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pro vyhledávání: '"Elizabeth Gachie"'
The inherent, age-dependent loss of retinal ganglion cells is related to the lifespan of the species
Autor:
Elizabeth Gachie, Arthur H. Neufeld
Publikováno v:
Neurobiology of Aging. 24:167-172
Retinal ganglion cells are neurons that transmit visual information from the retina to the brain. With age, there is an inherent loss of retinal ganglion cells that we have quantitated by retrograde labeling of these neurons. In adult mice, the loss
Autor:
Shin ichiro Kawai, Sucharita Das, Arthur H. Neufeld, Elizabeth Gachie, Smita C. Vora, Jane R Connor, Pamela T. Manning
Publikováno v:
Experimental Eye Research. 75:521-528
Following experimental, transient, retinal ischemia in the rat, there is loss of retinal neurons, which occurs over several weeks. Retinal ganglion cells (RGCs) are particularly susceptible and there is early, massive degeneration of these neurons af
Autor:
Shin-ichiro Kawai, Jane R. Connor, Arthur H. Neufeld, Pamela T. Manning, Smita C. Vora, Elizabeth Gachie, Sucharita Das
Publikováno v:
Journal of Glaucoma. 11:221-225
To test the hypothesis that nitric oxide, synthesized by inducible nitric oxide synthase, causes degeneration of retinal ganglion cells in an animal model of glaucoma.Rats with unilateral, chronic, moderately elevated intraocular pressure were treate
Autor:
Elizabeth Gachie, Arthur H. Neufeld, Smita C. Vora, Shin-ichiro Kawai, Bernard Becker, Sucharita Das
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 15(7)
SPECIFIC AIMSWe have used a rat model of ischemia/reperfusion injury of the retina to study various risk factors that are relevant to neural injury in the human central nervous system (CNS). We have determined whether age, diet, diabetes, the presenc