Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Elizabeth E Martelli"'
Autor:
Manveen K. Gupta, Anita Sahu, Yu Sun, Maradumane L. Mohan, Avinash Kumar, Ajaykumar Zalavadia, Xi Wang, Elizabeth E. Martelli, Kate Stenson, Conner P. Witherow, Judy Drazba, Srinivasan Dasarathy, Sathyamangla V. Naga Prasad
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Although microRNA-7 (miRNA-7) is known to regulate proliferation of cancer cells by targeting Epidermal growth factor receptor (EGFR/ERBB) family, less is known about its role in cardiac physiology. Transgenic (Tg) mouse with cardiomyocyte-s
Externí odkaz:
https://doaj.org/article/51f839007800465793b14c9b05827ac8
Autor:
Judy Drazba, Ajaykumar Zalavadia, Yu Sun, Kate Stenson, Xi Wang, Maradumane L. Mohan, Manveen K Gupta, Conner Witherow, Anita Sahu, Sathyamangla V. Naga Prasad, Avinash Kumar, Elizabeth E. Martelli, Srinivasan Dasarathy
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports
Scientific Reports
Although microRNA-7 (miRNA-7) is known to regulate proliferation of cancer cells by targeting Epidermal growth factor receptor (EGFR/ERBB) family, less is known about its role in cardiac physiology. Transgenic (Tg) mouse with cardiomyocyte-specific o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9230919847e1da0156881c62a84320b
https://doi.org/10.1038/s41598-021-00778-6
https://doi.org/10.1038/s41598-021-00778-6
Autor:
Conner Withrow, Elizabeth E Martelli, Xi Wang, Anita Sahu, Kate Stenson, Sathyamangla V. Naga Prasad, Manveen K Gupta
Role of microRNA-7 (miRNA-7) in targeting Epidermal growth factor receptor (EGFR/ERBB) family is known in dividing cancer cells while less is known about its role in terminally differentiated cardiac cells. We generated transgenic (Tg) mice with card
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecbcbdd7681b66b23655230758281c2f
https://doi.org/10.1101/2020.09.17.302224
https://doi.org/10.1101/2020.09.17.302224
ObjectiveTo understand the underlying pathways that promote cardiotoxicity following chemotherapy.BackgroundAnthracyclines are associated with cardiotoxicity which could be potentiated with use of complementary agents (like anti-ERBB2 inhibitors) whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01266d3a37a80ca10d2ad58436741dd4
https://doi.org/10.1101/2020.09.17.301689
https://doi.org/10.1101/2020.09.17.301689
Publikováno v:
SSRN Electronic Journal.
Objective: To determine the underlying pathways that promote cardiotoxicity following anti-ERBB2 cancer therapeutics. Background: Epidermal growth factor receptor 2 (EGFR2/ERBB2) is a member of EGFR (ERBB) family represented by ERBB 1 through 4 that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c40c0983276f499eb2d650d53e725cc
https://doi.org/10.2139/ssrn.3581890
https://doi.org/10.2139/ssrn.3581890
Autor:
Stephan Nieuwoudt, Ciaran E. Fealy, Elizabeth E. Martelli, Srinivasan Dasarathy, John P. Kirwan, Sathyamangla V. Naga Prasad, Anny Mulya
Publikováno v:
American Journal of Physiology-Cell Physiology. 313:C575-C583
We are interested in understanding mechanisms that govern the protective role of exercise against lipid-induced insulin resistance, a key driver of type 2 diabetes. In this context, cell culture models provide a level of abstraction that aid in our u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e879a383ad398d8cb96ddc42d202893e
https://doi.org/10.1152/ajpcell.00123.2017
https://doi.org/10.1152/ajpcell.00123.2017
Autor:
Sanjib Senapati, Madhulika Dixit, Durairajpandian Vishnuprabu, Ajit S. Mullasari, Viswanathan Mohan, Bhavani S. Sahu, Arasambattu Kannan Munirajan, Sathyamangla V. Naga Prasad, Rathnakumar Kumaragurubaran, Venkatesan Radha, Venkat R. Chirasani, Madhu Khullar, Malapaka Kiranmayi, Lakshmi Subramanian, Prasanna K.R. Allu, Saurabh Sharma, Elizabeth E Martelli, Nitish R. Mahapatra, Dhanasekaran Bodhini
Publikováno v:
Hypertension. 68:334-347
Catestatin (CST), an endogenous antihypertensive/antiadrenergic peptide, is a novel regulator of cardiovascular physiology. Here, we report case–control studies in 2 geographically/ethnically distinct Indian populations (n≈4000) that showed assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe0a58646fd98e843603b0f52746f2e
https://doi.org/10.1161/hypertensionaha.116.06568
https://doi.org/10.1161/hypertensionaha.116.06568
Autor:
Maradumane L Mohan, Lisa M Grove, Robert S Papay, Elizabeth E Martelli, Belinda B Willard, Mitchell A Olman, Sathyamangla V Naga Prasad
Publikováno v:
Circulation Research. 121
Phosphoinositide 3 Kinase γ (PI3Kγ) is a lipid kinase that regulates downstream anti-apoptotic Akt signaling. Thus, pressure overload in PI3Kγ null (PI3Kγ -/- ) mice leads to significant cardiac fibrosis, a key underlying cause of fatal heart fai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f8e085866121e681c0a2008051c8a58
https://doi.org/10.1161/res.121.suppl_1.109
https://doi.org/10.1161/res.121.suppl_1.109
Autor:
Vincent K. Tuohy, Nina Dvorina, Suparna Mazumder, Justin M. Johnson, Jennifer S. Ko, Valerie Swank, Elizabeth E. Martelli
Publikováno v:
Cancer prevention research (Philadelphia, Pa.). 10(11)
Epithelial ovarian carcinoma (EOC) is the most prevalent form of ovarian cancer in the United States, representing approximately 85% of all cases and causing more deaths than any other gynecologic malignancy. We propose that optimized control of EOC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55664b542a565af1a3c95a93ca6f1bcd
https://pubmed.ncbi.nlm.nih.gov/29093010
https://pubmed.ncbi.nlm.nih.gov/29093010
Autor:
Unnikrishnan M. Chandrasekharan, Paul E. DiCorleto, Elizabeth E Martelli, Sathyamangla V. Naga Prasad, Neelakantan T Vasudevan, Arthur M. Feldman, Yilu Qin, Manveen K Gupta, David Young, Subha Sen, Afshan K. Hussain, Maradumane L. Mohan, Gerald W. Dorn
Publikováno v:
Circulation. 128:377-387
Background— Proinflammatory cytokine tumor necrosis factor-α (TNFα) induces β-adrenergic receptor (βAR) desensitization, but mechanisms proximal to the receptor in contributing to cardiac dysfunction are not known. Methods and Results— Two di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c1b24faeb454593e86f6ef7056533dc
https://doi.org/10.1161/circulationaha.113.003183
https://doi.org/10.1161/circulationaha.113.003183