Cerebral Erythropoietin Prevents Sex-Dependent Disruption of Respiratory Control Induced by Early Life Stress

Autor: Elizabeth Elliot-Portal, Christian Arias-Reyes, Sofien Laouafa, Rose Tam, Richard Kinkead, Jorge Soliz

Publikováno v: Frontiers in Physiology, Vol 12 (2021)

Injuries that occur early in life are often at the root of adult illness. Neonatal maternal separation (NMS) is a form of early life stress that has persistent and sex-specific effects on the development of neural networks, including those that regul

Externí odkaz: https://doaj.org/article/b5dff72fc6554567b2314de877a6c194

Developmental expression patterns of erythropoietin and its receptor in mouse brainstem respiratory regions

Autor: Christian Arias-Reyes, Elizabeth Elliot-Portal, Edith M. Schneider Gasser, Jorge Soliz, Omolara O. Ogunshola, Karen Losantos-Ramos, Kasifa Khalid

Publikováno v: Respiratory physiologyneurobiology. 267

Erythropoietin (EPO) is a hypoxia-inducible hormone, classically known to enhance red blood cell production upon binding its receptor (EPOR) present on the surface of the erythroid progenitor cells. EPO and its receptor are also expressed in the cent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa657235d6eaec1eff4bf8aa1f437017
https://pubmed.ncbi.nlm.nih.gov/31154093

Brain-derived erythropoietin protects from intermittent hypoxia-induced cardiorespiratory dysfunction and oxidative stress in mice

Autor: Vincent Joseph, Christian Arias-Reyes, Tara Adele Janes, Jorge Soliz, Elizabeth Elliot-Portal, Sofien Laouafa

Publikováno v: Sleep. 41(7)

Study objectives Based on the fact that erythropoietin (Epo) administration in rodents protects against spatial learning and cognitive deficits induced by chronic intermittent hypoxia (CIH)-mediated oxidative damage, here we tested the hypothesis tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fe2edc1159748b085e1253ea795361f
https://pubmed.ncbi.nlm.nih.gov/29697839

Pharmacological, but not genetic, alteration of neural Epo modifies the CO2/H+ central chemosensitivity in postnatal mice

Autor: Jorge Soliz, Anne-Sophie Perrin-Terrin, Elizabeth Elliot-Portal, Laurence Bodineau, Sofien Laouafa, Nicolas Voituron, Florine Jeton, Rose Tam

Publikováno v: Respiratory Physiology and Neurobiology
Respiratory Physiology and Neurobiology, Elsevier, 2017, 242, pp.73-79. ⟨10.1016/j.resp.2017.04.003⟩
Respiratory Physiology & Neurobiology
Respiratory Physiology & Neurobiology, 2017, 242, pp.73-79. ⟨10.1016/j.resp.2017.04.003⟩

International audience; Cerebral erythropoietin (Epo) plays a crucial role for respiratory control in newborn rodents. We showed previously that soluble Epo receptor (sEpoR: an Epo antagonist) reduces basal ventilation and hypoxic hyperventilation at

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9018cf3feb4afedb3f5a8bbe095cf38c
https://hal-sde.archives-ouvertes.fr/hal-01529039