Zobrazeno 1 - 10
of 373
pro vyhledávání: '"Elizabeth A. Raetz"'
Autor:
Sonali Narang, Yohana Ghebrechristos, Nikki A. Evensen, Nina Murrell, Sylwia Jasinski, Talia H. Ostrow, David T. Teachey, Elizabeth A. Raetz, Timothee Lionnet, Matthew Witkowski, Iannis Aifantis, Aristotelis Tsirigos, William L. Carroll
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Relapsed pediatric B-cell acute lymphoblastic leukemia (B-ALL) remains one of the leading causes of cancer mortality in children. We performed Hi-C, ATAC-seq, and RNA-seq on 12 matched diagnosis/relapse pediatric leukemia specimens to uncove
Externí odkaz:
https://doaj.org/article/fb1e74a501a7414f905b010548c71afa
Autor:
Erin M. Guest, John A. Kairalla, Meenakshi Devidas, Emily Hibbitts, Andrew J. Carroll, Nyla A. Heerema, Holly R. Kubaney, Margaret A. August, Sidharth Ramesh, Byunggil Yoo, Midhat S. Farooqi, Melinda G. Pauly, Daniel S. Wechsler, Rodney R. Miles, Joel M. Reid, Cynthia D. Kihei, Lia Gore, Elizabeth A. Raetz, Stephen P. Hunger, Mignon L. Loh, Patrick A. Brown
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Infants less than 1 year old diagnosed with KMT2A-rearranged (KMT2A-r) acute lymphoblastic leukemia (ALL) are at high risk of remission failure, relapse, and death due to leukemia, despite intensive therapies. Infant KMT2A-r ALL blasts are characteri
Externí odkaz:
https://doaj.org/article/b91198f427bc4dd39ad94aff06c2ddf3
Autor:
Caitlin W. Elgarten, John A. Kairalla, Joel C. Thompson, Tamara P. Miller, Cindy Wang, Susan Conway, Mignon L. Loh, Elizabeth A. Raetz, Sumit Gupta, Rachel E. Rau, Anne Angiolillo, Karen R. Rabin, Sarah Alexander
Publikováno v:
eJHaem, Vol 4, Iss 3, Pp 745-750 (2023)
Abstract Hematologic malignancy is a risk factor for severe coronavirus disease 2019 (COVID‐19) in adults; however, data specific to children with leukemia are limited. High‐quality infectious adverse event data from the ongoing Children's Oncolo
Externí odkaz:
https://doaj.org/article/57edae85d0ba4b3fbd3daa30c6697185
Autor:
Carolin Escherich, Wenan Chen, Wenjian Yang, David T. Teachey, Elizabeth A. Raetz, Meenakshi Devidas, Gang Wu, Kim E. Nichols, Hiroto Inaba, Ching-Hon Pui, Sima Jeha, Stephen P. Hunger, Mignon L. Loh, Jun J. Yang
Publikováno v:
HemaSphere, Vol 7, p e4470514 (2023)
Externí odkaz:
https://doaj.org/article/5e2dd0cd40d948078d5edb03d94e5a96
Autor:
Erin M. Guest, John A. Kairalla, Joanne M. Hilden, ZoAnn E. Dreyer, Andrew J. Carroll, Nyla A. Heerema, Cindy Y. Wang, Meenakshi Devidas, Lia Gore, Wanda L. Salzer, Naomi J. Winick, William L. Carroll, Elizabeth A. Raetz, Michael Borowitz, Mignon L. Loh, Stephen P. Hunger, Patrick A. Brown
Publikováno v:
Haematologica, Vol 107, Iss 5 (2022)
Externí odkaz:
https://doaj.org/article/6f75c85ff88943d48d1cd90df26deea7
Autor:
Jayaram Vijayakrishnan, Maoxiang Qian, James B. Studd, Wenjian Yang, Ben Kinnersley, Philip J. Law, Peter Broderick, Elizabeth A. Raetz, James Allan, Ching-Hon Pui, Ajay Vora, William E. Evans, Anthony Moorman, Allen Yeoh, Wentao Yang, Chunliang Li, Claus R. Bartram, Charles G. Mullighan, Martin Zimmerman, Stephen P. Hunger, Martin Schrappe, Mary V. Relling, Martin Stanulla, Mignon L. Loh, Richard S. Houlston, Jun J. Yang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
B-cell acute lymphoblastic leukaemia (B-ALL) is a common childhood cancer. Here, the authors conducted a meta-analysis with four genome-wide association studies, totalling 5,321 cases and 16,666 controls of European descent, identifying B-ALL risk lo
Externí odkaz:
https://doaj.org/article/fe499f58e3cb45709aa02c81074cf619
Autor:
Karen L. Bride, Hai Hu, Anastasia Tikhonova, Tori J. Fuller, Tiffaney L. Vincent, Rawan Shraim, Marilyn M. Li, William L. Carroll, Elizabeth A. Raetz, Iannis Aifantis, David T. Teachey
Publikováno v:
Haematologica, Vol 107, Iss 8 (2021)
Despite improvements in outcomes for children with B- and T-cell acute lymphoblastic leukemia (B-ALL and T-ALL), patients with resistant or relapsed disease fare poorly. Previous studies have demonstrated the essential role of cyclin D3 in T-ALL dise
Externí odkaz:
https://doaj.org/article/5de625346f4e411da1839face46afb2f
Autor:
Elizabeth A. Raetz, Mignon L. Loh, Meenakshi Devidas, Kelly Maloney, Leonard A. Mattano, Eric Larsen, Andrew Carroll, Nyla A. Heerema, Julie M. Gastier-Foster, Brent Wood, Michael J. Borowitz, Naomi Winick, Stephen P. Hunger, William L. Carroll
Publikováno v:
Haematologica, Vol 104, Iss 11 (2019)
Externí odkaz:
https://doaj.org/article/60b1113e01004bcca99ed4e4b7c4f636
Autor:
Michael J. Burke, Wanda L. Salzer, Meenakshi Devidas, Yunfeng Dai, Lia Gore, Joanne M. Hilden, Eric Larsen, Karen R. Rabin, Patrick A. Zweidler-McKay, Michael J. Borowitz, Brent Wood, Nyla A. Heerema, Andrew J. Carroll, Naomi Winick, William L. Carroll, Elizabeth A. Raetz, Mignon L. Loh, Stephen P. Hunger
Publikováno v:
Haematologica, Vol 104, Iss 5 (2019)
With modern chemotherapy, approximately 90% of patients with pediatric acute lymphoblastic leukemia are now cured. However, subsets of patients can be identified who remain at very high risk of relapse with expected 4-year disease-free survival rates
Externí odkaz:
https://doaj.org/article/400df5614bb0423c96a66827ab493ef8
Autor:
Gloria Paz Contreras Yametti, Talia H. Ostrow, Sylwia Jasinski, Elizabeth A. Raetz, William L. Carroll, Nikki A. Evensen
Publikováno v:
Cancers, Vol 13, Iss 8, p 1847 (2021)
Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer and advances in its clinical and laboratory biology have grown exponentially over the last few decades. Treatment outcome has improved steadily with over 90% of patients surviving
Externí odkaz:
https://doaj.org/article/5e96c8281a7a4030a3c38e1b49288867