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Publikováno v:
BMC Genomics
BMC Genomics, Vol 10, Iss 1, p 202 (2009)
BMC Genomics, Vol 10, Iss 1, p 202 (2009)
Background The wide use of organophosphorus (OP) pesticides makes them an important public health concern. Persistent effects of exposure and the mechanism of neuronal degeneration are continuing issues in OP toxicology. To elucidate early steps in t
Publikováno v:
BMC Genomics
Background The principal toxicity of acute organophosphate (OP) pesticide poisoning is the disruption of neurotransmission through inhibition of acetylcholinesterase (AChE). However, other mechanisms leading to persistent effects and neurodegeneratio