Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Elizabeth Hinde"'
Autor:
Shaban B. Sulejman, Niken Priscilla, Lukas Wesemann, Wendy S. L. Lee, Jieqiong Lou, Elizabeth Hinde, Timothy J. Davis, Ann Roberts
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Many image processing operations involve the modification of the spatial frequency content of images. Here we demonstrate object-plane spatial frequency filtering utilizing the angular sensitivity of a commercial spectral bandstop filter. Th
Externí odkaz:
https://doaj.org/article/104d7a92d98a46a88d36bd2d2036b62a
Autor:
Elizabeth Hinde, Linda L. Blackall, Madeleine J. H. van Oppen, Douglas R. Brumley, Sarah Jane Tsang Min Ching, Iromi Wanigasuriya, Pranali Deore
Publikováno v:
Microbiology Australia, Vol 43, Iss 1, Pp 22-27 (2022)
Corals and their photosynthetic endosymbiotic algae (Symbiodiniaceae) produce a strong autofluorescent signal that spans the visible to near-infrared (NIR) spectrum. However, this broad- spectrum emission hinders the use of fluorescence in situ hybri
Externí odkaz:
https://doaj.org/article/80be792b34df4e89afde33b3ed42e2be
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Transcription factors (TFs) are core players in the control of gene expression, evolutionarily selected to recognise a subset of specific DNA sequences and nucleate the recruitment of the transcriptional machinery. How TFs assemble and move
Externí odkaz:
https://doaj.org/article/8593dee152d94a6781418e818c37be23
Autor:
Lukas Wesemann, Jon Rickett, Jingchao Song, Jieqiong Lou, Elizabeth Hinde, Timothy J. Davis, Ann Roberts
Publikováno v:
Light: Science & Applications, Vol 10, Iss 1, Pp 1-6 (2021)
Abstract The ability to visualise transparent objects such as live cells is central to understanding biological processes. Here we experimentally demonstrate a novel nanostructured coverslip that converts phase information to high-contrast intensity
Externí odkaz:
https://doaj.org/article/1c6c992733834e2a93cf2f722318c1e8
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
53BP1 is a crucial factor involved in double strand break repair which blocks DNA end resection affecting DNA repair pathway choice. Here the authors reveal by live cell nuclear architecture analysis the spatiotemporal dynamics of 53BP1 oligomerizati
Externí odkaz:
https://doaj.org/article/e48284b5b37449da83b9cc38e07d02f1
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
A DNA double-strand break (DSB) takes place in the context of chromatin, and there is increasing evidence for chromatin structure to play a functional role in DSB signaling and repair. Thus, there is an emerging need for quantitative microscopy metho
Externí odkaz:
https://doaj.org/article/b997f00aaa054f1c9bbf80033855aef1
Autor:
Stacey N. Keenan, William De Nardo, Jieqiong Lou, Ralf B. Schittenhelm, Magdalene K. Montgomery, James G. Granneman, Elizabeth Hinde, Matthew J. Watt
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100016- (2021)
Perilipin 5 (PLIN5) is a lipid-droplet-associated protein that coordinates intracellular lipolysis in highly oxidative tissues and is thought to regulate lipid metabolism in response to phosphorylation by protein kinase A (PKA). We sought to identify
Externí odkaz:
https://doaj.org/article/fa5a9be0f3824de49839e18d04e01713
Publikováno v:
Data in Brief, Vol 30, Iss , Pp 105401- (2020)
The nanometer spacing between nucleosomes throughout global chromatin organisation modulates local DNA template access, and through continuous dynamic rearrangements, regulates genome function [1]. However, given that nucleosome packaging occurs on a
Externí odkaz:
https://doaj.org/article/e7a62209a8504884bab49b87bdc8c221
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0233583 (2020)
Mutations that cause Huntington's Disease involve a polyglutamine (polyQ) sequence expansion beyond 35 repeats in exon 1 of Huntingtin. Intracellular inclusion bodies of mutant Huntingtin protein are a key feature of Huntington's disease brain pathol
Externí odkaz:
https://doaj.org/article/3a2c56c580324d5480cfe8000dc60143
Autor:
Elizabeth Hinde, Elvis Pandžić, Zhengmin Yang, Ivan H. W. Ng, David A. Jans, Marie A. Bogoyevitch, Enrico Gratton, Katharina Gaus
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Oligomerisation of transcription factors regulates their translocation into the nucleus, DNA binding affinity and sequence specificity. Here, Hinde et al. present a microscopy analysis, pair correlation of molecular brightness, that tracks the molecu
Externí odkaz:
https://doaj.org/article/db96e5c3576b42e9b2eda1827f25dcda