Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Elizabeth A. Novotny"'
3
In vitro hematopoietic differentiation of mouse embryonic stem cells requires the tumor suppressor menin and is mediated by Hoxa9
Autor: Pengfei Liu, Francis S. Collins, Settara C. Chandrasekharappa, Elizabeth A. Novotny, Sheila T. Compton
Publikováno v: Mechanisms of Development. 126(7):517-522
Inactivating mutations in the tumor suppressor gene MEN1 cause the inherited cancer syndrome multiple endocrine neoplasia type 1 (MEN1). The ubiquitously expressed MEN1 encoded protein, menin, interacts with MLL (mixed-lineage leukemia protein), and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f3726e2a36cdbecf1f26e8eb49174f
Zobrazit plný text záznamu
4
Mouse Embryo Fibroblasts Lacking the Tumor Suppressor Menin Show Altered Expression of Extracellular Matrix Protein Genes
Autor: Nijaguna B. Prasad, Abdel G. Elkahloun, Rui Zhu Zhang, Francis S. Collins, Settara C. Chandrasekharappa, Sukhbir Kaur, Elizabeth A. Novotny, Youngmi Ji, Yi Chen, Sunita K. Agarwal, Stephen J. Marx, Mon-Li Chu
Publikováno v: Molecular Cancer Research. 5:1041-1051
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant familial cancer syndrome characterized primarily by endocrine tumors of the parathyroids, anterior pituitary, and enteropancreatic endocrine tissues. Affected individuals carry a ger
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0d3d69ef9deecd358daf09103f474e
https://doi.org/10.1158/1541-7786.mcr-06-0379
Zobrazit plný text záznamu
5
Menin molecular interactions: insights into normal functions and tumorigenesis
Autor: Frank H. Collins, Youngmi Ji, Peter C. Scacheri, Carmen M. Mateo, Allen M. Spiegel, Steven K. Libutti, Settara C. Chandrasekharappa, S. Rao, Brian Oliver, Alison B. Hickman, A L Burns, Aniello Cerrato, Elizabeth A. Novotny, Patricia A. Kennedy, Terri S. Rice, Sunita K. Agarwal, J.B. Moore, Stephen J. Marx
Publikováno v: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 37(6)
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disease predisposed by heterozygous germline mutations in the MEN1 tumor suppressor gene. Biallelic loss of MEN1 resulting from small mutation and/or loss of heterozygosity occurs in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d09348a1d02807a79dc4c05f0a969c8
https://pubmed.ncbi.nlm.nih.gov/16001329
Zobrazit plný text záznamu
7
The 32-kilodalton subunit of replication protein A interacts with menin, the product of the MEN1 tumor suppressor gene
Autor: Maxim V. Sukhodolets, Settara C. Chandrasekharappa, Francis S. Collins, Alison B. Hickman, Elizabeth A. Novotny, Sunita K. Agarwal, Stephen J. Marx, Allen M. Spiegel, Victor H. Obungu, A. Lee Burns, Judy S. Crabtree, Karen E. Sukhodolets
Publikováno v: Molecular and cellular biology. 23(2)
Menin is a 70-kDa protein encoded by MEN1, the tumor suppressor gene disrupted in multiple endocrine neoplasia type 1. In a yeast two-hybrid system based on reconstitution of Ras signaling, menin was found to interact with the 32-kDa subunit (RPA2) o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bdfcccf2c7f21aa4d2a5ca714e4558d
https://pubmed.ncbi.nlm.nih.gov/12509449
Zobrazit plný text záznamu
8
Design of modified oligodeoxyribonucleotide probes to detect telomere repeat sequences in FISH assays
Autor: Joseph G. Hacia, Stephen A. Woski, Melissa A. Ashlock, Francis S. Collins, Elizabeth A. Novotny, R. Aeryn Mayer
Publikováno v: Nucleic acids research. 27(20)
A series of dye-labeled oligonucleotide probes containing base and sugar modifications were tested for the ability to detect telomeric repeat sequences in FISH assays. These modified oligonucleotides, all 18 nt in length, were complementary to either
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f3e4d42fde68bffb7c9267018d6ff5f
https://pubmed.ncbi.nlm.nih.gov/10497268
Zobrazit plný text záznamu
9
Human artificial chromosomes generated by modification of a yeast artificial chromosome containing both human alpha satellite and single-copy DNA sequences
Autor: Xin Yuan Guan, Pengfei Liu, Melissa A. Ashlock, Elizabeth A. Novotny, Sheila T. Compton, Karla A. Henning
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 96(2)
A human artificial chromosome (HAC) vector was constructed from a 1-Mb yeast artificial chromosome (YAC) that was selected based on its size from among several YACs identified by screening a randomly chosen subset of the Centre d’Étude du Polymorp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47a85c063243d9f30e111f452b8715b
https://pubmed.ncbi.nlm.nih.gov/9892678
Zobrazit plný text záznamu
10
Functional human CFTR produced by stable Chinese hamster ovary cell lines derived using yeast artificial chromosomes
Autor: William B. Guggino, Yuan Jiang, Michael L. Bittner, Karla A. Henning, Elizabeth A. Novotny, Melissa A. Rosenfeld, Peter J. Mogayzel, Erik M. Schwiebert
Publikováno v: Human molecular genetics. 6(1)
The cystic fibrosis transmembrane conductance regulator gene (CFTR) encodes a transmembrane protein (CFTR) which functions in part as a cyclic adenosine monophosphate (cAMP)-regulated chloride channel. CFTR expression is controlled temporally and cel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0886470077477a8a5f565b327212156d
https://pubmed.ncbi.nlm.nih.gov/9002671
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje