alonso-Camino, Shane Zaidi, Rosa Maria Diaz, Jose Pulido, Jill Thompson, Karishma R Rajani, Laura Evgin, Elizabeth Ilett, Hardev Pandha, Kevin Harrington, Peter Selby, Alan Melcher, Richard Vile
Publikováno v:
Molecular Therapy: Oncolytics, Vol 3, Iss C (2016)
We showed previously that therapy with Vesicular Stomatitis Virus (VSV) expressing tumor-associated proteins eradicates established tumors. We show here that when cellular cDNA were cloned into VSV which retained their own poly-A signal, viral specie
Externí odkaz:
https://doaj.org/article/7f02966617734e6faf39d13cde720b8b
Autor:
Ramtin Zargari Marandi, Mette Jørgensen, Emma Elizabeth Ilett, Jens Christian Nørgaard, Marc Noguera-Julian, Roger Paredes, Jens D. Lundgren, Henrik Sengeløv, Cameron Ross MacPherson
Publikováno v:
Cells, Vol 11, Iss 24, p 4089 (2022)
Gut microbiota is thought to influence host responses to allogeneic hematopoietic stem cell transplantation (aHSCT). Recent evidence points to this post-transplant for acute graft-versus-host disease (aGvHD). We asked whether any such association mig
Externí odkaz:
https://doaj.org/article/4d2c300b8e78426195ee2cf9f8ad40e0
Autor:
Jens Christian Nørgaard, Mette Jørgensen, Kasper Sommerlund Moestrup, Emma Elizabeth Ilett, Adrian Gabriel Zucco, Ramtin Z Marandi, Marc Noguera Julian, Roger Paredes, Jens D Lundgren, Henrik Sengeløv, Cameron MacPherson
Publikováno v:
The Journal of Infectious Diseases.
Antibiotic-resistant bacterial infections are increasingly an issue in allogenic hematopoietic stem cell transplant patients. How antibiotic treatment impacts antibiotic resistance in the human gut microbiome remains poorly understood in vivo. Here,
Autor:
Emily P. Slater, Elisabeth Maurer, Carsten Palnæs Hansen, Ulrich Knigge, Andreas Kjaer, Detlef K. Bartsch, Seppo W. Langer, Emma Elizabeth Ilett, Peter H. Kann, Dominik Wiese, Norman Gercke, Mikkel Andreassen, Marianne Klose, Birgitte Federspiel
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 104:6129-6138
IntroductionDiagnosis and pathological classification of insulinomas are challenging.AimTo characterize localization of tumors, surgery outcomes, and histopathology in patients with insulinoma.MethodsPatients with surgically resected sporadic insulin
Autor:
Kevin J. Harrington, Reuben S. Harris, Amy M. Molan, Timothy Kottke, Jill Thompson, Peter Selby, Karen Kaluza Smith, Amanda L. Huff, Richard G. Vile, Christopher B. Driscoll, Elizabeth Ilett, Laura Evgin, Phonphimon Wongthida, Matthew C. Coffey, Hardev Pandha, Kevin G. Shim, Alan Melcher, Matthew Schuelke, Jose S. Pulido
Publikováno v:
Cancer Immunol Res
Antitumor T-cell responses raised by first-line therapies such as chemotherapy, radiation, tumor cell vaccines, and viroimmunotherapy tend to be weak, both quantitatively (low frequency) and qualitatively (low affinity). We show here that T cells tha
Autor:
Adel Samson, Matthew C. Coffey, Gina B. Scott, Elizabeth Ilett, Munitta Muthana, Karen Scott, Michelle A. Lawson, Babatunde O. Oyajobi, Jenny Down, Christy Ralph, Sancha King, Victoria A. Jennings, Basem Askar, Alan Melcher, Fiona Errington-Mais, Louise M. E. Müller, Christopher Parrish, Gemma Migneco, Emma West, Gordon Cook
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
BackgroundMultiple myeloma (MM) remains an incurable disease and oncolytic viruses offer a well-tolerated addition to the therapeutic arsenal. Oncolytic reovirus has progressed to phase I clinical trials and its direct lytic potential has been extens