Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Elizabeth C O'Quinn"'
Autor:
Lyndsay E. A. Young, Paul J. Nietert, Rachel Stubler, Caroline G. Kittrell, Grace Grimsley, David N. Lewin, Anand S. Mehta, Chadi Hajar, Katherine Wang, Elizabeth C. O’Quinn, Peggi M. Angel, Kristin Wallace, Richard R. Drake
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Colorectal cancer (CRC) stands as a leading cause of death worldwide, often arising from specific genetic mutations, progressing from pre-cancerous adenomas to adenocarcinomas. Early detection through regular screening can result in a 90% 5-year surv
Externí odkaz:
https://doaj.org/article/2a26f4a5a123444dbc5e34be62f87024
Autor:
Sixue Liu, Hannah M. Knochelmann, Shirley H. Lomeli, Aayoung Hong, Mary Richardson, Zhentao Yang, Raymond J. Lim, Yan Wang, Camelia Dumitras, Kostyantyn Krysan, Cynthia Timmers, Martin J. Romeo, Carsten Krieg, Elizabeth C. O’Quinn, Joshua D. Horton, Steve M. Dubinett, Chrystal M. Paulos, David M. Neskey, Roger S. Lo
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 10, Pp 100411- (2021)
Summary: Neoadjuvant PD-1 blockade may be efficacious in some individuals with high-risk, resectable oral cavity head and neck cancer. To explore correlates of response patterns to neoadjuvant nivolumab treatment and post-surgical recurrences, we ana
Externí odkaz:
https://doaj.org/article/39a1c3a08dca431b9aeaf1eb80b12cdf
Autor:
Hannah M. Knochelmann, Joshua D. Horton, Sixue Liu, Kent Armeson, John M. Kaczmar, Megan M. Wyatt, Mary S. Richardson, Shirley H. Lomeli, Ying Xiong, Evan M. Graboyes, Eric J. Lentsch, Joshua D. Hornig, Judith Skoner, Seth Stalcup, Maria V. Spampinato, Elizabeth Garrett-Mayer, Elizabeth C. O’Quinn, Cynthia D. Timmers, Martin J. Romeo, John M. Wrangle, M. Rita I. Young, Mark P. Rubinstein, Terry A. Day, Roger S. Lo, Chrystal M. Paulos, David M. Neskey
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 10, Pp 100426- (2021)
Summary: Oral cavity squamous cell carcinoma (OCSCC) is a prevalent surgically treated subset of head and neck cancer with frequent recurrence and poor survival. Immunotherapy has demonstrated efficacy in recurrent/metastatic head and neck cancer. Ho
Externí odkaz:
https://doaj.org/article/106d0eef51b345229c78936aef78ee40
Autor:
Ozge Saatci, Ozge Akbulut, Metin Cetin, Vitali Sikirzhytski, Meral Uner, Deniz Lengerli, Elizabeth C. O’Quinn, Martin J. Romeo, Burcu Caliskan, Erden Banoglu, Sercan Aksoy, Aysegul Uner, Ozgur Sahin
Publikováno v:
Cell Death & Differentiation. 30:1305-1319
Centrosome amplification (CA) is a hallmark of cancer that is strongly associated with highly aggressive disease and worse clinical outcome. Clustering extra centrosomes is a major coping mechanism required for faithful mitosis of cancer cells with C
Autor:
Roger S. Lo, S. Dubinett, Elizabeth C O'Quinn, Shirley H. Lomeli, Hannah M. Knochelmann, Mary S. Richardson, Raymond J. Lim, Cynthia D Timmers, Sixue Liu, Camelia Dumitras, David M. Neskey, Carsten Krieg, Aayoung Hong, Yan Wang, Martin J. Romeo, Kostyantyn Krysan, Chrystal M. Paulos, Joshua D. Horton, Zhentao Yang
Publikováno v:
Cell Reports Medicine
Cell Reports Medicine, Vol 2, Iss 10, Pp 100411-(2021)
Cell Reports Medicine, Vol 2, Iss 10, Pp 100411-(2021)
