Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Elizabeth E Torr"'
Human induced pluripotent stem cell-derived planar neural organoids assembled on synthetic hydrogels
Autor:
Joydeb Majumder, Elizabeth E Torr, Elizabeth A Aisenbrey, Connie S Lebakken, Peter F Favreau, William D Richards, Yanhong Yin, Qiang Chang, William L Murphy
Publikováno v:
Journal of Tissue Engineering, Vol 15 (2024)
The tailorable properties of synthetic polyethylene glycol (PEG) hydrogels make them an attractive substrate for human organoid assembly. Here, we formed human neural organoids from iPSC-derived progenitor cells in two distinct formats: (i) cells see
Externí odkaz:
https://doaj.org/article/86c87a2ea4184847a73652280ca741fb
Autor:
Stephane Esnault, Elizabeth E Torr, Ksenija Bernau, Mats W Johansson, Elizabeth A Kelly, Nathan Sandbo, Nizar N Jarjour
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170207 (2017)
Semaphorin-7A is a glycosylphosphatidylinositol-anchored protein, initially characterized as an axon guidance protein. Semaphorin-7A also contributes to immune cell regulation and may be an essential pro-fibrotic factor when expressed by non-fibrobla
Externí odkaz:
https://doaj.org/article/fdde17c81f8c4e489193f342ff2899a2
Autor:
Sungjin Park, Smit A. Patel, Elizabeth E. Torr, Ashley-Grace N. Dureke, Alina M. McIntyre, Ahna R. Skop
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102562- (2023)
Summary: Traditionally, midbody remnants (MBRs) are isolated from cell culture medium using ultracentrifugation, which is expensive and time consuming. Here, we present a protocol for isolating MBRs or large extracellular vesicles (EVs) from mammalia
Externí odkaz:
https://doaj.org/article/74dd531aa6e14b6a808b7bc17a27992b
Autor:
Elizabeth E. Torr, William L. Murphy, Elizabeth A. Aisenbrey, Cheryl M. Soref, Hunter J. Johnson, William T. Daly
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100261-(2021)
STAR Protocols
STAR Protocols
Summary Pericytes play a critical role in promoting, regulating, and maintaining numerous vascular functions. Their dysfunction is a major contributor to the progression of vascular and neurodegenerative diseases, making them an ideal candidate for l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::317741bfa2f8c0e99b290a166c104963
http://www.sciencedirect.com/science/article/pii/S2666166720302483
http://www.sciencedirect.com/science/article/pii/S2666166720302483
Autor:
Suehelay Acevedo-Acevedo, Brian P. Johnson, David J. Beebe, Jessica Antosiewicz-Bourget, Elizabeth E. Torr, William L. Murphy, Victoria Harms, James A. Thomson, Peyton Uhl, Hunter J. Johnson, Jonathan C. Evans, Cheryl M. Soref, William T. Daly, Sean P. Palecek, Daniel Mamott, Gaurav Kaushik, Kartik Gupta
Publikováno v:
Adv Healthc Mater
There is a vital need to develop in vitro models of the developing human brain to recapitulate the biological effects that toxic compounds have on the brain. To model perineural vascular plexus (PNVP) in vitro, which is a key stage in embryonic devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e009513195dde42b0b3ad3c911856af6
https://europepmc.org/articles/PMC8016604/
https://europepmc.org/articles/PMC8016604/
Autor:
Nathan Sandbo, Keith T. Ferguson, Ksenija Bernau, David Sherris, Elizabeth E. Torr, Jonathan P Leet
Publikováno v:
Journal of Cellular Biochemistry. 118:2241-2249
Idiopathic pulmonary fibrosis is a progressive and deadly disorder with very few therapeutic options. Palomid 529 (8-(1-hydroxyethyl)-2-methoxy-3-(4-methoxybenzyloxy)-benzo[c]chromen-6-one; P529) is a novel dual inhibitor of mechanistic target of rap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4179680b89c1cce4a4b65bfcd818f397
https://doi.org/10.1002/jcb.25878
https://doi.org/10.1002/jcb.25878
Autor:
Elizabeth E. Torr, William L. Murphy, Daniel A. Gil, Melissa C. Skala, Linda G. Griffith, Peyton Uhl, Gaurav Kaushik, William T. Daly, James A. Thomson, Collin Edington, Cheryl M. Soref, Gianluca Fontana, Michael P. Schwartz, Elizabeth S. Berge, Jessica Antosiewicz-Bourget
Publikováno v:
PMC
Vascularization is an important strategy to overcome diffusion limits and enable the formation of complex, physiologically relevant engineered tissues and organoids. Self-assembly is a technique to generate in vitro vascular networks, but engineering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e49a894ed4107dfd56a34e5c180bf82
https://pubmed.ncbi.nlm.nih.gov/30565891
https://pubmed.ncbi.nlm.nih.gov/30565891
Autor:
William T. Daly, Michael P. Schwartz, Daniel A. Gil, Elizabeth S. Berge, Jessica Antosiewicz-Bourget, Collin Edington, Melissa C. Skala, Cheryl M. Soref, Gianluca Fontana, Gaurav Kaushik, Peyton Uhl, Elizabeth E. Torr, William L. Murphy, James A. Thomson, Linda G. Griffith
Publikováno v:
Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVI.
Engineered tissues offer great promise as engrafted therapies and in vitro models, but these tissues require a vascular network to retain viability at large scales. Significant efforts are focused on optimizing these in vitro vascular constructs, yet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc88aa20736c5b29029e912ea8bc6fa1
https://doi.org/10.1117/12.2290562
https://doi.org/10.1117/12.2290562
Autor:
Ksenija Bernau, Nizar N. Jarjour, Stephane Esnault, Elizabeth E. Torr, Nathan Sandbo, Yury A. Bochkov
Publikováno v:
Respiratory Research
Respiratory Research, Vol 18, Iss 1, Pp 1-16 (2017)
Respiratory Research, Vol 18, Iss 1, Pp 1-16 (2017)
Background The association of eosinophils with inflammation and tissue remodeling is at least partially due to their release of toxic granule proteins and other mediators, including cytokines. Tissue remodeling and consequent functional defects are a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::688baab86df30bab8dac91f2a183ebd8
http://europepmc.org/articles/PMC5681771
http://europepmc.org/articles/PMC5681771
Autor:
Michael D. Evans, Nathan Sandbo, Ksenija Bernau, Jason K. Aoki, Caitlyn Ngam, Elizabeth E. Torr
Myofibroblasts, the primary effector cells that mediate matrix remodeling during pulmonary fibrosis, rapidly assemble an extracellular fibronectin matrix. Tensin (TNS) 1 is a key component of specialized cellular adhesions (fibrillar adhesions) that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17383a6e64ecde8a00e2361270a7ae80
https://europepmc.org/articles/PMC5449508/
https://europepmc.org/articles/PMC5449508/