Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Elizabeth E. Zumbrun"'
Autor:
Elizabeth E. Zumbrun, Samantha E. Zak, Eric D. Lee, Philip A. Bowling, Sara I. Ruiz, Xiankun Zeng, Jeffrey W. Koehler, Korey L. Delp, Russel R. Bakken, Shannon S. Hentschel, Holly A. Bloomfield, Keersten M. Ricks, Tamara L. Clements, April M. Babka, John M. Dye, Andrew S. Herbert
Publikováno v:
Viruses, Vol 15, Iss 12, p 2341 (2023)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the worldwide COVID-19 pandemic. Animal models are extremely helpful for testing vaccines and therapeutics and for dissecting the viral and host factors that contr
Externí odkaz:
https://doaj.org/article/bd56c47970434e62b1faeb69e1895bd8
Autor:
Elizabeth E. Zumbrun, Carly B. Garvey, Jay B. Wells, Ginger C. Lynn, Sean Van Tongeren, Jesse T. Steffens, Kelly S. Wetzel, Laura M. Gomba, Kristan A. O’Brien, Franco D. Rossi, Xiankun Zeng, Eric D. Lee, Jo Lynne W. Raymond, Diana A. Hoffman, Alexandra N. Jay, Elizabeth S. Brown, Paul A. Kallgren, Sarah L. Norris, Jean Cantey-Kiser, Humza Kudiya, Chris Arthur, Christiana Blair, Darius Babusis, Victor C. Chu, Bali Singh, Roy Bannister, Danielle P. Porter, Tomas Cihlar, John M. Dye
Publikováno v:
Viruses, Vol 15, Iss 12, p 2335 (2023)
Marburg virus (MARV) causes severe disease and high mortality in humans. The objective of this study was to characterize disease manifestations and pathogenesis in cynomolgus macaques exposed to MARV. The results of this natural history study may be
Externí odkaz:
https://doaj.org/article/888ce560fbcf4156b170e652f06b91dc
Autor:
Sabah Kadhim, Narendra P. Singh, Elizabeth E. Zumbrun, Taixing Cui, Saurabh Chatterjee, Lorne Hofseth, Abduladheem Abood, Prakash Nagarkatti, Mitzi Nagarkatti
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Resveratrol (RES) is a polyphenolic compound found abundantly in plant products including red grapes, peanuts, and mulberries. Because of potent anti-inflammatory properties of RES, we investigated whether RES can protect from Staphylococcal enteroto
Externí odkaz:
https://doaj.org/article/5877de22a2f244ba90b5a43dc7e1eec3
Autor:
Christopher P. Stefan, Catherine E. Arnold, Charles J. Shoemaker, Elizabeth E. Zumbrun, Louis A. Altamura, Christina E. Douglas, Cheryl L. Taylor-Howell, Amanda S. Graham, Korey L. Delp, Candace D. Blancett, Keersten M. Ricks, Scott P. Olschner, Joshua D. Shamblin, Suzanne E. Wollen, Justine M. Zelko, Holly A. Bloomfield, Thomas R. Sprague, Heather L. Esham, Timothy D. Minogue
Publikováno v:
Microorganisms, Vol 9, Iss 3, p 665 (2021)
Ebola virus is a continuing threat to human populations, causing a virulent hemorrhagic fever disease characterized by dysregulation of both the innate and adaptive host immune responses. Severe cases are distinguished by an early, elevated pro-infla
Externí odkaz:
https://doaj.org/article/c21b1886ea734d4698af53bc4d5660ab
Autor:
Gene G. Olinger, Ana Kuehne, Jennifer L. Audet, Kendra J. Alfson, Anthony Griffiths, Holly A. Bloomfield, Elizabeth E. Zumbrun, Ashley E. Keeney, Julia E. Biggins, Amy C. Shurtleff, Sina Bavari
Publikováno v:
Viruses, Vol 4, Iss 12, Pp 3511-3530 (2012)
The filovirus plaque assay serves as the assay of choice to measure infectious virus in a cell culture, blood, or homogenized tissue sample. It has been in use for more than 30 years and is the generally accepted assay used to titrate virus in sample
