Grandisin induces apoptosis in leukemic K562 cells

Autor: Elizabeth Gomes Paulino Menezes, Marize Campos Valadares, Eliana Martins Lima, Alane Pereira Cortez, Alexandre Pereira dos Santos, Higor de Oliveira Ribeiro, Larissa Moreira Cleres, Polyana Lopes Benfica, Massuo J. Kato

Publikováno v: Brazilian Journal of Pharmaceutical Sciences; Vol. 53 No. 1 (2017); e15210
Brazilian Journal of Pharmaceutical Sciences; Vol. 53 Núm. 1 (2017); e15210
Brazilian Journal of Pharmaceutical Sciences; v. 53 n. 1 (2017); e15210
Brazilian Journal of Pharmaceutical Sciences
Universidade de São Paulo (USP)
instacron:USP
Brazilian Journal of Pharmaceutical Sciences, Vol 53, Iss 1 (2017)
Brazilian Journal of Pharmaceutical Sciences, Volume: 53, Issue: 1, Article number: e15210, Published: 20 APR 2017

In this study, the potential antileukemic activity of grandisin, a lignan extracted from Piper solmsianum, was evaluated against the leukemic line K562. The cytotoxicity of grandisin (0.018 to 2.365 µM) was evaluated in K562 and normal peripheral bl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8abff0f73926f509dcfc5297d694e457
https://www.revistas.usp.br/bjps/article/view/131421