Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Elizabeth D. Frederick"'
Autor:
Yetti Mulugeta, Elizabeth D. Frederick, David Bar-Or, Raphael Bar-Or, Charles W. Mains, Gregory W. Thomas, Michael Roshon, Melissa Hausburg, Lisa Thompson
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-15 (2020)
Journal of Translational Medicine
Journal of Translational Medicine
Background Dysregulation of transcription and cytokine expression has been implicated in the pathogenesis of a variety inflammatory diseases. The resulting imbalance between inflammatory and resolving transcriptional programs can cause an overabundan
Background: The low molecular weight fraction of human serum albumin (LMWF5A) has immunomodulatory activity via its effects on multiple inflammatory mediators and is currently being evaluated for the treatment of hyperactive or persistent inflammator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2df5ca1049ddf650e89e37ac803263c5
https://doi.org/10.21203/rs.3.rs-790987/v2
https://doi.org/10.21203/rs.3.rs-790987/v2
The low molecular weight fraction of human serum albumin (LMWF5A) has proven immunomodulatory activity via its effects on multiple inflammatory mediators and transcription factors. This biologic drug is currently being evaluated for the treatment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fe66ac2e90ec85f913b2666b82011c9
https://doi.org/10.21203/rs.3.rs-790987/v1
https://doi.org/10.21203/rs.3.rs-790987/v1
Autor:
Edward Brody, Elizabeth D. Frederick, David Bar-Or, Leonard T. Rael, Gregory W. Thomas, Raphael Bar-Or, Melissa Hausburg
Publikováno v:
Current Rheumatology Reviews
The low molecular weight fraction of commercial human serum albumin (LMWF5A) has been shown to successfully relieve pain and inflammation in severe osteoarthritis of the knee (OAK). LMWF5A contains at least three active components that could account
Autor:
Marshall Hoke, David Bar-Or, Charles W. Mains, Laura Goldberg, Gregory W. Thomas, Elizabeth D. Frederick, Michael Roshon, Melissa Hausburg
Publikováno v:
Patient Safety in Surgery
Patient Safety in Surgery, Vol 14, Iss 1, Pp 1-11 (2020)
Patient safety in surgery, 14(1):21
Patient Safety in Surgery, Vol 14, Iss 1, Pp 1-11 (2020)
Patient safety in surgery, 14(1):21
Background A common complication of viral pulmonary infections, such as in the ongoing COVID-19 pandemic, is a phenomenon described as a “cytokine storm”. While poorly defined, this hyperinflammatory response results in diffuse alveolar damage. T
Autor:
Elizabeth D. Frederick, Leonard T. Rael, Gregory W. Thomas, David Bar-Or, Edward Brody, Melissa Hausburg
Publikováno v:
Biochemical and Biophysical Research Communications. 478:1780-1785
It has long been appreciated that the microtubule network plays a critical role in endothelial cell function. Chemical inhibition of tubulin polymerization has been shown to drastically increases endothelial permeability via interactions with the act
Autor:
Leonard T. Rael, Elizabeth D. Frederick, Matthew M. Carrick, Gregory W. Thomas, Denetta S. Slone, David Bar-Or, Melissa Hausburg, Charles W. Mains
Publikováno v:
Biochemical and Biophysical Research Communications. 473:1328-1333
Activation of the innate immune system involves a series of events designed to counteract the initial insult followed by the clearance of debris and promotion of healing. Aberrant regulation can lead to systemic inflammatory response syndrome, multip
Autor:
Melissa A, Hausburg, Elizabeth D, Frederick, Patrick, McNair, John, Schwappach, Kaysie L, Banton, Michael, Roshon, Mark J, Lieser, David L, Acuna, Rahul R, Banerjee, David, Bar-Or
Publikováno v:
Clinical and experimental rheumatology. 36(5)
Traumatic joint injury induces chondrocyte dysfunction and progressive breakdown of articular cartilage, leading to post-traumatic osteoarthritis (PTOA). In this condition, dysfunctional fibroblast-like chondrocytes (FLCs) no longer express proteins
Autor:
David Bar-Or, Leonard T. Rael, Elizabeth D. Frederick, Edward Brody, Gregory W. Thomas, Melissa Hausburg
Publikováno v:
Biochemistry and Biophysics Reports
Background The ability to decrease inflammation and promote healing is important in the intervention and management of a variety of disease states, including osteoarthritis of the knee (OAK). Even though cyclooxygenase 2 (COX2) has an established pro
Publikováno v:
Chemical Research in Toxicology. 17:1057-1063
Diepoxybutane, diepoxyoctane, and mechlorethamine are cytotoxic agents that induce interstrand cross-links between the N7 positions of deoxyguanosine residues on opposite strands of the DNA duplex preferentially at 5'-GNC sequences. We have systemati