Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Elizabeth Barto"'
Autor:
Yuqing Deng, Jacob Herrmann, Yu Wang, Minh Nguyen, Joseph K. Hall, Jae Hun Kim, Michael L. Smith, Kenneth R. Lutchen, Elizabeth Bartolák-Suki, Béla Suki
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Collagen fibers, one of the key load-bearing components of the extracellular matrix, contribute significantly to tissue integrity through their mechanical properties of strain-dependent stiffening. This study investigated the effects of bact
Externí odkaz:
https://doaj.org/article/ceb658dec55f41ebaa1dbb85e8c2a6f9
Autor:
Crismita Dmello, Junfei Zhao, Li Chen, Andrew Gould, Brandyn Castro, Victor A. Arrieta, Daniel Y. Zhang, Kwang-Soo Kim, Deepak Kanojia, Peng Zhang, Jason Miska, Ragini Yeeravalli, Karl Habashy, Ruth Saganty, Seong Jae Kang, Jawad Fares, Connor Liu, Gavin Dunn, Elizabeth Bartom, Matthew J. Schipma, Patrick D. Hsu, Mahmoud S. Alghamri, Maciej S. Lesniak, Amy B. Heimberger, Raul Rabadan, Catalina Lee-Chang, Adam M. Sonabend
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Immunotherapies have shown limited efficacy in patients with glioma. Here, based on an in vivo kinome knockout CRISPR screen, the authors show that checkpoint kinase 2 promotes CD8 T cell immune evasion and that its depletion or inhibition improve su
Externí odkaz:
https://doaj.org/article/add0ff19941e4f458a8e86e32cf2095c
Autor:
Tina Yi-Ting Huang, Andrea Piunti, Jin Qi, Marc Morgan, Elizabeth Bartom, Ali Shilatifard, Amanda M. Saratsis
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-13 (2020)
Abstract Histone H3.3 mutation (H3F3A) occurs in 50% of cortical pediatric high-grade gliomas. This mutation replaces glycine 34 with arginine or valine (G34R/V), impairing SETD2 activity (H3K36-specific trimethyltransferase). Consequently, reduced H
Externí odkaz:
https://doaj.org/article/dcbb1c3fc7df43c0a5fd0aa7be97d7ea
Autor:
Zhiqiang Du, Jeniece Regan, Elizabeth Bartom, Wei-Sheng Wu, Li Zhang, Dustin Kenneth Goncharoff, Liming Li
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-20 (2020)
Abstract Transcriptional regulators are prevalent among identified prions in Saccharomyces cerevisiae, however, it is unclear how prions affect genome-wide transcription. We show here that the prion ([SWI +]) and mutant (swi1∆) forms of Swi1, a sub
Externí odkaz:
https://doaj.org/article/5e69ff4896f947ceb52123ff6e314899
Autor:
Wenhao Zhao, Shuhua Wu, Elizabeth Barton, Yongjian Fan, Yinghua Ji, Xiaofeng Wang, Yijun Zhou
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Geminiviruses are an important group of circular, single-stranded DNA viruses that cause devastating diseases in crops. Geminiviruses replicate their genomic DNA in the nucleus and the newly synthesized viral DNA is subsequently transported to the cy
Externí odkaz:
https://doaj.org/article/3b6c5ff95a2f4958bbd480565373159e
Autor:
Jarred R. Mondoñedo, Elizabeth Bartolák-Suki, Samer Bou Jawde, Kara Nelson, Kun Cao, Adam Sonnenberg, Walter Patrick Obrochta, Jasmin Imsirovic, Sumati Ram-Mohan, Ramaswamy Krishnan, Béla Suki
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
RationalePrecision-cut lung slices (PCLSs) are a valuable tool in studying tissue responses to an acute exposure; however, cyclic stretching may be necessary to recapitulate physiologic, tidal breathing conditions.ObjectivesTo develop a multi-well st
Externí odkaz:
https://doaj.org/article/f3f4cff538894481bc17ddf275c08609
Autor:
Andrea E. Calvert, Alexandra Chalastanis, Yongfei Wu, Lisa A. Hurley, Fotini M. Kouri, Yingtao Bi, Maureen Kachman, Jasmine L. May, Elizabeth Bartom, Youjia Hua, Rama K. Mishra, Gary E. Schiltz, Oleksii Dubrovskyi, Andrew P. Mazar, Marcus E. Peter, Hongwu Zheng, C. David James, Charles F. Burant, Navdeep S. Chandel, Ramana V. Davuluri, Craig Horbinski, Alexander H. Stegh
Publikováno v:
Cell Reports, Vol 19, Iss 9, Pp 1858-1873 (2017)
Oncogenic mutations in two isocitrate dehydrogenase (IDH)-encoding genes (IDH1 and IDH2) have been identified in acute myelogenous leukemia, low-grade glioma, and secondary glioblastoma (GBM). Our in silico and wet-bench analyses indicate that non-mu
Externí odkaz:
https://doaj.org/article/f4d292ac8f8346f8ab26ed8e258f99d4
Publikováno v:
Molecules, Vol 26, Iss 1, p 11 (2020)
NAD+ (nicotinamide adenine dinucleotide)-dependent protein deacylases, namely, the sirtuins, are important cell adaptor proteins that alter cell physiology in response to low calorie conditions. They are thought to mediate the beneficial effects of c
Externí odkaz:
https://doaj.org/article/4cdf12b35cff42a3b082e91acee2f121
Publikováno v:
Animal Behaviour. 11:40-50
Measures of behaviour of three strains of deermice ( Peromyscus maniculatus ) which exhibit inherited types of convulsions or whirling are compared with similar measures made of a normal strain. Differences between affected and normal strains occur i
Autor:
R. R. Huestis, Elizabeth Barto
Publikováno v:
Journal of Heredity. 27:73-76