Externí odkaz:
https://doaj.org/article/95754ee8eadb4ba3a0d99635d2cb8307
Autor:
Malak Kotb, Paige E. Harrison, Donald K. Nichols, Taylor B. Chance, Holly A. Bloomfield, Nourtan F. Abdeltawab, Elizabeth E. Zumbrun, Aysegul Nalca
Publikováno v:
Viruses, Vol 4, Iss 12, Pp 3468-3493 (2012)
Countering aerosolized filovirus infection is a major priority of biodefense research. Aerosol models of filovirus infection have been developed in knock-out mice, guinea pigs and non-human primates; however, filovirus infection of immunocompetent mi
Externí odkaz:
https://doaj.org/article/0becb158ed7949429a0c7a6afbc8173d
Autor:
Donald K. Nichols, Roger D. Williams, Reese J. Baker, Nicole L. Garza, Nicholas R. Bramel, Paul A. Dabisch, Ty C. Hunter, John M. Dye, Holly A. Bloomfield, Elizabeth E. Zumbrun, Aysegul Nalca
Publikováno v:
Viruses, Vol 4, Iss 10, Pp 2115-2136 (2012)
Filoviruses are members of the genera Ebolavirus, Marburgvirus, and “Cuevavirus”. Because they cause human disease with high lethality and could potentially be used as a bioweapon, these viruses are classified as CDC Category A Bioterrorism Agent
Externí odkaz:
https://doaj.org/article/1b2481a632b54cf7ad078b852811535a
Autor:
Elizabeth E. Zumbrun, Chengzi I. Kaku, Lukas Dillinger, Samantha E. Zak, Ana I. Kuehne, Russel R. Bakken, Jeffrey W. Koehler, Korey L. Delp, Christopher P. Stefan, Raina Kumar, Jeffrey R. Kugelman, Alicia M. Moreau, Xiankun Zeng, John M. Dye, Andrew S. Herbert, Kristin Narayan, Laura M. Walker
Publikováno v:
Antimicrobial Agents and Chemotherapy. 67
Adintrevimab is a human immunoglobulin G1 monoclonal antibody engineered to have broad neutralization against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants and other SARS-like coronaviruses with pandemic potential. In both Syr
Autor:
Shannon Martin, Mariano Sanchez-Lockhart, Amy C. Shurtleff, Jeffrey R. Kugelman, Elizabeth E. Zumbrun, David L. Saunders, Travis K. Warren, Brett P. Eaton, Gustavo Palacios, Xiankun Zeng, Jens H. Kuhn, Allen J. Duplantier, Christopher L. Cooper, Farooq Nasar, Rajini Mudhasani, Rekha G. Panchal, Margaret L. Pitt, J Matthew Meinig, Ian Crozier, Chih-Yuan Chiang, Christopher D. Kane, Sandra L. Bixler, Sheli R. Radoshitzky, Karen A. Martins, Patrick L. Iversen, Melek M. E. Sunay
Publikováno v:
The Lancet. Infectious Diseases
Summary The PALM trial in the Democratic Republic of the Congo identified a statistically significant survival benefit for two monoclonal antibody-based therapeutics in the treatment of acute Ebola virus disease; however, substantial gaps remain in i
Autor:
Scott P Olschner, Christopher P. Stefan, Christina E. Douglas, Candace D. Blancett, Keersten M. Ricks, Catherine E. Arnold, Cheryl L. Taylor-Howell, Timothy D. Minogue, Korey L Delp, Elizabeth E. Zumbrun, Holly A. Bloomfield, Thomas R. Sprague, Suzanne E. Wollen, Justine M. Zelko, Joshua D. Shamblin, Louis A. Altamura, Amanda S. Graham, Charles J. Shoemaker, Heather L. Esham
Publikováno v:
Microorganisms
Volume 9
Issue 3
Microorganisms, Vol 9, Iss 665, p 665 (2021)
Volume 9
Issue 3
Microorganisms, Vol 9, Iss 665, p 665 (2021)
Ebola virus is a continuing threat to human populations, causing a virulent hemorrhagic fever disease characterized by dysregulation of both the innate and adaptive host immune responses. Severe cases are distinguished by an early, elevated pro-infla