Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Elizabeth D, Hughes"'
Autor:
Jin Chen, Lingjun Zhang, Maojing Yang, Elizabeth D. Hughes, Zachary T. Freeman, Thomas L. Saunders, Feng Lin
Publikováno v:
Journal of Innate Immunity, Pp 1-1 (2023)
Introduction: C3 is central for all complement activation pathways, thus an attractive therapeutic target. Many C3-targeted agents are under extensive development with one already approved for clinical use. However, most, if not all, C3 inhibitors ar
Externí odkaz:
https://doaj.org/article/c531a0589394406ca02d9b8770b9cade
Autor:
Di Chen, Elizabeth D. Hughes, Thomas L. Saunders, Jiangping Wu, Magda N. Hernandez Vasquez, Taija Makinen, Philip D. King
Publikováno v:
JCI Insight, Vol 7, Iss 4 (2022)
Capillary malformation-arteriovenous malformation (CM-AVM) is a blood vascular anomaly caused by inherited loss-of-function mutations in RASA1 or EPHB4 genes, which encode p120 Ras GTPase-activating protein (p120 RasGAP/RASA1) and Ephrin receptor B4
Externí odkaz:
https://doaj.org/article/14d3deb285e046a59b5decf8cbfb1be2
Autor:
Jessica A Lehoczky, Peedikayil E Thomas, Kevin M Patrie, Kailey M Owens, Lisa M Villarreal, Kenneth Galbraith, Joe Washburn, Craig N Johnson, Bryant Gavino, Alexander D Borowsky, Kathleen J Millen, Paul Wakenight, William Law, Margaret L Van Keuren, Galina Gavrilina, Elizabeth D Hughes, Thomas L Saunders, Lesil Brihn, Joseph H Nadeau, Jeffrey W Innis
Publikováno v:
PLoS Genetics, Vol 9, Iss 12, p e1003967 (2013)
Mouse early transposon insertions are responsible for ~10% of spontaneous mutant phenotypes. We previously reported the phenotypes and genetic mapping of Polypodia, (Ppd), a spontaneous, X-linked dominant mutation with profound effects on body plan m
Externí odkaz:
https://doaj.org/article/7e2168f239154d7b8e91247117543900
Autor:
Rashmi Budhathoki, Claire Peabody, Sandra Camelo-Piragua, Thomas L. Saunders, Philip Chi-En Huang, Ester Calvo Fernandez, Tao Xu, Elizabeth D. Hughes, Brian Magnuson, Jean François Rual, Rork Kuick, Honglai Zhang
Publikováno v:
Neuro Oncol
The NOTCH/RBPJ pathway governs cell proliferation in many biological contexts, including SHH and Group#3medulloblastoma (MB) tumorigenesis. Using our proteomic platform, we discovered an interaction between RBPJ, a key co-factor of NOTCH for the modu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e110b90a2bf30a695d79ba08dcdc5c
https://europepmc.org/articles/PMC7650321/
https://europepmc.org/articles/PMC7650321/
Autor:
Christopher J. Sinal, Hannah Garver, Thomas L. Saunders, Elizabeth D. Hughes, David J. Ferland, Michael G. Zeidler, Emma S. Darios, Wanda E. Filipiak, Nichole McMullen, Ramya K. Kumar, Adam E. Mullick, Gregory D. Fink, Stephanie W. Watts
Publikováno v:
The FASEB Journal. 32:6596-6614
Measures of the adipokine chemerin are elevated in multiple cardiovascular diseases, including hypertension, but little mechanistic work has been done to implicate chemerin as being causative in such diseases. The chemerin knockout (KO) rat was creat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62109c30223669edacd031f85a1b6e55
https://doi.org/10.1096/fj.201800479
https://doi.org/10.1096/fj.201800479
Publikováno v:
Journal of Bacteriology. 201
During its life cycle, the environmental pathogen Legionella pneumophila alternates between a replicative and transmissive cell type when cultured in broth, macrophages, or amoebae. Within a protozoan host, L. pneumophila further differentiates into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ce2ced1ee29e358c2603b6e129c65c
https://doi.org/10.1128/jb.00253-19
https://doi.org/10.1128/jb.00253-19
Autor:
Wanda E, Filipiak, Elizabeth D, Hughes, Galina B, Gavrilina, Anna K, LaForest, Thomas L, Saunders
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2018
The next generation of new genetically engineered rat models by microinjection is described. Genome editors such as CRISPR/Cas9 have greatly increased the efficiency with which the rat genome can be modified to generate research models for biomedical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c530edae709d2af20a3e147b34fa9bf1
https://pubmed.ncbi.nlm.nih.gov/31228153
https://pubmed.ncbi.nlm.nih.gov/31228153
During its life cycle, the environmental pathogenLegionella pneumophilaalternates between a replicative and a transmissive cell type when cultured in broth, macrophages, or amoebae. Within a protozoan host,L. pneumophilafurther differentiates into th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef3e6c657c5d41e7c38d5c0ee30a3319
Autor:
Anna K LaForest, Wanda E. Filipiak, Galina B. Gavrilina, Elizabeth D. Hughes, Thomas L. Saunders
Publikováno v:
Methods in Molecular Biology ISBN: 9781493995806
The next generation of new genetically engineered rat models by microinjection is described. Genome editors such as CRISPR/Cas9 have greatly increased the efficiency with which the rat genome can be modified to generate research models for biomedical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0382c14c1cba45a3506dc784015ec539
https://doi.org/10.1007/978-1-4939-9581-3_4
https://doi.org/10.1007/978-1-4939-9581-3_4
Autor:
Bradley A. Thrasher, Deepukumar M. Nair, James M. Parisi, William E. McKinzie, Elizabeth D. Hughes, Michael A. Smith
Publikováno v:
IEEE Antennas and Wireless Propagation Letters. 15:1522-1525
This letter presents a 60-GHz $2 \times 2$ low temperature co-fired ceramic (LTCC) aperture-coupled patch antenna array with an integrated Sievenpiper electromagnetic band-gap (EBG) structure used to suppress TM-mode surface waves. The merit of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::670f30571afee21c75a5b936f41f91a7
https://doi.org/10.1109/lawp.2016.2517141
https://doi.org/10.1109/lawp.2016.2517141