Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Elizabeth A. Rutledge"'
Autor:
Jenna C. Schabacker, Stephen J. Amish, Bonnie K. Ellis, Beth Gardner, Dulaney L. Miller, Elizabeth A. Rutledge, Adam J. Sepulveda, Gordon Luikart
Publikováno v:
Environmental DNA, Vol 2, Iss 2, Pp 244-251 (2020)
Abstract Environmental DNA analysis has revolutionized the way we study rare, invasive, and endangered taxa. However, if eDNA testing is to become an increasingly reliable tool, high detection sensitivity is crucial. Current eDNA sampling methods, li
Externí odkaz:
https://doaj.org/article/862baca3ffd24855b852248853a1e68c
Autor:
Stephen J. Amish, Gordon Luikart, Adam J. Sepulveda, Bonnie K. Ellis, Dulaney L. Miller, Elizabeth A. Rutledge, Jenna Schabacker, Beth Gardner
Publikováno v:
Environmental DNA, Vol 2, Iss 2, Pp 244-251 (2020)
Environmental DNA analysis has revolutionized the way we study rare, invasive, and endangered taxa. However, if eDNA testing is to become an increasingly reliable tool, high detection sensitivity is crucial. Current eDNA sampling methods, like filtra
Autor:
Daniel H. Moralejo, William R. A. Osborne, Richard A. Jensen, Jessica M. Fuller, Anne E. Kwitek, Brian Van Yserloo, Ruth A. Ettinger, Åke Lernmark, Elizabeth A. Rutledge
Publikováno v:
Life Sciences; 89(19-20), pp 748-754 (2011)
Aims: The Gimap gene family has been shown to be integral to T cell survival and development. A frameshift mutation in Gimap5, one of seven members of the Gimap family, results in lymphopenia and is a prerequisite for spontaneous type 1 diabetes (T1D
Autor:
Steven D. Chessler, Ian R. Sweet, B Van Yserloo, T. R. Hall, Arthur T. Suckow, Elizabeth A. Rutledge, Megan A. Waldrop
Publikováno v:
Journal of Molecular Endocrinology. 36:187-199
Pancreatic islets are unique outside the nervous system in that they contain high levels of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), synthesized by the enzyme glutamic acid decarboxylase (GAD). Since the role that GABA plays in
Autor:
Vinod Sommandas, Åke Lernmark, Brian Van Yserloo, Elizabeth A. Rutledge, Hemmo A. Drexhage, Jessica M. Fuller
Publikováno v:
Journal of Autoimmunity, 25(1), 1-12. Academic Press
BB-Diabetes Prone (BB-DP) rats, a model for endocrine autoimmune diseases, are severely lymphopenic, especially lacking ART2+ regulatory T cells. BB-Diabetes Resistant (DR) rats are not lymphopenic and do not develop autoimmunity. BB-DP and BB-DR rat
Autor:
Teresa Michalkiewicz, Åke Lernmark, Eric S. Lander, Jessica M. Fuller, Brian Van Yserloo, Ruth A. Ettinger, Anne E. Kwitek, Howard J. Jacob, Armand J. MacMurray, Elizabeth A. Rutledge, Mieczyslaw Michalkiewicz, Daniel H. Moralejo
Publikováno v:
Physiological Genomics. 19:228-232
A single point mutation in a novel immune-associated nucleotide gene 5 ( Ian5) coincides with severe T cell lymphopenia in BB rats. We used a transgenic rescue approach in lymphopenic BB-derived congenic F344. lyp/ lyp rats to determine whether this
Autor:
Anna Pettersson, Anne E. Kwitek, Bruce W. Birren, Howard J. Jacob, Armand J. MacMurray, Eric S. Lander, Ruth A. Ettinger, Sabine Bieg, Terri Daniels, Brian Van Yserloo, Elizabeth A. Rutledge, Sara J. Speros, Jessica M. Fuller, Åke Lernmark, Paul Gohlke, Ben Snyder, Kimberly Orlebeke, Daniel H. Moralejo, Jonathan B. Schaefer, Jianjie Jiang
Publikováno v:
Lund University
The BB (BioBreeding) rat is one of the best models of spontaneous autoimmune diabetes and is used to study non-MHC loci contributing to Type 1 diabetes. Type 1 diabetes in the diabetes-prone BB (BBDP) rat is polygenic, dependent upon mutations at sev
Autor:
James M. Allen, Elizabeth A. Rutledge, A. Dusty Miller, Christine L. Halbert, David W. Russell
Publikováno v:
Journal of Virology. 74:1524-1532
Vectors derived from adeno-associated virus type 2 (AAV2) promote gene transfer and expression in the lung; however, we have found that while gene expression can persist for at least 8 months in mice, it was reduced dramatically in rabbits over a per
Publikováno v:
Journal of Virology. 71:8429-8436
Vectors derived from adeno-associated virus (AAV) have the potential to stably transduce mammalian cells by integrating into host chromosomes. Despite active research on the use of AAV vectors for gene therapy, the structure of integrated vector prov
Publikováno v:
Journal of Cellular Physiology. 168:284-293
A soluble form of the human transferrin receptor (TfR) resulting from proteolytic cleavage at Arg 100 has been measured in human blood. In tissue culture cells elimination of the O-linked carbohydrate at Thr 104, four amino acids from the cleavage si