Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Elizabeth E. Doolin"'
Autor:
Annabell F. Leske, Julie Martyn, Tina C. Lavranos, David Espinoza, Dirkje W. Sommeijer, Jose Iglesias, Philip Beale, Elizabeth E. Doolin, Jeremy Simpson, Danny Rischin, Jeff C. Goh, Gabriel Kremmidiotis, Emma C. Rossi, Kristina Lindemann, Anneso S. Veillard, Martin R. Stockler, Michelle Margaret Vaughan, Meaghan Tenney
Publikováno v:
Cancer chemotherapy and pharmacology, 83(1), 97-105. Springer Verlag
Purpose: The primary objective of this study was to determine the recommended dose of the vascular disrupting agent, BNC105P, in combination with gemcitabine and carboplatin in patients with ovarian cancer in first or second relapse with a minimum 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1505eabd827e65c42487a3157a87ae2b
https://pure.amc.nl/en/publications/phase-i-study-of-bnc105p-carboplatin-and-gemcitabine-in-partially-platinumsensitive-ovarian-cancer-patients-in-first-or-second-relapse-anzgog1103(bec4efc5-2158-432c-b127-5dc2abc25aa3).html
https://pure.amc.nl/en/publications/phase-i-study-of-bnc105p-carboplatin-and-gemcitabine-in-partially-platinumsensitive-ovarian-cancer-patients-in-first-or-second-relapse-anzgog1103(bec4efc5-2158-432c-b127-5dc2abc25aa3).html
Autor:
Richard C. Lauer, Ravindran Kanesvaran, Gabriel Kremmidiotis, Harry A. Drabkin, Thomas E. Hutson, Jose Iglesias, Timothy Breen, Alexander Starodub, Christopher Sweeney, Stephen Lane Richey, Brian A. Costello, Shailender Bhatia, David C. Bibby, Jeremy Simpson, Annabell F. Leske, Sumanta K. Pal, Ralph J. Hauke, Elizabeth E. Doolin, Arun Azad, Guru Sonpavde, Noah M. Hahn, John Sarantopoulos
Publikováno v:
Clinical Cancer Research. 21:3420-3427
Purpose: BNC105P inhibits tubulin polymerization, and preclinical studies suggest possible synergy with everolimus. In this phase I/II study, efficacy and safety of the combination were explored in patients with metastatic renal cell carcinoma (mRCC)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0b0b215f9b26cd05e303e8eb87359e6
https://doi.org/10.1158/1078-0432.ccr-14-3370
https://doi.org/10.1158/1078-0432.ccr-14-3370
Autor:
Elizabeth E Doolin, A.R McCarthy, Murray W. Woolford, Bryce M. Buddle, D. Neil Wedlock, S. Jane Lacy-Hulbert
Publikováno v:
Journal of Dairy Research. 71:154-161
We examined the effects of administering recombinant bovine cytokines to non-lactating dairy cows and measured mammary gland leucocytes and the involution process. After the final milking, groups of cows were given an intramammary infusion of cytokin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86b4728de9e82185484084333abd0f4
https://doi.org/10.1017/s0022029904000111
https://doi.org/10.1017/s0022029904000111
Publikováno v:
Immunology & Cell Biology. 80:358-363
Vaccination strategies for the brushtail possum, which rely upon stimulation of mucosal immunity, are being developed for biocontrol purposes. As little is known about how to stimulate possum immune responses via a mucosal site, groups of possums wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b94891dfc734dae5559a620979e784d2
https://doi.org/10.1046/j.1440-1711.2002.01096.x
https://doi.org/10.1046/j.1440-1711.2002.01096.x
Autor:
Natalie A. Parlane, Bryce M. Buddle, S. J. Lacy-Hulbert, Murray W. Woolford, Elizabeth E Doolin, D.N. Wedlock
Publikováno v:
Journal of Dairy Research. 67:189-197
The physiological effects of intramammary infusions of recombinant bovine cytokines in six lactating dairy cows on the quality and yield of milk and the bactericidal activity of milk neutrophils were investigated. Recombinant bovine interleukin-2 (rb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f63794300cba514b2d9d2e8d6dcf2ac
