Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Elizabeth Anne Kuo"'
Autor:
Erik Ruuthb, Richard A. Williamson, Yea Christopher Martyn, T. Andrew Thomson, Elizabeth Anne Kuo, Robert Westwood, Adam P. Curnock
Publikováno v:
Biochemical Pharmacology. 61:227-235
HR325 (2-cyano-3-cyclopropyl-3-hydroxy- N -[3′-methyl-4′(trifluoromethyl)-phenyl]-propenamide) is an immunomodulatory compound through pyrimidine biosynthesis inhibition with antiproliferative properties which was derived from the isoxazol compou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e425d786409a4e2d7d454eb6abe299d
https://doi.org/10.1016/s0006-2952(00)00552-9
https://doi.org/10.1016/s0006-2952(00)00552-9
Autor:
Catherine Sautes, Richard A. Williamson, Erik Ruuth, Claude Fudali, Peter A. Robson, Elizabeth Anne Kuo, Jean-Michel Bruneau, Katherine Woodward, Robert Westwood, Sylviane Spinella-Jaegle, Yea Christopher Martyn
Publikováno v:
Biochemical Journal. 336:299-303
Leflunomide is currently in phase-III clinical trials for the treatment of rheumatoid arthritis. In this study, we have focused our efforts on the study of the mechanism of action of the active metabolite of leflunomide, A77 1726, in cells and tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c03d369f43e17c391b41722f8b52edd9
https://doi.org/10.1042/bj3360299
https://doi.org/10.1042/bj3360299