Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Elizabeth Gradelski"'
Publikováno v:
International Journal of Antimicrobial Agents. 20:57-60
Non-fermentative Gram-negative bacteria (Pseudomonas aeruginosa, Burkholderia cepacia, Stenotrophomonas maltophilia and Acinetobacter spp.) are intrinsically less susceptible to many antimicrobial agents. Two-drug combinations have been used to treat
Autor:
Junius M. Clark, Michael J. Pucci, Susan Chaniewski, E Huczko, Cheryl Ferraro, Elizabeth Gradelski, Beatrice Minassian, Y H Tsai, Lucinda Lamb, Ivette Medina, Joan Fung-Tomc, D P Bonner, B Kolek, Thomas Washo
Publikováno v:
Antimicrobial Agents and Chemotherapy. 46:971-976
The recent emergence of methicillin-resistant Staphylococcus aureus (MRSA) with decreased susceptibility to vancomycin has intensified the search for alternative therapies for the treatment of infections caused by this organism. One approach has been
Autor:
Beatrice Minassian, Cheryl Ferraro, Y H Tsai, Junius M. Clark, B Kolek, E Huczko, Susan Chaniewski, Joan Fung-Tomc, Rebecca L. Drain, Elizabeth Gradelski, D P Bonner, Hyekyung Yang
Publikováno v:
Antimicrobial Agents and Chemotherapy. 46:1108-1111
BMS-247243, a novel cephalosporin inhibitory for methicillin-resistant staphylococci, primarily has activity against gram-positive bacteria. The activities of BMS-247243, cefotaxime, and ceftriaxone against streptococci and Streptococcus pneumoniae w
Publikováno v:
Journal of Antimicrobial Chemotherapy. 48:735-738
Publikováno v:
International Journal of Antimicrobial Agents. 18:43-48
The primary bactericidal classes used therapeutically as single agents, are the quinolones and the cell-wall active agents. In this study, their rates of killing were compared. The des-fluoro(6) quinolone BMS-284756 (T-3811ME), fluoroquinolones (trov
Autor:
Joan Fung-Tomc, B Kolek, D P Bonner, R K Flamm, Beatrice Minassian, Elizabeth Gradelski, K Bush
Publikováno v:
Antimicrobial Agents and Chemotherapy. 41:1010-1016
The in vitro activities of a new catechol-containing monobactam, BMS-180680 (SQ 84,100), were compared to those of aztreonam, ceftazidime, imipenem, piperacillin-tazobactam, ciprofloxacin, amikacin, and trimethoprim-sulfamethoxazole. BMS-180680 was o
Autor:
B Kolek, Elizabeth Gradelski, R E Kessler, Michael J. Pucci, D P Bonner, Joan Fung-Tomc, Beatrice Minassian
Publikováno v:
Antimicrobial Agents and Chemotherapy. 39:386-393
The broad antipseudomonal spectrum of the carbapenem BMS-181139 includes clinical strains and laboratory mutants of Pseudomonas aeruginosa that are resistant to imipenem. Unlike other known carbapenems (meropenem, panipenem, biapenem, and BO-2727), w
Autor:
D P Bonner, B Kolek, Marcel Menard, Elizabeth Gradelski, R E Kessler, J Banville, Joan Fung-Tomc, E Huczko
Publikováno v:
Antimicrobial Agents and Chemotherapy. 39:394-399
A number of carbapenem derivatives were examined to determine the structure-activity relationships required for dependence on porin protein D2 for activity against Pseudomonas aeruginosa. As suggested by J. Trias and H. Nikaido (Antimicrob. Agents Ch
Publikováno v:
Journal of Antimicrobial Chemotherapy. 50:140-142
Publikováno v:
Journal of Antimicrobial Chemotherapy. 32:75-80
Step-wise resistance to cefepime, ceftazidime, cefotaxime, and cefpirome were determined for 16 Pseudomonas aeruginosa strains by daily transfer for 7 days to fresh media containing two-fold serial dilution of antibiotic. By the third transfer 4 of 1