Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Elizabeth Ahern"'
Autor:
Mark A. Kroenke, Marta Starcevic Manning, Christina L. Zuch de Zafra, Xinwen Zhang, Kevin D. Cook, Michael Archer, Martijn P. Lolkema, Jin Wang, Sarah Hoofring, Gurleen Saini, Famke Aeffner, Elizabeth Ahern, Elena Garralda Cabanas, Ramaswamy Govindan, Mun Hui, Shalini Gupta, Daniel T. Mytych
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/72f24fcbd43448008d13f236f8a3523a
Autor:
Mark A. Kroenke, Marta Starcevic Manning, Christina L. Zuch de Zafra, Xinwen Zhang, Kevin D. Cook, Michael Archer, Martijn P. Lolkema, Jin Wang, Sarah Hoofring, Gurleen Saini, Famke Aeffner, Elizabeth Ahern, Elena Garralda Cabanas, Ramaswamy Govindan, Mun Hui, Shalini Gupta, Daniel T. Mytych
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
AMG 256 is a bi-specific, heteroimmunoglobulin molecule with an anti-PD-1 antibody domain and a single IL-21 mutein domain on the C-terminus. Nonclinical studies in cynomolgus monkeys revealed that AMG 256 administration led to the development of imm
Externí odkaz:
https://doaj.org/article/9a833fe6e7534142a8fff16ef8164fb5
Autor:
Andrew Haydon, John Powderly, Timothy Wyant, James Vasselli, Drew Rasco, Meredith McKean, Elizabeth Ahern, Sophia Frentzas, Andrew Weickhardt, Inbar Amit, Aron Knickerbocker, Yanay Ofran, Paul de Souza, Jenny Tang, Lori Richards
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/cac7820b4bd0445e9e32670fae38d1ab
Autor:
Lucy Gately, Katharine Drummond, Mark Rosenthal, Rosemary Harrup, Anthony Dowling, Andrew Gogos, Zarnie Lwin, Ian Collins, David Campbell, Elizabeth Ahern, Claire Phillips, Hui K. Gan, Iwan Bennett, Oliver M. Sieber, Peter Gibbs
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Real-world data (RWD) is increasingly being embraced as an invaluable source of information to address clinical and policy-relevant questions that are unlikely to ever be answered by clinical trials. However, the largely unrealise
Externí odkaz:
https://doaj.org/article/dde2958b8619435fbac30562014e21eb
Autor:
Amy Body, Elizabeth Ahern, Luxi Lal, Karen Gillett, Hesham Abdulla, Stephen Opat, Tracey O’Brien, Peter Downie, Stuart Turville, C. Mee Ling Munier, Corey Smith, C. Raina MacIntyre, Eva Segelov
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Cancer is associated with excess morbidity and mortality from coronavirus disease 2019 (COVID-19) following infection by the novel pandemic coronavirus SARS-CoV-2. Vaccinations against SARS-CoV-2 have been rapidly developed and pr
Externí odkaz:
https://doaj.org/article/8b813284b7c74424a818cf795772aacf
Autor:
Wen Juan Tu, Robert D. McCuaig, Michelle Melino, Daniel J. Rawle, Thuy T. Le, Kexin Yan, Andreas Suhrbier, Rebecca L. Johnston, Lambros T. Koufariotis, Nicola Waddell, Emily M. Cross, Sofiya Tsimbalyuk, Amanda Bain, Elizabeth Ahern, Natasha Collinson, Simon Phipps, Jade K. Forwood, Nabila Seddiki, Sudha Rao
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-25 (2021)
Abstract Treatment options for COVID-19 remain limited, especially during the early or asymptomatic phase. Here, we report a novel SARS-CoV-2 viral replication mechanism mediated by interactions between ACE2 and the epigenetic eraser enzyme LSD1, and
Externí odkaz:
https://doaj.org/article/94d2222dd5d142eaabe147edc4a852eb
Publikováno v:
BMJ Open, Vol 12, Iss 4 (2022)
Introduction Clinical trials are the backbone of research. It is well recognised that patient participation in clinical trials can be influenced by a myriad of factors such as access to a clinical trial, restrictive trial eligibility criteria and per
Externí odkaz:
https://doaj.org/article/ca76fcfe4a9b439e9faa945fffd59090
Autor:
Elizabeth Ahern, Annette Cubitt, Emma Ballard, Michele W. L. Teng, William C. Dougall, Mark J. Smyth, David Godbolt, Rishendran Naidoo, Amanda Goldrick, Brett G. M. Hughes
Publikováno v:
Trials, Vol 20, Iss 1, Pp 1-9 (2019)
Abstract Background Neoadjuvant immunotherapy targeting immune checkpoint programmed death-1 (PD-1) is under investigation in various tumour settings including non-small-cell lung cancer (NSCLC). Preclinical models demonstrate the superior power of t
Externí odkaz:
https://doaj.org/article/9117ce33194c46a382e8341cd7f4cfdf
Autor:
Amy Body, Vivienne Milch, Lynda McSorley, Luxi Lal, Elizabeth Ahern, Regina Ryan, Gayle Jones, Dorothy Keefe, Eva Segelov
Publikováno v:
Vaccines, Vol 10, Iss 12, p 2003 (2022)
Background: COVID-19 is an unprecedented global health emergency. It has been highly disruptive for patients with cancer, both due to an increased burden of severe illness and due to pressure on healthcare systems. COVID-19 vaccination has been an im
Externí odkaz:
https://doaj.org/article/72c1d3ba4a474a408a201631333b645f
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Standard curative treatment of early-stage non-small cell lung cancer (NSCLC) involves surgery in combination with postoperative (adjuvant) platinum-based chemotherapy where indicated. Preoperative (neoadjuvant) therapies offer certain theoretical be
Externí odkaz:
https://doaj.org/article/ec837e9b3b5f4dbf8ea3e671b4a7873d