Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Elizabeth F. Marshall"'
Publikováno v:
Journal of Psychopharmacology. 16:73-78
Serotonergic function is reduced in dementia of Alzheimer type (DAT) and abnormalities in the hypothalamic-pituitary-adrenal (HPA) axis are also common. There is considerable interaction between the two systems. Effects of lowering brain serotonin on
Autor:
Elizabeth F. Marshall, J.A. Court, Evelyn Jaros, David J. Burn, N Thomas, Elaine K. Perry, S. Lloyd, Mary Johnson, Ian G. McKeith, M.A. Piggott, Robert H. Perry, Clive Ballard
Publikováno v:
Brain. 122:1449-1468
Dementia with Lewy bodies (DLB) is a neuropsychiatric disease associated with extrapyramidal features which differ from those of Parkinson's disease, including reduced effectiveness of L-dopa and severe sensitivity reactions to neuroleptic drugs. Dis
Autor:
Elizabeth F. Marshall, Elaine K. Perry, Robert H. Perry, Margaret A. Piggott, Evelyn Jaros, Peter L. Thompson, David J. Burn
Publikováno v:
Acta Neurologica Scandinavica. 95:287-292
Neurochemical analyses of post-mortem brain from cases of corticobasal degeneration are extremely rare although nearly 100 cases have been reported in the literature. We detail findings of neurotransmitter derangement in the basal ganglia of a case o
Publikováno v:
Journal of the Neurological Sciences. 139:83-90
Serotonin 5-HT is a potent modulator of motor neuron excitability in the spinal cord. Serotonergic neurotransmission, because of its effects on glutamatergic excitation, may be relevant to the pathogenesis and therapy of motor neuron disease (MND). T
Publikováno v:
Acta Psychiatrica Scandinavica. 90:316-323
Clinical, electroencephalographic and biochemical variables were measured in 40 patients who attempted suicide and 27 age-matched controls. Patients had significantly higher scores for depression, hopelessness, neuroticism and psychoticism and lower
Autor:
Robert H. Perry, Elaine K. Perry, John H. Xuereb, Elizabeth F. Marshall, J.M. Candy, James R. Bonham
Publikováno v:
Brain. 114:1363-1379
Serial sections through the thalamus from the fixed right cerebral hemispheres of 15 cases (5 Parkinson's disease, 5 Alzheimer's disease (AD) and 5 controls) were used to obtain quantitative estimates of neuronal loss, neurofibrillary tangle formatio
Autor:
Robert H. Perry, James R. Bonham, J.M. Candy, John H. Xuereb, Elaine K. Perry, Elizabeth F. Marshall
Publikováno v:
Neuropathology and Applied Neurobiology. 16:477-488
The overactivity of glutamatergic neurons may underlie some neurodegenerative disorders, including Alzheimer's disease (AD). We explored the relationship between glutamatergic transmission and neurofibrillary tangle formation by measuring [3H]-D-aspa
Autor:
Elizabeth F. Marshall, John H. Xuereb, J.M. Candy, James R. Bonham, Robert H. Perry, Elaine K. Perry
Publikováno v:
Journal of the Neurological Sciences. 99:185-197
Loss of cholinergic cells in the basal forebrain is associated with commensurate reductions in cortical acetylcholine-related enzyme activities in both Alzheimer's disease (AD) and Parkinson's disease (PD). Nerve cell loss from the cholinergic pontin
Autor:
Robert H. Perry, Elizabeth F. Marshall, N Thomas, J.A. Court, Durval C. Costa, Elaine K. Perry, M.A. Piggott, S. Lloyd, Evelyn Jaros
Publikováno v:
Neuroscience. 90(2)
The human striatum, which receives dopaminergic innervation from the substantia nigra and ventral tegmental area (cell groups A8, A9 and A10), has structural and functional subdivisions both rostrocaudally and dorsoventrally. These relate to motor an
Autor:
Ian G. McKeith, S. Lloyd, Elaine K. Perry, Peter Thompson, Andrew G. Brown, Jennifer A. Court, Robert H. Perry, Heather L. Melrose, M.A. Piggott, Elizabeth F. Marshall, Mary Johnson, Andrew Fairbairn
Publikováno v:
Biological psychiatry. 44(8)
Background: In dementia with Lewy bodies (DLB) mild extrapyramidal symptoms are associated with moderate reductions in substantia nigra neuron density and concentration of striatal dopamine. Many DLB patients treated with typical neuroleptics suffer