Výsledky vyhledávání - "Elizabeth A. Vokac"

The role of the D1 domain of the von Willebrand factor propeptide in multimerization of VWF

Autor: Elizabeth A. Vokac, Yohko Kawai, Scot A. Fahs, Sandra L. Haberichter, Jonathan B. Rosenberg, Philip A. Kroner, Mary A. Jozwiak, Robert R. Montgomery

Publikováno v: Blood. 100:1699-1706

While studying patient plasma containing an unusual pattern of von Willebrand factor (VWF) multimers, we discovered a previously unreported phenomenon: heavy predominance of dimeric VWF. Genomic analysis revealed a new congenital mutation (Tyr87Ser)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cb5e16c5c77aade6ff0f9f53d29be4d
https://doi.org/10.1182/blood-2002-03-0789

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Intracellular trafficking of factor VIII to von Willebrand factor storage granules

Autor: Paul A. Foster, Robert R. Montgomery, R J Kaufman, Jonathan B. Rosenberg, Elizabeth A. Vokac, M Moussalli, Philip A. Kroner

Publikováno v: Journal of Clinical Investigation. 101:613-624

In plasma, von Willebrand factor (vWf) associates with Factor VIII (FVIII); however, the site at which these proteins first interact has not been defined. Administration of 1-desamino-8-D-arginine vasopressin (DDAVP) causes a rapid, concomitant eleva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a529cc1076be198d30e86f79b59a6c
https://doi.org/10.1172/jci1250

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Type 2M:Milwaukee-1 von Willebrand disease: an in-frame deletion in the Cys509-Cys695 loop of the von Willebrand factor A1 domain causes deficient binding of von Willebrand factor to platelets

Autor: Pamela A. Christopherson, Robert R. Montgomery, Philip A. Kroner, Joan Cox Gill, David J. Mancuso, Elizabeth A. Vokac

Publikováno v: Blood. 88:2559-2568

This report examines the genetic basis of a variant form of moderately severe von Willebrand disease (vWD) characterized by low plasma von Willebrand factor antigen (vWF:Ag) levels and normal multimerization, typical of type 1 vWD, but disproportiona

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3de68f792b490b0ae8040f80d2859907
https://doi.org/10.1182/blood.v88.7.2559.bloodjournal8872559

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Von Willebrand antigen II (vWAgII) distinguishes acquired von Willebrand Syndrome (AvWS) due to decreased synthesis from that due to increased clearance of vWF. † 795

Autor: Elizabeth A. Vokac, Joan Cox Gill, J. Paul Scott, Kenneth D. Friedman, Robert R. Montgomery

Publikováno v: Pediatric Research. 43:138-138

Acquired von Willebrand syndrome (AvWS) is bleeding disorder that develops de novo in an individual with a negative past personal and family history of bleeding in association with laboratory studies indicative of von Willebrand disease. This diagnos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::83a62a9a4aee866ec68ab637910d9005
https://doi.org/10.1203/00006450-199804001-00816

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PRODUCTION OF HUMAN MONOCLONAL ANTIBODIESSPECIFIC FOR PLATELET MEMBRANE GLYCOPROTEIN IIIa

Autor: Thomas J. Kunicki, Kenichi Furihata, Diane J. Nugent, Amy L Bissonette, Elizabeth A. Vokac

Publikováno v: XIth International Congress on Thrombosis and Haemostasis.

Human monoclonal antibodies specific for platelet membrane glycoproteins (GPs) arepotentially important reagentsfor studies of the immunogenicity of membrane glycoproteins. A human monoclonalautoantibody, 5E5, reactive with plateletGPIIIa has been de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ba63f00ac999bc61bc6606fe89f747f6
https://doi.org/10.1055/s-0038-1643705

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