Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Elizabeth E Pierson"'
Autor:
Chao Chen, Joseph Che-Yen Wang, Elizabeth E Pierson, David Z Keifer, Mildred Delaleau, Lara Gallucci, Christian Cazenave, Michael Kann, Martin F Jarrold, Adam Zlotnick
Publikováno v:
PLoS Pathogens, Vol 12, Iss 8, p e1005802 (2016)
Hepatitis B virus (HBV) capsids are found in many forms: immature single-stranded RNA-filled cores, single-stranded DNA-filled replication intermediates, mature cores with relaxed circular double-stranded DNA, and empty capsids. A capsid, the protein
Externí odkaz:
https://doaj.org/article/6da743e70a024966bb67ca76e98bcc91
Autor:
Alena Bensussan, Roy Helmy, Bindesh Shrestha, Hernando J. Olivos, Vivek Shah, Elizabeth E. Pierson, William P. Forrest, Ryan S. Teller, Anthony J. Midey, Seth P. Forster
Publikováno v:
Pharmaceutical Research. 37
Desorption electrospray ionization mass spectrometry imaging (DESI-MSI) coupled with gas-phase ion mobility spectrometry was used to characterize the drug distribution in polymeric implants before and after exposure to accelerated in vitro release (I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3987547d67cbf25a8f0ff3451cf677a
https://doi.org/10.1007/s11095-020-02823-x
https://doi.org/10.1007/s11095-020-02823-x
Autor:
Elizabeth E. Pierson, Nicholas E. Brunk, Joseph Che Yen Wang, Stephen C. Jacobson, Adam Zlotnick, Panagiotis Kondylis, Martin F. Jarrold, Daniel G. Haywood, David Z. Keifer, Lye Siang Lee
Publikováno v:
Protein Science. 26:2170-2180
Hepatitis B virus (HBV) core protein is a model system for studying assembly and disassembly of icosahedral structures. Controlling disassembly will allow re-engineering the 120 subunit HBV capsid, making it a molecular breadboard. We examined remova
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b5acc1dff913f80f1cd9325964a963
https://doi.org/10.1002/pro.3265
https://doi.org/10.1002/pro.3265
Publikováno v:
The Analyst. 142:1654-1671
Charge detection mass spectrometry (CDMS) is a single molecule method where the mass of each ion is directly determined from individual measurements of its mass-to-charge ratio and charge. CDMS is particularly valuable for the analysis of high mass a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b516d6ba326cb7b2d37f89ea79028f4
https://doi.org/10.1039/c7an00277g
https://doi.org/10.1039/c7an00277g
Autor:
Joseph Che Yen Wang, Martin F. Jarrold, Elizabeth E. Pierson, David Z. Keifer, Adam Zlotnick, Alexander A. Kukreja
Publikováno v:
Journal of Molecular Biology. 428:292-300
Woodchuck hepatitis virus (WHV) is prone to aberrant assembly in vitro and can form a broad distribution of oversized particles. Characterizing aberrant assembly products is challenging because they are both large and heterogeneous. In this work, cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6330b39c6aeabc977b9f6bc6a9e5a615
https://doi.org/10.1016/j.jmb.2015.06.019
https://doi.org/10.1016/j.jmb.2015.06.019
Autor:
Zhenning Tan, Bogdan Dragnea, David Z. Keifer, Lisa Selzer, Martin F. Jarrold, Joseph Che Yen Wang, Alexander A. Kukreja, Adam Zlotnick, Elizabeth E. Pierson
Publikováno v:
Journal of Virology. 88:14105-14115
Woodchuck hepatitis virus (WHV), a close relative of human hepatitis B virus (HBV), has been a key model for disease progression and clinical studies. Sequences of the assembly domain of WHV and HBV core proteins (wCp149 and hCp149, respectively) hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a32d58fed89549051a35620c7769f2a7
https://doi.org/10.1128/jvi.01840-14
https://doi.org/10.1128/jvi.01840-14
Autor:
Nicholas A. Lyktey, Corinne A. Lutomski, Adam Zlotnick, Zhongchao Zhao, Elizabeth E. Pierson, Martin F. Jarrold
Publikováno v:
Journal of the American Chemical Society. 139(46)
Understanding capsid assembly is important because of its role in virus lifecycles and in applications to drug discovery and nanomaterial development. Many virus capsids are icosahedral, and assembly is thought to occur by the sequential addition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d6a44b118c032782cddc20321037258
https://pubmed.ncbi.nlm.nih.gov/29125756
https://pubmed.ncbi.nlm.nih.gov/29125756
Autor:
Joseph Che Yen Wang, Martin F. Jarrold, Lye Siang Lee, Elizabeth E. Pierson, Nathan C. Contino, Adam Zlotnick, Lisa Selzer, David Z. Keifer
Publikováno v:
Journal of the American Chemical Society
The assembly of hundreds of identical proteins into an icosahedral virus capsid is a remarkable feat of molecular engineering. How this occurs is poorly understood. Key intermediates have been anticipated at the end of the assembly reaction, but it h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0feaa80ff16974cf114bf3b604661cac
https://doi.org/10.1021/ja411460w
https://doi.org/10.1021/ja411460w
Autor:
David Z. Keifer, Peter E. Prevelige, Gregory J. Bedwell, Martin F. Jarrold, Joanna A. Hogan, Elizabeth E. Pierson
Publikováno v:
Rapid Communications in Mass Spectrometry. 28:483-488
RATIONALE Charge state resolution is required to determine the masses of ions in electrospray mass spectrometry, a feat which becomes increasingly difficult as the mass increases. Charge detection mass spectrometry (CDMS) circumvents this limitation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79069903f5f7847ce40550d44413c3da
https://doi.org/10.1002/rcm.6809
https://doi.org/10.1002/rcm.6809
Publikováno v:
International Journal of Mass Spectrometry. 337:50-56
Pyruvate kinase multimers have been investigated by charge detection mass spectrometry (CDMS). In CDMS, the m / z and z are simultaneously measured for each ion, so the mass is determined directly. The measurements were made using a modified cone tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b66ca4684d11eceb49e5b79f7eff47ca
https://doi.org/10.1016/j.ijms.2013.01.002
https://doi.org/10.1016/j.ijms.2013.01.002