Risk factors for health impairments in children after hospitalization for acute COVID-19 or MIS-C

Autor: Aline B. Maddux, Cameron C. Young, Suden Kucukak, Laura D. Zambrano, Margaret M. Newhams, Caitlin K. Rollins, Natasha B. Halasa, Shira J. Gertz, Elizabeth H. Mack, Stephanie Schwartz, Michele Kong, Laura L. Loftis, Katherine Irby, Courtney M. Rowan, Keiko M. Tarquinio, Matt S. Zinter, Hillary Crandall, Natalie Z. Cvijanovich, Jennifer E. Schuster, Julie C. Fitzgerald, Mary A. Staat, Charlotte V. Hobbs, Ryan A. Nofziger, Steven Shein, Heidi Flori, Melissa L. Cullimore, Brandon M. Chatani, Emily R. Levy, Katri V. Typpo, Janet R. Hume, Angela P. Campbell, Adrienne G. Randolph, the Overcoming COVID-19 Investigators, Meghan Murdock, Heather Kelley, Candice Colston, Mary Glas Gaspers, Ronald C. Sanders, Emily Port, Rachel Mansour, Sara Shankman, Kaitlin Jones, Caitlin Rollins, Tanya Novak, Janet Chou, Mary Beth Son, Julia Clarke, Brooke Sens, Eve Listerud, Sabrina Chen, Kasey Stewart, Heidi R. Flori, Mary K. Dahmer, Supriya Behl, Noelle M. Drapeau, Lora Martin, Lacy Malloch, Maygan Martin, Kayla Patterson, Cameron Sanders, Kengo Inagaki, Sarah McGraw, Anita Dhanrajani, Abigail Kietzman, Shannon Hill, Russell J. McCulloh, Stephanie P. Schwartz, Tracie C. Walker, Mary Allen Staat, Rajashri Rasal, Ryan Burnett, Jenny Bush, Meena Golcha, Laura Stewart, Krow Ampofo, Manish M. Patel, Leora R. Feldstein, Mark W. Tenforde, Ashley M. Jackson, Angela Campbell

Publikováno v: Frontiers in Pediatrics, Vol 11 (2023)

ObjectiveTo identify risk factors for persistent impairments after pediatric hospitalization for acute coronavirus disease 2019 (COVID-19) or multisystem inflammatory syndrome in children (MIS-C) during the SARS-CoV-2 pandemic.MethodsAcross 25 U.S. O

Externí odkaz: https://doaj.org/article/1e2f7cbc16d047dbab50b8aeff084f5e

The Notch1/CD22 signaling axis disrupts Treg function in SARS-CoV-2–associated multisystem inflammatory syndrome in children

Autor: Mehdi Benamar, Qian Chen, Janet Chou, Amélie M. Julé, Rafik Boudra, Paola Contini, Elena Crestani, Peggy S. Lai, Muyun Wang, Jason Fong, Shira Rockwitz, Pui Lee, Tsz Man Fion Chan, Ekin Zeynep Altun, Eda Kepenekli, Elif Karakoc-Aydiner, Ahmet Ozen, Perran Boran, Fatih Aygun, Pinar Onal, Ayse Ayzit Kilinc Sakalli, Haluk Cokugras, Metin Yusuf Gelmez, Fatma Betul Oktelik, Esin Aktas Cetin, Yuelin Zhong, Maria Lucia Taylor, Katherine Irby, Natasha B. Halasa, Elizabeth H. Mack, Overcoming COVID-19 Investigators, Sara Signa, Ignazia Prigione, Marco Gattorno, Nicola Cotugno, Donato Amodio, Raif S. Geha, Mary Beth Son, Jane Newburger, Pankaj B. Agrawal, Stefano Volpi, Paolo Palma, Ayca Kiykim, Adrienne G. Randolph, Gunnur Deniz, Safa Baris, Raffaele De Palma, Klaus Schmitz-Abe, Louis-Marie Charbonnier, Lauren A. Henderson, Talal A. Chatila

Publikováno v: The Journal of Clinical Investigation, Vol 133, Iss 1 (2023)

Multisystem inflammatory syndrome in children (MIS-C) evolves in some pediatric patients following acute infection with SARS-CoV-2 by hitherto unknown mechanisms. Whereas acute-COVID-19 severity and outcomes were previously correlated with Notch4 exp