https://doi.org/10.1017/s0022029900004131
https://doi.org/10.1017/s0022029900004131
Publikováno v:
Cancer Research. 75:1551-1551
BNC105 is a tubulin depolymerisation agent. Its activity includes effects on both cancer cells and on solid tumor microvasculature. BNC105 shows evidence of strong anti-cancer efficacy in vitro and in animal models. In solid tumors its efficacy is dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f517551640e52fbf3476c39aadcada21
https://doi.org/10.1158/1538-7445.am2015-1551
https://doi.org/10.1158/1538-7445.am2015-1551
Autor:
Annabell F. Leske, N. Hahn, Richard C. Lauer, Ravindran Kanesvaran, Thomas E. Hutson, Arun Azad, David C. Bibby, Stephen Lane Richey, Gabriel Kremmidiotis, Jose Iglesias, Timothy Breen, Brian A. Costello, Shailender Bhatia, Jeremy Simpson, Guru Sonpavde, Harry A. Drabkin, Sumanta K. Pal, John Sarantopoulos, Elizabeth E. Doolin, Christopher Sweeney
Publikováno v:
European Journal of Cancer. 51:e26
Background In patients with metastatic renal cell carcinoma (mRCC), everolimus represents a standard of care option for patients who have had prior vascular endothelial growth factor (VEGF)-directed therapy. BNC105P is an inhibitor of tubulin polymer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64dff8c0fd29c13116e37836a2fa5560
https://doi.org/10.1016/j.ejca.2015.06.078
https://doi.org/10.1016/j.ejca.2015.06.078
Autor:
Jose Iglesias, Timothy Breen, Arun Azad, Sumanta K. Pal, Brian A. Costello, Jeremy Simpson, Thomas E. Hutson, David C. Bibby, Stephen Lane Richey, John Sarantopoulos, Annabell F. Leske, Christopher Sweeney, Noah M. Hahn, Sumeet Bhatia, Guru Sonpavde, Elizabeth E. Doolin, Harry A. Drabkin, Richard C. Lauer, Ravindran Kanesvaran, Gabriel Kremmidiotis
Publikováno v:
Journal of Clinical Oncology. 33:475-475
475 Background: The vascular disrupting agent (VDA) BNC105P shows synergy with everolimus in preclinical models. The DisrupTOR-1 trial included a phase I component exploring this combination and a randomized phase II component comparing everolimus wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d44b66e7b7b6c17b4aa434eba1937b5e
https://doi.org/10.1200/jco.2015.33.7_suppl.475
https://doi.org/10.1200/jco.2015.33.7_suppl.475
Purification of secretory immunoglobulin A from milk of the brushtail possum (Trichosurus vulpecula)
Publikováno v:
New Zealand veterinary journal. 49(5)
To identify and purify secretory immunoglobulin A (sIgA), a key effecter molecule in mucosal immune responses, from milk of the brushtail possum (Trichosurus vulpecula).Milk samples were collected from female possums with pouch young, and clarified b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8991fd9304301c2010eb7e2b9b89e2d
https://pubmed.ncbi.nlm.nih.gov/16032190
https://pubmed.ncbi.nlm.nih.gov/16032190
Autor:
Arun Azad, Jose Iglesias, Timothy Breen, Brian A. Costello, Noah M. Hahn, Elizabeth E. Doolin, Guru Sonpavde, Sumanta K. Pal, J. Sarantopolous, Christopher Sweeney, Thomas E. Hutson, Stephen Lane Richey, Richard C. Lauer, Ravindran Kanesvaran, J. Simpson, Gabriel Kremmidiotis, David C. Bibby, Harry A. Drabkin, Shailender Bhatia
Publikováno v:
Annals of Oncology. 25:iv283
1 City of Hope Medical Center, Duarte, CA, 2 BC Cancer Agency, Vancouver, BC, 3 Univ. of Washington, Seattle, WA, 4 Medical College of South Carolina, Charleston, SC, 5 Mayo Clinic, Rochester, MN, 6 Univ.of Texas Health Science Center, San Antonio, T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0e0fc4af6346830e4148220ceaa33c7
https://doi.org/10.1093/annonc/mdu337.8
https://doi.org/10.1093/annonc/mdu337.8