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pro vyhledávání: '"Elizabeth C Upton"'
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210627 (2019)
VanS is a membrane-bound sensor histidine kinase responsible for sensing vancomycin and activating transcription of vancomycin-resistance genes. In the presence of vancomycin, VanS phosphorylates the transcription factor VanR, converting it to its tr
Externí odkaz:
https://doaj.org/article/8ecc8df841e444a8892eeea191988990
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 1, p e0210627 (2019)
PLoS ONE, Vol 14, Iss 1, p e0210627 (2019)
VanS is a membrane-bound sensor histidine kinase responsible for sensing vancomycin and activating transcription of vancomycin-resistance genes. In the presence of vancomycin, VanS phosphorylates the transcription factor VanR, converting it to its tr
Autor:
Elizabeth C. Upton, Karyn McFadden, Navid Madani, Andrew P. Holmes, Isaac Zentner, Ferit Tuzer, Srivats Rajagopal, Kantharaju Kamanna, Judith M. LaLonde, Joseph Sodroski, Mark Contarino, Irwin Chaiken
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 81:271-290
Despite advances in HIV therapy, viral resistance and side-effects with current drug regimens require targeting new components of the virus. Dual antagonist peptide triazoles (PT) are a novel class of HIV-1 inhibitors that specifically target the gp1
Publikováno v:
Journal of Trauma: Injury, Infection & Critical Care. 65:929-932
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (5):1199-1207
Tyrocidine A, one of the first antibiotics ever to be discovered, is a cyclic decapeptide that binds to membranes of target bacteria, disrupting their integrity. It is active against a broad spectrum of Gram-positive organisms, and has recently engen