Zobrazeno 1 - 10
of 877
pro vyhledávání: '"Elizabeth A. Thompson"'
Autor:
Katerina Roznik, Jiashu Xue, Georgia Stavrakis, T. Scott Johnston, Divya Kalluri, Rivka Ohsie, Caroline X. Qin, John McAteer, Dorry L. Segev, Douglas Mogul, William A. Werbel, Andrew H. Karaba, Elizabeth A. Thompson, Andrea L. Cox
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-18 (2024)
Abstract Immune responses to COVID-19 vaccination are attenuated in adult solid organ transplant recipients (SOTRs) and additional vaccine doses are recommended for this population. However, whether COVID-19 mRNA vaccine responses are limited in pedi
Externí odkaz:
https://doaj.org/article/6568a698357547dba4965e74b984681c
Autor:
Jenny M. Lee, Alexis Figueroa, Jaiprasath Sachithanandham, Maggie Li, Caoilfhionn M. Connolly, Janna R. Shapiro, Yiqun Chen, Michelle Jones, Venkata Gayatri Dhara, Marilyn Towns, John S. Lee, Stephanie R. Peralta, Aaron M. Milstone, Michael Betenbaugh, Amanda K. Debes, Joel Blankson, Ioannis Sitaras, Steve Yoon, Elizabeth A. Thompson, Clifton O. Bingham, Sabra L. Klein, Andrew Pekosz, Justin R. Bailey
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Patients with inflammatory arthritis (IA) are at increased risk of severe COVID-19 due to medication-induced immunosuppression that impairs host defenses. The aim of this study was to assess antibody and B cell responses to COVID-19 mRNA vaccination
Externí odkaz:
https://doaj.org/article/1ec2cd452f3f47fe824a3fbe8bc7e429
Autor:
Kyungho Lee, Elizabeth A. Thompson, Sepideh Gharaie, Chirag H. Patel, Johanna T. Kurzhagen, Phillip M. Pierorazio, Lois J. Arend, Ajit G. Thomas, Sanjeev Noel, Barbara S. Slusher, Hamid Rabb
Publikováno v:
JCI Insight, Vol 8, Iss 12 (2023)
T cells play an important role in acute kidney injury (AKI). Metabolic programming of T cells regulates their function, is a rapidly emerging field, and is unknown in AKI. We induced ischemic AKI in C57BL/6J mice and collected kidneys and spleens at
Externí odkaz:
https://doaj.org/article/ab487db4fbcf47a9b1dfc8335f75d4e6
Autor:
Elizabeth A. Thompson, Wabathi Ngecu, Laila Stoddart, Trevor S. Johnston, Amy Chang, Katherine Cascino, Jennifer L. Alejo, Aura T. Abedon, Hady Samaha, Nadine Rouphael, Aaron A.R. Tobian, Dorry L. Segev, William A. Werbel, Andrew H. Karaba, Joel N. Blankson, Andrea L. Cox
Publikováno v:
JCI Insight, Vol 8, Iss 10 (2023)
Background The SARS-CoV-2 Omicron BA.5 subvariant escapes vaccination-induced neutralizing antibodies because of mutations in the spike (S) protein. Solid organ transplant recipients (SOTRs) develop high COVID-19 morbidity and poor Omicron variant re
Externí odkaz:
https://doaj.org/article/e8d780e4cc6f4b38b75c9f84671d049b
Autor:
Alvaro A. Ordonez, C. Korin Bullen, Andres F. Villabona-Rueda, Elizabeth A. Thompson, Mitchell L. Turner, Vanessa F. Merino, Yu Yan, John Kim, Stephanie L. Davis, Oliver Komm, Jonathan D. Powell, Franco R. D’Alessio, Robert H. Yolken, Sanjay K. Jain, Lorraine Jones-Brando
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
Sulforaphane, a chemical found in broccoli, has known antioxidant and antiinflammatory effects. Here, the authors show that it can inhibit SARS-CoV-2 and other coronavirus infections in mammalian cells and can decrease viral load in mice when treated
Externí odkaz:
https://doaj.org/article/a6ee1679bea84b2b98163a24fb77681b
Autor:
