Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Elizabeth Ballantyne"'
Autor:
James A. Simon, Richard A. Anderson, Elizabeth Ballantyne, James Bolognese, Cecilia Caetano, Hadine Joffe, Mary Kerr, Nick Panay, Christian Seitz, Susan Seymore, Mike Trower, Lineke Zuurman, Steve Pawsey
Publikováno v:
Simon, J A, Anderson, R A, Ballantyne, E, Bolognese, J, Caetano, C, Joffe, H, Kerr, M, Panay, N, Seitz, C, Seymore, S, Trower, M, Zuurman, L & Pawsey, S 2023, ' Efficacy and safety of elinzanetant, a selective neurokinin-1,3 receptor antagonist for vasomotor symptoms: a dose-finding clinical trial (SWITCH-1) ', Menopause . https://doi.org/10.1097/GME.0000000000002138
Objective Neurokinin (NK)-3 and NK-1 receptors have been implicated in the etiology of vasomotor symptoms (VMS) and sleep disturbances associated with menopause. This phase 2b, adaptive, dose-range finding study aimed to assess the efficacy and safet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc9f531434258a66ce71f536338a9fd7
https://www.pure.ed.ac.uk/ws/files/327901912/Efficacy_and_safety_of_elinzanetant_a_selective.146.pdf
https://www.pure.ed.ac.uk/ws/files/327901912/Efficacy_and_safety_of_elinzanetant_a_selective.146.pdf
Autor:
Elizabeth Ballantyne, Richard A. Anderson, Mike Trower, Steve Pawsey, Mary Kerr, Hadine Joffe
Publikováno v:
Trower, M, Anderson, R, Ballantyne, E, Joffe, H, Kerr, M & Pawsey, S 2020, ' Effects of NT-814, a dual neurokinin 1 and 3 receptor antagonist, on vasomotor symptoms in postmenopausal women: a placebo-controlled, randomized controlled trial ', Menopause . https://doi.org/10.1097/GME.0000000000001500
Menopause (New York, N.y.)
Menopause (New York, N.y.)
Objectives: To evaluate the safety, pharmacokinetics, and preliminary efficacy of NT-814, a dual neurokinin 1,3 antagonist, in postmenopausal women with vasomotor symptoms (hot flashes). Methods: We completed a double-blind, randomized, placebo-contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a6fef2fb73abffe9fbb5795bd9a126a
https://doi.org/10.1097/gme.0000000000001500
https://doi.org/10.1097/gme.0000000000001500
Autor:
Elizabeth Ballantyne, Kirsteen Donaldson, Mike Trower, Waljit S. Dhillo, Mary Kerr, Steve Pawsey, Edouard Mills
Publikováno v:
The Journal of Clinical Endocrinology and Metabolism
Context The ideal therapy for endometriosis (EM) and uterine fibroids (UFs) would suppress estrogenic drive to the endometrium and myometrium, while minimizing vasomotor symptoms and bone loss associated with current treatments. An integrated neuroki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6e43f55466c3707db02fa5cc924297
https://pubmed.ncbi.nlm.nih.gov/33846737
https://pubmed.ncbi.nlm.nih.gov/33846737
Autor:
Steve Pawsey, Elizabeth Ballantyne, Kirsteen Donaldson, Mary Kerr, Mike Trower, Waljit S. Dhillo
Publikováno v:
Journal of the Endocrine Society
Introduction: Uterine fibroids (UF) affect up to 25% of women and endometriosis (EM) 10% of women worldwide. An ideal therapy would lower estradiol concentrations to reduce hormonal drive to the endometrium and myometrium, but not to the levels which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21271826bf7b6f7b3c256c8943c47d27
http://europepmc.org/articles/PMC7209475
http://europepmc.org/articles/PMC7209475
Autor:
Steve Pawsey, Mike Trower, Hadine Joffe, Elizabeth Ballantyne, Richard A. Anderson, Susan Seymore, Mary Kerr, James A. Simon
Publikováno v:
Journal of the Endocrine Society
Introduction: Vasomotor symptoms (VMS), caused by declining estrogen in menopausal women, are common and debilitating. Hormone therapy is effective in many women but carries risks and may be contraindicated. Biological and clinical evidence shows a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab427f598ee79dfd3373d55a18248704
https://doi.org/10.1210/jendso/bvaa046.2071
https://doi.org/10.1210/jendso/bvaa046.2071
Autor:
Mandel Sher, Lorcan McGarvey, Mary Kerr, Stephen Pawsey, Michael K. Trower, Alyn H. Morice, Jaclyn A. Smith, Elizabeth Ballantyne
Publikováno v:
Clinical Problems.
Background: No proven therapies exist for refractory chronic cough (CC). Neurokinin(NK)-1 antagonists may modulate the central neural hypersensitivity causing CC. The NK-1 antagonist orvepitant was assessed in CC in a Phase 2b dose-ranging study. Met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0af188f58d97752d57ceae66afc24593
https://doi.org/10.1183/13993003.congress-2019.pa600
https://doi.org/10.1183/13993003.congress-2019.pa600
Autor:
Rod Harvey, Frances Beards, Sian Ellard, Maggie Appleton, Elizabeth Ballantyne, Andrew T. Hattersley
Publikováno v:
Nature genetics. 19(3)
Low birth weight and fetal thinness have been associated with non-insulin dependent diabetes mellitus (NIDDM) and insulin resistance in childhood and adulthood. It has been proposed that this association results from fetal programming in response to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d918ffa961be10f1c23023e78745930a
https://pubmed.ncbi.nlm.nih.gov/9662384
https://pubmed.ncbi.nlm.nih.gov/9662384
Autor:
Simon, James A., Anderson, Richard A., Ballantyne, Elizabeth, Bolognese, James, Caetano, Cecilia, Joffe, Hadine, Kerr, Mary, Panay, Nick, Seitz, Christian, Seymore, Susan, Trower, Mike, Zuurman, Lineke, Pawsey, Steve
Publikováno v:
Menopause (10723714); Mar2023, Vol. 30 Issue 3, p239-246, 8p
Autor:
Pawsey, Steve, Mills, Edouard Gregory, Ballantyne, Elizabeth, Donaldson, Kirsteen, Kerr, Mary, Trower, Mike, Dhillo, Waljit Singh
Publikováno v:
Journal of Clinical Endocrinology & Metabolism; Aug2021, Vol. 106 Issue 8, pe3221-e234, 14p
Publikováno v:
Menopause (10723714); Dec2020, Vol. 27 Issue 12, p1447-1475, 29p