Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Elizabeth A. Saria"'
Autor:
Jessica Costa-Guda, Robert Romano, Samip Shah, Kristin R. Corrado, Madison Rose, Justin Bellizzi, Elizabeth A. Saria, Sanjay M. Mallya, Andrew Arnold, Kirsten Saucier, Cynthia B Alander
Publikováno v:
Endocrinology
The protein product of the cyclin D1 oncogene functions by activating partner cyclin-dependent kinases (cdk)4 or cdk6 to phosphorylate, thereby inactivating, the retinoblastoma protein pRB. Nonclassical, cdk-independent, functions of cyclin D1 have b
Autor:
Andrew Arnold, Sanjay M. Mallya, Kristin R. Corrado, Elizabeth A. Saria, Huy Tran, Kirsten Saucier, Sotirios Tetradis, Feng-ning Frank Yuan, Elisa Atti
Publikováno v:
Endocrine research, vol 41, iss 4
Purpose: We sought to develop and characterize a model of human vitamin D nutritional insufficiency/deficiency in the adult mouse, which could have broad utility in examining health consequences of this common condition. Methods: Adult mice were fed
Publikováno v:
Journal of Cellular Physiology. 230:2951-2960
Bone remodeling requires osteoclast activation, resorption, and reversal, prior to osteoblast migration into the bone pit. The Receptor Activator of NF-κB (RANK) signaling pathway plays an important role in bone remodeling. Two components of the RAN
Autor:
Paolo Fortina, Erik S. Knudsen, Emanuele Loro, Zhiping Li, Zuoren Yu, Marco Crosariol, Andrew Arnold, Elizabeth A. Saria, Gabriele Di Sante, Richard G. Pestell, Chenguang Wang, Alexandros Papanikolaou, Robert D. Cardiff, Michael P. Lisanti, Adam Ertel, Aydin Tozeren, Mathew C. Casimiro, Sankar Addya, Will Dampier
Publikováno v:
Oncotarget
Oncotarget, vol 6, iss 11
Oncotarget, vol 6, iss 11
Cyclin D1 is an important molecular driver of human breast cancer but better understanding of its oncogenic mechanisms is needed, especially to enhance efforts in targeted therapeutics. Currently, pharmaceutical initiatives to inhibit cyclin D1 are f
Autor:
Chenguang Wang, Richard G. Pestell, Emanuele Loro, Alexandros Papanikolaou, Zuoren Yu, Adam Ertel, Sankar Addya, Paolo Fortina, Zhaoming Li, Will Dampier, Erik S. Knudsen, Elizabeth A. Saria, Mathew C. Casimiro, Marco Crosariol, Andrew Arnold, Michael P. Lisanti, G Di Sante, Aydin Tozeren
Publikováno v:
Cancer Research. 73:P5-07
Cyclin D1 is an important molecular driver of human breast cancer but better understanding of its oncogenic mechanisms is needed, especially to enhance efforts in targeted therapeutics. Activation of the cyclin D1 oncogene, often by amplification or
Autor:
Margaret Seton, Jennifer D. Akunowicz, Robin J. Leach, John D Delaney, Nimit Patel, Anand Merchant, Elizabeth A. Saria, Magda Smielewska, Marc F. Hansen
Publikováno v:
Journal of Bone and Mineral Research. 24:484-494
Paget's disease of bone (PDB) is a focal disorder of bone remodeling that leads to overgrowth of affected bone, with rare progression to osteosarcoma. Extensive studies of familial PDB showed that a majority of cases harbor germline mutations in the
Autor:
Glenn S. Belinsky, Thiruchandurai V. Rajan, Elizabeth A. Saria, Charles Giardina, Daniel W. Rosenberg
Publikováno v:
Molecular Carcinogenesis. 46:106-116
Secretory phospholipase A2 (sPLA2-IIA) has been shown to attenuate intestinal tumorigenesis in Apc(Min) mice, demonstrating that it is a tumor modifier. To further explore the actions of sPLA2-IIA in tumorigenesis, sPLA2-IIA was overexpressed in two
Autor:
Jennifer D. Akunowicz, Marc F. Hansen, Elizabeth A. Saria, Bina B. Patel, Robin J. Leach, Richard Gorlick, Amit M. Deshpande, Xavier T. Reveles, Susan L. Naylor
Publikováno v:
Oncogene. 26:1714-1722
PHC3, a component of the hPRC-H complex, associates with E2F6 during G 0 and is lost in osteosarcoma tumors
Publikováno v:
Journal of cellular physiology. 230(12)
Bone remodeling requires osteoclast activation, resorption, and reversal, prior to osteoblast migration into the bone pit. The Receptor Activator of NF-κB (RANK) signaling pathway plays an important role in bone remodeling. Two components of the RAN
Autor:
Christopher R. Shea, Julie E. Allee, Elizabeth A. Saria, Neil S. Prose, Victor G. Prieto, Dennis Rosenblum
Publikováno v:
Journal of Cutaneous Pathology. 28:383-386
Background: Epidermal necrosis in a neonate is an uncommon event with a variety of potential cases. Result: We report a case of intrauterine epidermal necrosis in a preterm infant, with death occurring soon after birth. The histopathology of the denu