Summary Neoadjuvant PD-1 blockade may be efficacious in some individuals with high-risk, resectable oral cavity head and neck cancer. To explore correlates of response patterns to neoadjuvant nivolumab treatment and post-surgical recurrences, we anal
Autor:
Maria Vittoria Spampinato, John M. Kaczmar, Elizabeth C O'Quinn, Martin J. Romeo, Roger S. Lo, Cynthia Timmers, John Wrangle, Eric J. Lentsch, Kent Armeson, Hannah M. Knochelmann, Ying Xiong, Terry A. Day, M. Rita I. Young, Seth Stalcup, Mary S. Richardson, Joshua D. Horton, Shirley H. Lomeli, David M. Neskey, Evan M. Graboyes, Judith M. Skoner, Sixue Liu, Elizabeth Garrett-Mayer, Mark P Rubinstein, Megan Wyatt, Joshua D. Hornig, Chrystal M. Paulos
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 10, Pp 100426-(2021)
Cell Reports Medicine
Cell Reports Medicine
Summary Oral cavity squamous cell carcinoma (OCSCC) is a prevalent surgically treated subset of head and neck cancer with frequent recurrence and poor survival. Immunotherapy has demonstrated efficacy in recurrent/metastatic head and neck cancer. How
Autor:
Elizabeth C O'Quinn, Chetan A. Patil, Xiaohong Bi, Conor C. Lynch, Jeffry S. Nyman, Anita Mahadevan-Jansen, George M. Pharr, Daniel S. Perrien, Sophie Thiolloy, Gregory R. Mundy
Publikováno v:
Journal of Bone and Mineral Research. 26:1252-1260
Matrix metalloproteinases (MMPs) are capable of processing certain components of bone tissue, including type 1 collagen, a determinant of the biomechanical properties of bone tissue, and they are expressed by osteoclasts and osteoblasts. Therefore, w
Autor:
Elizabeth C O'Quinn, Gregory R. Mundy, James R. Edwards, Javier Esparza, Scott Lonning, Swati Biswas, Chetan A. Patil, Jeffry S. Nyman, Megan M Moore, Seint T. Lwin, Andrew J. Hart, Anita Mahadevan-Jansen
Publikováno v:
Journal of Bone and Mineral Research. 25:2419-2426
Transforming growth factor β (TGF-β) is an abundant bone matrix protein that influences osteoblast and osteoclast interactions to control bone remodeling. As such, TGF-β represents an obvious pharmacologic target with the potential to regulate bot
Autor:
Kannan Kunchithapautham, Gloriane Schnabolk, Beth Coughlin, Bärbel Rohrer, Kimberly Stauffer, Elizabeth C O'Quinn
Age-related macular degeneration (AMD) is the most prevalent cause of blindness in the elderly. To study potential underlying mechanisms of AMD, animal models are utilized, focusing mostly on mice. Recently, genomic and phenotypic differences between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6e74b6913ebdfd1221255bdb1902331
https://europepmc.org/articles/PMC5710800/
https://europepmc.org/articles/PMC5710800/
Autor:
Joseph H. Gorman, John S. Ikonomidis, Jeremy L. Barth, Laurel Black, Robert E. Stroud, John A. Elefteriades, Robert C. Gorman, Francis G. Spinale, Elizabeth C O'Quinn, Joseph E. Bavaria, Jeffrey A. Jones
Background— Increasing evidence points to a direct role for altered microRNA (miRNA or miR) expression levels in cardiovascular remodeling and disease progression. Although alterations in miR expression levels have been directly linked to cardiac h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81737ee9eac8051cbc711c3e01e131d0
https://europepmc.org/articles/PMC3246193/
https://europepmc.org/articles/PMC3246193/