Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Elizabeth Grass"'
Autor:
Jawan W. Abdulrahim, Lydia Coulter Kwee, Elizabeth Grass, Ilene C. Siegler, Redford Williams, Ravi Karra, William E. Kraus, Simon G. Gregory, Svati H. Shah
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 21 (2019)
Background DNA methylation is implicated in many chronic diseases and may contribute to mortality. Therefore, we conducted an epigenome‐wide association study (EWAS) for all‐cause mortality with whole‐transcriptome data in a cardiovascular coho
Externí odkaz:
https://doaj.org/article/0220683bd3ac4944a048c609bacd8f55
Autor:
Cavin K Ward-Caviness, Lucas M Neas, Colette Blach, Carol S Haynes, Karen LaRocque-Abramson, Elizabeth Grass, Z Elaine Dowdy, Robert B Devlin, David Diaz-Sanchez, Wayne E Cascio, Marie Lynn Miranda, Simon G Gregory, Svati H Shah, William E Kraus, Elizabeth R Hauser
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173880 (2017)
Air pollution is a worldwide contributor to cardiovascular disease mortality and morbidity. Traffic-related air pollution is a widespread environmental exposure and is associated with multiple cardiovascular outcomes such as coronary atherosclerosis,
Externí odkaz:
https://doaj.org/article/449a19c615f143e8bb8696bfce5e3e69
Autor:
Cavin K Ward-Caviness, Lucas M Neas, Colette Blach, Carol S Haynes, Karen LaRocque-Abramson, Elizabeth Grass, Elaine Dowdy, Robert B Devlin, David Diaz-Sanchez, Wayne E Cascio, Marie Lynn Miranda, Simon G Gregory, Svati H Shah, William E Kraus, Elizabeth R Hauser
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152670 (2016)
There is a growing literature indicating that genetic variants modify many of the associations between environmental exposures and clinical outcomes, potentially by increasing susceptibility to these exposures. However, genome-scale investigations of
Externí odkaz:
https://doaj.org/article/64eba910f3a84c26afa5d774e6b7964b
Autor:
Jennifer R Dungan, Xuejun Qin, Benjamin D Horne, John F Carlquist, Abanish Singh, Melissa Hurdle, Elizabeth Grass, Carol Haynes, Simon G Gregory, Svati H Shah, Elizabeth R Hauser, William E Kraus
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154856 (2016)
Survival bias may unduly impact genetic association with complex diseases; gene-specific survival effects may further complicate such investigations. Coronary artery disease (CAD) is a complex phenotype for which little is understood about gene-speci
Externí odkaz:
https://doaj.org/article/c8a5c97238f14fe0a48da6ba7705c4c1
Autor:
William E Kraus, Deborah M Muoio, Robert Stevens, Damian Craig, James R Bain, Elizabeth Grass, Carol Haynes, Lydia Kwee, Xuejun Qin, Dorothy H Slentz, Deidre Krupp, Michael Muehlbauer, Elizabeth R Hauser, Simon G Gregory, Christopher B Newgard, Svati H Shah
Publikováno v:
PLoS Genetics, Vol 11, Iss 11, p e1005553 (2015)
Levels of certain circulating short-chain dicarboxylacylcarnitine (SCDA), long-chain dicarboxylacylcarnitine (LCDA) and medium chain acylcarnitine (MCA) metabolites are heritable and predict cardiovascular disease (CVD) events. Little is known about
Externí odkaz:
https://doaj.org/article/71d65ad2e8ba483ea543b1b239ab3bdc
Autor:
Carmelo A. Milano, Chetan B. Patel, Christopher L. Holley, Dawn E. Bowles, Lydia Coulter Kwee, Richa Agarwal, Dong-Feng Chen, Adam D. DeVore, Lauren K. Truby, Jacob N. Schroder, Svati H. Shah, Elizabeth Grass
Publikováno v:
J Heart Lung Transplant
PURPOSE: Clinical models to identify patients at high risk of primary graft dysfunction (PGD) after heart transplantation (HT) are limited, and the underlying pathophysiology of this common post-transplant complication remains poorly understood. We s
Autor:
Harvey D. White, Paul W. Armstrong, E. Magnus Ohman, Lenden M. Bowsman, Mark Y. Chan, Svati H. Shah, Simon G. Gregory, Kevin L. Duffin, Joseph V. Haas, Keith A.A. Fox, Megan L. Neely, Elizabeth Grass, Matthew T. Roe, Lydia Coulter Kwee
Publikováno v:
Physiological Genomics
The genomic regulatory networks underlying the pathogenesis of non-ST-segment elevation acute coronary syndrome (NSTE-ACS) are incompletely understood. As intermediate traits, protein biomarkers report on underlying disease severity and prognosis in
Autor:
Robert W. McGarrah, Elizabeth Grass, Lauren K Truby, Christopher L. Holley, Jessica A Regan, Michael R. Bristow, Carmelo A. Milano, Lydia Coulter Kwee, Dawn E. Bowles, Svati H. Shah
Publikováno v:
Circulation. 142
Introduction: There is a complex epidemiologic relationship between type two diabetes mellitus (DM) and heart failure (HF), and it is unclear whether the biochemical basis of HF differs in patients with and without DM. Hypothesis: Proteomic profiling
Autor:
Lydia Coulter Kwee, Kristian C. Becker, Harvey D. White, Megan L. Neely, Joseph A. Jakubowski, Mark Y. Chan, Svati H. Shah, Leonardo de Pinto Carvalho, Elizabeth Grass, Matthew T. Roe, Simon G. Gregory, Keith A.A. Fox, Paul A. Gurbel, E. Magnus Ohman, Richard C. Becker
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Changes in platelet physiology are associated with simultaneous changes in microRNA concentrations, suggesting a role for microRNA in platelet regulation. Here we investigated potential associations between microRNA and platelet reactivity (PR), a ma
Autor:
Mark Y. Chan, Megan L. Neely, Alice Wang, E. Magnus Ohman, Elizabeth Grass, Matthew T. Roe, Simon G. Gregory, Keith A.A. Fox, Paul W. Armstrong, Harvey D. White, Lydia Coulter Kwee, Svati H. Shah
Publikováno v:
Atherosclerosis. 261:19-25
Although circulating microRNA (miRNAs) have emerged as biomarkers predicting mortality in acute coronary syndrome (ACS), more data are needed to understand these mechanisms. Mapping miRNAs to high-risk traits may identify miRNAs involved in pathways