Externí odkaz: https://doaj.org/article/a39c807bcee64be782682857c935eead

Author Correction: Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C

Autor: Juanjie Tang, Tanya Novak, Julian Hecker, Gabrielle Grubbs, Fatema Tuz Zahra, Lorenza Bellusci, Sara Pourhashemi, Janet Chou, Kristin Moffitt, Natasha B. Halasa, Stephanie P. Schwartz, Tracie C. Walker, Keiko M. Tarquinio, Matt S. Zinter, Mary A. Staat, Shira J. Gertz, Natalie Z. Cvijanovich, Jennifer E. Schuster, Laura L. Loftis, Bria M. Coates, Elizabeth H. Mack, Katherine Irby, Julie C. Fitzgerald, Courtney M. Rowan, Michele Kong, Heidi R. Flori, Aline B. Maddux, Steven L. Shein, Hillary Crandall, Janet R. Hume, Charlotte V. Hobbs, Adriana H. Tremoulet, Chisato Shimizu, Jane C. Burns, Sabrina R. Chen, Hye Kyung Moon, Christoph Lange, Adrienne G. Randolph, Surender Khurana

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)

Externí odkaz: https://doaj.org/article/a92960f10907461dbc77a531a0efcff5

BNT162b2 Protection against the Omicron Variant in Children and Adolescents

Autor: Ashley M, Price, Samantha M, Olson, Margaret M, Newhams, Natasha B, Halasa, Julie A, Boom, Leila C, Sahni, Pia S, Pannaraj, Katherine, Irby, Katherine E, Bline, Aline B, Maddux, Ryan A, Nofziger, Melissa A, Cameron, Tracie C, Walker, Stephanie P, Schwartz, Elizabeth H, Mack, Laura, Smallcomb, Jennifer E, Schuster, Charlotte V, Hobbs, Satoshi, Kamidani, Keiko M, Tarquinio, Tamara T, Bradford, Emily R, Levy, Kathleen, Chiotos, Samina S, Bhumbra, Natalie Z, Cvijanovich, Sabrina M, Heidemann, Melissa L, Cullimore, Shira J, Gertz, Bria M, Coates, Mary A, Staat, Matt S, Zinter, Michele, Kong, Brandon M, Chatani, Janet R, Hume, Katri V, Typpo, Mia, Maamari, Heidi R, Flori, Mark W, Tenforde, Laura D, Zambrano, Angela P, Campbell, Manish M, Patel, Adrienne G, Randolph

Publikováno v: New England Journal of Medicine. 386:1899-1909

Spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.529 (omicron) variant, which led to increased U.S. hospitalizations for coronavirus disease 2019 (Covid-19), generated concern about immune evasion and the duration of p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad8b0190ab82599530302d41b6be7f56
https://doi.org/10.1056/nejmoa2202826

Effectiveness of Maternal Vaccination with mRNA COVID-19 Vaccine During Pregnancy Against COVID-19–Associated Hospitalization in Infants Aged <6 Months — 17 States, July 2021–January 2022

Autor: Natasha B, Halasa, Samantha M, Olson, Mary A, Staat, Margaret M, Newhams, Ashley M, Price, Julie A, Boom, Leila C, Sahni, Melissa A, Cameron, Pia S, Pannaraj, Katherine E, Bline, Samina S, Bhumbra, Tamara T, Bradford, Kathleen, Chiotos, Bria M, Coates, Melissa L, Cullimore, Natalie Z, Cvijanovich, Heidi R, Flori, Shira J, Gertz, Sabrina M, Heidemann, Charlotte V, Hobbs, Janet R, Hume, Katherine, Irby, Satoshi, Kamidani, Michele, Kong, Emily R, Levy, Elizabeth H, Mack, Aline B, Maddux, Kelly N, Michelson, Ryan A, Nofziger, Jennifer E, Schuster, Stephanie P, Schwartz, Laura, Smallcomb, Keiko M, Tarquinio, Tracie C, Walker, Matt S, Zinter, Suzanne M, Gilboa, Kara N, Polen, Angela P, Campbell, Adrienne G, Randolph, Manish M, Patel, Mia, Maamari

Publikováno v: MMWR. Morbidity and Mortality Weekly Report. 71:264-270

COVID-19 vaccination is recommended for persons who are pregnant, breastfeeding, trying to get pregnant now, or who might become pregnant in the future, to protect them from COVID-19.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166d4c2ef6c3ae49e40f0ce81154b3bc
https://doi.org/10.15585/mmwr.mm7107e3