Laura A. Sena, Rajendra Kumar, David E. Sanin, Elizabeth A. Thompson, D. Marc Rosen, Susan L. Dalrymple, Lizamma Antony, Yuhan Yang, Carolina Gomes-Alexandre, Jessica L. Hicks, Tracy Jones, Kiara A. Bowers, Jillian N. Eskra, Jennifer Meyers, Anuj Gupta, Alyza Skaist, Srinivasan Yegnasubramanian, Jun Luo, W. Nathaniel Brennen, Sushant K. Kachhap, Emmanuel S. Antonarakis, Angelo M. De Marzo, John T. Isaacs, Mark C. Markowski, Samuel R. Denmeade
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 23 (2022)
Testosterone is the canonical growth factor of prostate cancer but can paradoxically suppress its growth when present at supraphysiological levels. We have previously demonstrated that the cyclical administration of supraphysiological androgen (SPA),
Externí odkaz:
https://doaj.org/article/1190b8e3606d4217ab6c491c95462033
Autor:
Kariem Ezzat, Maria Pernemalm, Sandra Pålsson, Thomas C. Roberts, Peter Järver, Aleksandra Dondalska, Burcu Bestas, Michal J. Sobkowiak, Bettina Levänen, Magnus Sköld, Elizabeth A. Thompson, Osama Saher, Otto K. Kari, Tatu Lajunen, Eva Sverremark Ekström, Caroline Nilsson, Yevheniia Ishchenko, Tarja Malm, Matthew J. A. Wood, Ultan F. Power, Sergej Masich, Anders Lindén, Johan K. Sandberg, Janne Lehtiö, Anna-Lena Spetz, Samir EL Andaloussi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
The protein corona around artificial nanoparticles is known to influence activity and biological fate, the formation around viruses is less well understood. Here, the authors observe the formation of protein corona on viruses and study the effects th
Externí odkaz:
https://doaj.org/article/707b1edf615a4fe08fe6eacaded85b36
Autor:
Sebastian Ols, Lifei Yang, Elizabeth A. Thompson, Pradeepa Pushparaj, Karen Tran, Frank Liang, Ang Lin, Bengt Eriksson, Gunilla B. Karlsson Hedestam, Richard T. Wyatt, Karin Loré
Publikováno v:
Cell Reports, Vol 30, Iss 12, Pp 3964-3971.e7 (2020)
Summary: Although intramuscular (i.m.) administration is the most commonly used route for licensed vaccines, subcutaneous (s.c.) delivery is being explored for several new vaccines under development. Here, we use rhesus macaques, physiologically rele
Externí odkaz:
https://doaj.org/article/1d7a952cbf3f415099b8e5cefd3a2f70
Autor:
Katherine S. Duke, Alexia J. Taylor-Just, Mark D. Ihrie, Kelly A. Shipkowski, Elizabeth A. Thompson, Erinn C. Dandley, Gregory N. Parsons, James C. Bonner
Publikováno v:
Particle and Fibre Toxicology, Vol 14, Iss 1, Pp 1-15 (2017)
Abstract Background Pulmonary toxicity of multi-walled carbon nanotubes (MWCNTs) is influenced by physicochemical characteristics and genetic susceptibility. We hypothesized that contrasting rigidities of tangled (t) versus rod-like (r) MWCNTs would
Externí odkaz:
https://doaj.org/article/82db27a85b2c42aa9bc1cc5e352c93b0
Autor:
Elizabeth A. Thompson, Patricia A. Darrah, Kathryn E. Foulds, Elena Hoffer, Alayna Caffrey-Carr, Sophie Norenstedt, Leif Perbeck, Robert A. Seder, Ross M. Kedl, Karin Loré
Publikováno v:
Cell Reports, Vol 28, Iss 5, Pp 1127-1135.e4 (2019)
Summary: Using non-human primates (NHPs), mice, and human primary cells, we found a role for interleukin-10 (IL-10) in the upregulation of the tissue-resident memory T cell (TRM) marker CD103. In NHPs, intravenous, but not subcutaneous, immunization
Externí odkaz:
https://doaj.org/article/8414394f6b7d4b949f761c63d98542d3