Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Elizabeth B. Neely"'
Publikováno v:
Fluids and Barriers of the CNS, Vol 19, Iss 1, Pp 1-10 (2022)
Abstract Background The brain requires iron for a number of processes, including energy production. Inadequate or excessive amounts of iron can be detrimental and lead to a number of neurological disorders. As such, regulation of brain iron uptake is
Externí odkaz:
https://doaj.org/article/f0ff6eb5fcb84770986126f54fddb6a5
Autor:
Marcelo R. S. Briones, Amanda M. Snyder, Renata C. Ferreira, Elizabeth B. Neely, James R. Connor, James R. Broach
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
Amyotrophic lateral sclerosis (ALS) is the third most prevalent neurodegenerative disease affecting upper and lower motor neurons. An important pathway that may lead to motor neuron degeneration is neuroinflammation. Cerebrospinal Fluids of ALS patie
Externí odkaz:
https://doaj.org/article/713c1b85546c4f1c989b99024da2c51e
Publikováno v:
J Neurochem
Iron delivery to the developing brain is essential for energy and metabolic support needed for processes such as myelination and neuronal development. Iron deficiency, especially in the developing brain, can result in a number of long-term neurologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddbbb766f8df4a041a17a66b7386fae3
https://doi.org/10.1111/jnc.14834
https://doi.org/10.1111/jnc.14834
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-10 (2019)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background Inappropriate contact between the immune system and the central nervous system is thought to be a cause of demyelination. We previously reported the ability of the class IV semaphorin, Semaphorin4A (Sema4A), to induce apoptosis in human ol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f483db90bfedd9c2a5dfc67b44d11b
http://link.springer.com/article/10.1186/s12974-019-1420-9
http://link.springer.com/article/10.1186/s12974-019-1420-9
Autor:
Mechelle M. Lewis, Gregory L. Brown, Elizabeth B. Neely, Leslie C Jellen, Guangwei Du, Ernest W. Wang, James R. Connor, Hairong Chen, Max L Trojano, Lan Kong, Insung Song, Xuemei Huang
Publikováno v:
Toxicol Sci
Paraquat is an herbicide whose use is associated with Parkinson’s disease (PD), a neurodegenerative disorder marked by neuron loss in the substantia nigra pars compacta (SNc). We recently observed that the murine homolog to the human H63D variant o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1acb1c08ba21ada96642372fd818028d
https://pubmed.ncbi.nlm.nih.gov/33739421
https://pubmed.ncbi.nlm.nih.gov/33739421
Autor:
Qing X. Yang, Jianli Wang, Carson J. Purnell, Elizabeth B. Neely, Paul J. Eslinger, Mark D. Meadowcroft, James R. Connor
Publikováno v:
Journal of Neuroimaging. 28:126-133
Background and purpose The H63D-HFE single nucleotide polymorphism (SNP) has been associated with brain iron dysregulation; however, the emergent role of this missense variant in brain structure and function has yet to be determined. Previous work ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::663fcd1f1db7e40fa893eaeec14a3b9c
https://doi.org/10.1111/jon.12461
https://doi.org/10.1111/jon.12461
Publikováno v:
Muscle & Nerve. 54:284-291
Introduction HMG-CoA reductase inhibitors (statins) and H63D HFE polymorphism may modify amyotrophic lateral sclerosis (ALS). We hypothesized that statins worsen phenotype in ALS mice, dependent on HFE genotype. Methods Mice harboring SOD1(G93A) hete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16d62339feefe8acbaef42765848aac7
https://doi.org/10.1002/mus.25048
https://doi.org/10.1002/mus.25048
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::488eca1f1a42ec25b22618cf5a7f0a54
https://doi.org/10.1096/fasebj.2018.32.1_supplement.782.18
https://doi.org/10.1096/fasebj.2018.32.1_supplement.782.18
Autor:
James R. Broach, James R. Connor, Amanda M. Snyder, Elizabeth B. Neely, Marcelo R S Briones, Renata C. Ferreira
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
Frontiers in Neurology
Frontiers in Neurology
Amyotrophic lateral sclerosis (ALS) is the third most prevalent neurodegenerative disease affecting upper and lower motor neurons. An important pathway that may lead to motor neuron degeneration is neuroinflammation. Cerebrospinal Fluids of ALS patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fef809dc72b823524c3b9cb6cdfa5f3
http://journal.frontiersin.org/article/10.3389/fneur.2018.00039/full
http://journal.frontiersin.org/article/10.3389/fneur.2018.00039/full
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-11 (2018)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background Iron regulation is essential for cellular energy production. Loss of cellular iron homeostasis has critical implications for both normal function and disease progression. The H63D variant of the HFE gene is the most common gene variant in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38f2b709f3064d0d88c7114bd276cd9c
https://doi.org/10.1186/s12974-018-1057-0
https://doi.org/10.1186/s12974-018-1057-0