Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Elizabeth A. Rondini"'
Autor:
Lasse K. Markussen, Elizabeth A. Rondini, Olivia Sveidahl Johansen, Jesper G. S. Madsen, Elahu G. Sustarsic, Ann-Britt Marcher, Jacob B. Hansen, Zachary Gerhart-Hines, James G. Granneman, Susanne Mandrup
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
β-Adrenergic signaling is a core regulator of brown adipocyte function. Here, the authors provide unbiased insight into the transcriptional network controlled by lipolysis in brown adipocytes, showing that lipolysis is required for much of the therm
Externí odkaz:
https://doaj.org/article/1e86f6f9fe4740609f82a4f4f6dca1cc
Autor:
Elizabeth A. Rondini, Vanesa D. Ramseyer, Rayanne B. Burl, Roger Pique-Regi, James G. Granneman
Publikováno v:
Molecular Metabolism, Vol 53, Iss , Pp 101307- (2021)
Objective: The current study addresses the cellular complexity and plasticity of subcutaneous (inguinal) white adipose tissue (iWAT) in mice during the critical periods of perinatal growth and establishment. Methods: We performed a large-scale single
Externí odkaz:
https://doaj.org/article/32f3476c295f49bd9483f4b6a2c47562
Publikováno v:
Journal of Nutrition and Metabolism, Vol 2012 (2012)
We previously demonstrated that black bean (BB) and soy flour (SF)-based diets inhibit azoxymethane (AOM)-induced colon cancer. The objective of this study was to identify genes altered by carcinogen treatment in normal-appearing colonic mucosa and t
Externí odkaz:
https://doaj.org/article/aa851fec9b9c4f19b9707b65201f9567
Publikováno v:
eLife. 11
Cold-exposure triggers neogenesis in classic interscapular brown adipose tissue (BAT) that involves activation of b1-adrenergic receptors, proliferation of PDGFRA+ adipose tissue stromal cells (ASCs), and recruitment of immune cells whose phenotypes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61f9d8fde5641ba97eb9967b3000774
https://doi.org/10.7554/elife.80167
https://doi.org/10.7554/elife.80167
Autor:
Judy A. Westrick, Nicholas J. Peraino, Philip C. Smith, Zofia Duniec-Dmuchowski, John K. Fallon, Elizabeth A. Rondini, Thomas A. Kocarek, Liberta Cuko, Asmita Pant, Elizabeth M. Wilson
Publikováno v:
Drug Metabolism and Disposition. 49:706-717
The squalene synthase inhibitor squalestatin 1 (Squal1) is a potent and efficacious inducer of CYP2B expression in primary cultured rat hepatocytes and rat liver. To determine whether Squal1 is also an inducer of human CYP2B, the effects of Squal1 tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74ba5648d20b2edd3de1a6452431113d
https://doi.org/10.1124/dmd.120.000341
https://doi.org/10.1124/dmd.120.000341
Autor:
Yeonho Son, Cheoljun Choi, Abhirup Saha, Ji-Hyun Park, Hyeonyeong Im, Yoon Keun Cho, Je Kyung Seong, Rayanne B. Burl, Elizabeth A. Rondini, James G. Granneman, Yun-Hee Lee
Publikováno v:
Metabolism: clinical and experimental. 130
The mobilization and catabolism of lipid energy is a central function of adipocytes that is under the control of the β-adrenergic signaling pathway, and defects in β-adrenergic signaling in adipocytes have been linked to obesity and obesity-related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5418b8a93164d5fa20ad5f983cac68c
https://pubmed.ncbi.nlm.nih.gov/35150731
https://pubmed.ncbi.nlm.nih.gov/35150731
Autor:
Lasse K. Markussen, Elizabeth A. Rondini, Olivia Sveidahl Johansen, Jesper G. S. Madsen, Elahu G. Sustarsic, Ann-Britt Marcher, Jacob B. Hansen, Zachary Gerhart-Hines, James G. Granneman, Susanne Mandrup
Publikováno v:
Markussen, L K, Rondini, E A, Johansen, O S, Madsen, J G S, Sustarsic, E G, Marcher, A B, Hansen, J B, Gerhart-Hines, Z, Granneman, J G & Mandrup, S 2022, ' Lipolysis regulates major transcriptional programs in brown adipocytes ', Nature Communications, vol. 13, no. 1, 3956 . https://doi.org/10.1038/s41467-022-31525-8
β-Adrenergic signaling is a core regulator of brown adipocyte function stimulating both lipolysis and transcription of thermogenic genes, thereby expanding the capacity for oxidative metabolism. We have used pharmacological inhibitors and a direct a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9e4203264800325d462a68a3c56422
https://pubmed.ncbi.nlm.nih.gov/35803907
https://pubmed.ncbi.nlm.nih.gov/35803907
Autor:
James G. Granneman, Elizabeth A. Rondini, Rayanne B. Burl, Roger Pique-Regi, Vanesa D. Ramseyer
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 53, Iss, Pp 101307-(2021)
Molecular Metabolism, Vol 53, Iss, Pp 101307-(2021)
Objective The current study addresses the cellular complexity and plasticity of subcutaneous (inguinal) white adipose tissue (iWAT) in mice during the critical periods of perinatal growth and establishment. Methods We performed a large-scale single c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66808a94ee280292797ae35636f7106b
https://doi.org/10.1016/j.molmet.2021.101307
https://doi.org/10.1016/j.molmet.2021.101307
Autor:
Cong-Cong Yin, Elizabeth A. Rondini, K Wagner, Joyce D. Reyes, James G. Granneman, Prahlad Parajuli, Jennifer B. Jacob, Wei-Zen Wei, Kuang Wei, Qing-Sheng Mi
Publikováno v:
Cancer Research. 81:2920-2920
Although humans are heterogeneous, evaluation of tumorigenesis and immunotherapy has relied on the use of inbred mouse strains, which may lead to biased results. In order to investigate the effect(s) of genetic background on tumor incidence and immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1941f8c1f0df6204a2194ef99fe248e9
https://doi.org/10.1158/1538-7445.am2021-2920
https://doi.org/10.1158/1538-7445.am2021-2920