Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Elizabeth B. Smedley"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Sign-tracking is a conditioned response where animals interact with reward-predictive cues due to the cues having motivational value, or incentive salience. The nucleus accumbens core (NAc) has been implicated in mediating the sign-tracking
Externí odkaz:
https://doaj.org/article/a3d47716f262429c87a47586528b116b
Sign-tracking is a conditioned response where animals interact with reward-predictive cues and can be used as a means to approximate a cue’s motivational value. The nucleus accumbens core (NAc) has been highly implicated in mediating the sign-track
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c9cd46c3912d7ed76b3b6e8353e4012
https://doi.org/10.1101/2022.12.22.521615
https://doi.org/10.1101/2022.12.22.521615
Autor:
Wilder T. Doucette, Elizabeth B. Smedley, Metztli Ruiz-Jaquez, Jibran Y. Khokhar, Kyle S. Smith
Publikováno v:
Brain Res
Current treatments for obesity do not reliably reduce body weight over time. New interventional strategies, including chemogenetics, carry promise based on preclinical animal studies. Here, we focused on the ventral pallidum (VP) due to its clearly e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4bdc99463f45983e233c860de60e1f3
https://europepmc.org/articles/PMC9161366/
https://europepmc.org/articles/PMC9161366/
Autor:
Jibran Y. Khokhar, Wilder T. Doucette, Kyle S. Smith, Metztli J. Ruiz-Jaquez, Elizabeth B. Smedley
Current treatments for obesity are unable to reliably reduce weight over time and alternative treatments need to address this challenge. New interventions that target the nervous system could manipulate brain networks underlying reward, metabolic rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::628fe4aef400512019775af2634705e2
Autor:
Hannah L. Mayberry, Heather A. DeSalvo, Charlotte C. Bavley, Sara H. Downey, Cindy Lam, Charita Kunta, Ricardo P. Fortuna, Priya H. Doshi, Elizabeth B. Smedley, Mathieu E. Wimmer
Publikováno v:
eneuro. 9:ENEURO.0515-21.2022
Incubation of craving refers to the intensification of drug-seeking behavior in response to reward-paired cues over the course of abstinence. In rodents, craving and drug-seeking behaviors have been measured by an increase in lever pressing in the ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f4cef81bf85aeae17f1f95116b3e231
https://doi.org/10.1523/eneuro.0515-21.2022
https://doi.org/10.1523/eneuro.0515-21.2022
Autor:
Jeffrey J. Stott, Katherine J. Stansfield, Elizabeth B. Smedley, Stephen E. Chang, Kyle S. Smith
Publikováno v:
The Journal of Neuroscience. 37:5670-5680
Salt appetite, in which animals can immediately seek out salt when under a novel state of sodium deprivation, is a classic example of how homeostatic systems interface with learned associations to produce an on-the-fly updating of motivated behavior.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e86448461d8f60f3b2a92e3f19d3d9b
https://doi.org/10.1523/jneurosci.2968-16.2017
https://doi.org/10.1523/jneurosci.2968-16.2017
Publikováno v:
Binge Eating ISBN: 9783030435615
It is an exciting time to study the neurobiological basis of binge-eating behavior, as innovative techniques to manipulate the brain are allowing for novel and more targeted treatment approaches to be evaluated. While some of these techniques are cur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eef46b7779fb0875a1660fed6b7693fc
https://doi.org/10.1007/978-3-030-43562-2_8
https://doi.org/10.1007/978-3-030-43562-2_8
Sign-tracking is a form of autoshaping where by animals reliably develop conditioned responses toward stimuli that predict an outcome. While the assignment of some value to a predictive cue may be adaptive (i.e., to be alerted to food and water sourc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ca73428e8e280d4e0ab8c3c9040d0a
https://doi.org/10.1101/475541
https://doi.org/10.1101/475541
Publikováno v:
Neurobiol Learn Mem
Sign-tracking behavior, in which animals interact with a cue that predicts reward, provides an example of how incentive salience can be attributed to cues and elicit motivation. The nucleus accumbens (NAc) and ventral pallidum (VP) are two regions in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ad8dd34996ead4102c0c0108972cc3
Autor:
Kyle S. Smith, Elizabeth B. Smedley
Publikováno v:
Behav Processes
Sign-tracking is a phenomenon whereby cues that predict rewards come to acquire their own motivational value (incentive salience) and attract appetitive behavior. Typically, sign-tracking paradigms have used single auditory, visual, or lever cues pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f414dd5669b1832bd3e078457a1ae4a3
https://europepmc.org/articles/PMC9206823/
https://europepmc.org/articles/PMC9206823/